↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Tyck till om SwePub Sök här!

Träfflista för sökning "WFRF:(Dahlman I) ;pers:(Thorell A)"

Sökning: WFRF:(Dahlman I) > Thorell A

Resultat 1-9 av 9

Sortera/gruppera träfflistan

Sortering: Träffar per sida:

Numrering	Referens	Omslagsbild	Hitta
1.	Arner, P, et al. (författare) The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women 2015 Ingår i: Clinical epigenetics. - : Springer Science and Business Media LLC. - 1868-7075 .- 1868-7083. ; 7, s. 93- Tidskriftsartikel (refereegranskat)
2.	Dahlman, I, et al. (författare) The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes. 2015 Ingår i: International Journal of Obesity. - : Springer Science and Business Media LLC. - 1476-5497 .- 0307-0565. ; 39:6, s. 910-919 Tidskriftsartikel (refereegranskat)abstract Obese subjects have increased number of enlarged fat cells which are reduced in size but not number in post-obesity. We performed DNA methylation profiling in fat cells with the aim of identifying differentially methylated DNA sites (DMS) linked to adipose hyperplasia (many small fat cells) in post-obesity.
3.	Arner, P, et al. (författare) Erratum to: The epigenetic signature of systemic insulin resistance in obese women 2016 Ingår i: Diabetologia. - : Springer Science and Business Media LLC. - 1432-0428 .- 0012-186X. ; 59:12, s. 2728-2728 Tidskriftsartikel (refereegranskat)
4.	Arner, P, et al. (författare) The epigenetic signature of systemic insulin resistance in obese women 2016 Ingår i: Diabetologia. - : Springer Science and Business Media LLC. - 1432-0428 .- 0012-186X. ; 59:11, s. 2393-2405 Tidskriftsartikel (refereegranskat)
5.	Andersson, DP, et al. (författare) Improved metabolism and body composition beyond normal levels following gastric bypass surgery: a longitudinal study 2019 Ingår i: Journal of internal medicine. - : Wiley. - 1365-2796 .- 0954-6820. ; 285:1, s. 92-101 Tidskriftsartikel (refereegranskat)
6.	Arner, P, et al. (författare) Screening of potential adipokines identifies S100A4 as a marker of pernicious adipose tissue and insulin resistance 2018 Ingår i: International journal of obesity (2005). - : Springer Science and Business Media LLC. - 1476-5497 .- 0307-0565. ; 42:12, s. 2047-2056 Tidskriftsartikel (refereegranskat)
7.	Jiao, H, et al. (författare) Exome sequencing followed by genotyping suggests SYPL2 as a susceptibility gene for morbid obesity 2015 Ingår i: European journal of human genetics : EJHG. - : Springer Science and Business Media LLC. - 1476-5438 .- 1018-4813. ; 23:9, s. 1216-1222 Tidskriftsartikel (refereegranskat)
8.	Jiao, H, et al. (författare) Whole-Exome Sequencing Suggests LAMB3 as a Susceptibility Gene for Morbid Obesity 2016 Ingår i: Diabetes. - : American Diabetes Association. - 1939-327X .- 0012-1797. ; 65:10, s. 2980-2989 Tidskriftsartikel (refereegranskat)abstract Identification of rare sequencing variants with a larger functional impact has the potential to highlight new pathways contributing to obesity. Using whole-exome sequencing followed by genotyping, we have identified a low-frequency coding variant rs2076349 (V527M) in the laminin subunit β3 (LAMB3) gene showing strong association with morbid obesity and thereby risk of type 2 diabetes. We exome-sequenced 200 morbidly obese subjects and 100 control subjects with pooled DNA samples. After several filtering steps, we retained 439 obesity-enriched low-frequency coding variants. Associations between genetic variants and obesity were validated sequentially in two case-control cohorts. In the final analysis of 1,911 morbidly obese and 1,274 control subjects, rs2076349 showed strong association with obesity (P = 9.67 × 10−5; odds ratio 1.84). This variant was also associated with BMI and fasting serum leptin. Moreover, LAMB3 expression in adipose tissue was positively correlated with BMI and adipose morphology (few but large fat cells). LAMB3 knockdown by small interfering RNA in human adipocytes cultured in vitro inhibited adipogenesis. In conclusion, we identified a previously not reported low-frequency coding variant that was associated with morbid obesity in the LAMB3 gene. This gene may be involved in the development of excess body fat.
9.	Ryden, M, et al. (författare) The Adipose Transcriptional Response to Insulin Is Determined by Obesity, Not Insulin Sensitivity 2016 Ingår i: Cell reports. - : Elsevier BV. - 2211-1247. ; 16:9, s. 2317-2326 Tidskriftsartikel (refereegranskat)

Skapa referenser, mejla, bekava och länka

Länka till träfflistan

Resultat 1-9 av 9

Avgränsa träffmängd

Typ av publikation: tidskriftsartikel (9)

Typ av innehåll: refereegranskat (9)

Författare/redaktör: Arner, P (9); Thorell, A (9)Ta bort avgränsningen; Dahlman, I (9); Ryden, M (7); Naslund, E (7); Sinha, I (4); visa fler...; Gao, H. (3); Kere, J (2); Johnson, T. (2); Andersson, DP (2); Xu, H (2); Toft, E (2); Gerdhem, P (2); Dahlman-Wright, K (2); Sahlqvist, AS (2); Yao, X (2); Waterworth, D (2); Rajpal, D (2); Loomis, AK (2); Freudenberg, JM (2); Jiao, H (2); Brodin, D (1); Backdahl, J (1); Perfilyev, Alexander (1); Ling, Charlotte (1); Hamsten, A (1); Daub, CO (1); Strawbridge, RJ (1); Esteve, D. (1); Hogling, DE (1); Qvisth, V (1); Bornholdt, J (1); Boyd, M (1); Sandelin, A (1); Henriksson, J (1); Andersson, D. P. (1); Kulyte, A (1); Petrus, P (1); Boulomie, A (1); Mileti, E. (1); Raman, A (1); Hrydziuszko, O (1); Qvist, V. (1); visa färre...

Lärosäte: Karolinska Institutet (9); Lunds universitet (1)

Språk: Engelska (9)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - Nationella bibliotekssystem
LIBRIS.kb.se

pil uppåt

Stäng

Kopiera och spara länken för att återkomma till aktuell vy