SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Extended search

Träfflista för sökning "WFRF:(Davidsson Åke) "

Search: WFRF:(Davidsson Åke)

  • Result 1-10 of 47
Sort/group result
   
EnumerationReferenceCoverFind
1.
  •  
2.
  • Davidsson, Josef, et al. (author)
  • Tiling resolution array comparative genomic hybridization, expression and methylation analyses of dup(1q) in Burkitt lymphomas and pediatric high hyperdiploid acute lymphoblastic leukemias reveal clustered near-centromeric breakpoints and overexpression of genes in 1q22-32.3
  • 2007
  • In: Human Molecular Genetics. - : Oxford University Press (OUP). - 0964-6906 .- 1460-2083. ; 16:18, s. 2215-2225
  • Journal article (peer-reviewed)abstract
    • Although gain of 1q occurs in 25% of Burkitt lymphomas (BLs) and 10% of pediatric high hyperdiploid acute lymphoblastic leukemias (ALLs), little is known about the origin, molecular genetic characteristics and functional outcome of dup(1q) in these disorders. Ten dup(1q)-positive BLs/ALLs were investigated by tiling resolution (32k) array CGH analysis, which revealed that the proximal breakpoints in all cases were near-centromeric, in eight of them clustering within a 1.4 Mb segment in 1q12-21.1. The 1q distal breakpoints were heterogeneous, being more distal in the ALLs than in the BLs. The minimally gained segments in the ALLs and BLs were 57.4 Mb [dup(1)(q22q32.3)] and 35 Mb [dup(1)(q12q25.2)], respectively. Satellite 11 DNA on 1q was not hypomethylated, as ascertained by Southern blot analyses of 15 BLs/ALLs with and without gain of 1q, indicating that aberrant methylation was not involved in the origin of dup(1q), as previously suggested for other neoplasms with 1q rearrangements. Global gene expression analyses revealed that five genes in the minimally 57.4 Mb gained region-B4GALT3, DAP3, RGS16, TMEM183A and UCK2-were significantly overexpressed in dup(1q)-positive ALLs compared with high hyperdiploid ALLs without dup(1q). The DAP3 and UCK2 genes were among the most overexpressed genes in the BL case with gain of 1q investigated. The DAP3 protein has been reported to be highly expressed in invasive glioblastoma multiforme cells, whereas expression of the UCK2 protein has been correlated with sensitivity to anticancer drugs. However, involvement of these genes in dup(1q)-positive ALLs and BLs has previously not been reported.
  •  
3.
  •  
4.
  • Davidsson, Åke, 1956-, et al. (author)
  • Allergen-induced changes of B-cell phenotypes in patients with allergic rhinitis
  • 1994
  • In: Rhinology. - Amsterdam, Netherlands : International Rhinologic Society. - 0300-0729 .- 1996-8604. ; 32:4, s. 184-190
  • Journal article (peer-reviewed)abstract
    • We investigated sub-populations of B-lymphocytes in nasal mucosa and peripheral blood of 17 patients with seasonal allergic rhinitis (birch pollen) and 10 controls. The study included provocation with allergen during the non-pollen season, during which no participant used medication. Samples were also taken during the pollen season. Subsets of B-cells as expressed by different CD antigens were investigated by immunohistochemistry on frozen sections and by flow cytometry of peripheral blood. Nasal CD23+ B-cells decreased in allergic patients during provocation, indicating that mature virgin CD23+ B-cells switch into a memory B-cell phenotype with loss of CD23 expression. This indicates differentiation towards cells that can represent a local source for IgE synthesis. No decrease was observed during the pollen season when the patients used medication. Serum IgE was significantly higher in allergic patients on all occasions. The observed up-regulation of CD40 expression on peripheral blood B-cells in allergic patients during the pollen season clearly indicate B-cell activation. Furthermore, a relative increase of CD19+ B-cells was observed in peripheral blood during provocation. Upregulation (by IL-4) of CD40 on B-cells which then may be stimulated by gp39 (CD40 ligand) can constitute an early and important event in the IgE-mediated allergic reaction.
  •  
5.
  • Davidsson, Åke, 1956- (author)
  • Allergidagen med temat : "Födoämnesöverkänslighet"
  • 2014
  • In: Lung och alllergiforum. - Stockholm : Svensk Lungmedicinsk Förening och Svenska Föreningen för Allergologi. - 2000-5237. ; :4, s. 29-33
  • Journal article (pop. science, debate, etc.)
  •  
6.
  •  
7.
  •  
8.
  •  
9.
  •  
10.
  •  
Skapa referenser, mejla, bekava och länka
  • Result 1-10 of 47
Type of publication
book (18)
journal article (18)
conference paper (5)
doctoral thesis (2)
editorial collection (1)
reports (1)
show more...
research review (1)
book chapter (1)
show less...
Type of content
peer-reviewed (22)
pop. science, debate, etc. (13)
other academic/artistic (12)
Author/Editor
Karlsson, Mats G, 19 ... (7)
Andersson, Sören, 19 ... (3)
Holmström, Mats (3)
Asghar, Naveed, 1983 ... (3)
Johansson, Magnus, 1 ... (3)
Gunaltay, Sezin (3)
show more...
Davidsson, Henrik (2)
Johansson, Bertil (2)
Borg, Åke (2)
Ekström, Tomas (2)
Davidsson, Josef (2)
Fredlund, Hans (2)
Fioretos, Thoas (1)
Lantz, Mikael (1)
Heldrup, Jesper (1)
Paulsson, Kajsa (1)
Andersson, Anna (1)
Melén, Erik (1)
Viale, G (1)
Wennergren, Göran, 1 ... (1)
Johansson, Björn (1)
Laurell, Thomas (1)
Jönsson, Hanna (1)
Stridh, Björn (1)
Romberg, Kerstin (1)
Schnürer, Anna (1)
Nordberg, Åke (1)
Sandberg, Ann-Sofie, ... (1)
Kotarsky, Knut (1)
Sárvári Horváth, Ilo ... (1)
Lindqvist, Richard (1)
Överby, Anna K. (1)
Nordén, Bengt, 1945 (1)
Bengtsson, Martin (1)
Sunnergren, Ola, 197 ... (1)
Emnéus, Jenny (1)
Olde, Björn (1)
Pedersen, Lars (1)
Eriksson, Ola (1)
Persson, Tobias (1)
Behrendtz, Mikael (1)
Schiöler, Linus, 197 ... (1)
Boketoft, Åke (1)
Hellström, Daniel (1)
Blom, Angelika (1)
Olofsson, J (1)
Owman, Christer (1)
Mårtensson, Per (1)
Westman, Marit (1)
Kreuger, Emma (1)
show less...
University
Uppsala University (20)
Örebro University (14)
Lund University (6)
University of Gothenburg (4)
Linköping University (3)
Umeå University (2)
show more...
Chalmers University of Technology (2)
University of Gävle (1)
Jönköping University (1)
Karlstad University (1)
show less...
Language
English (23)
Swedish (21)
French (2)
German (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (20)
Humanities (11)
Natural sciences (3)
Engineering and Technology (3)
Social Sciences (1)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view