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Sökning: WFRF:(Decaens T)

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1.
  • Hudson, Thomas J., et al. (författare)
  • International network of cancer genome projects
  • 2010
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 464:7291, s. 993-998
  • Tidskriftsartikel (refereegranskat)abstract
    • The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.
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2.
  • Phillips, Helen R. P., et al. (författare)
  • Global distribution of earthworm diversity
  • 2019
  • Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 366:6464, s. 480-
  • Tidskriftsartikel (refereegranskat)abstract
    • Soil organisms, including earthworms, are a key component of terrestrial ecosystems. However, little is known about their diversity, their distribution, and the threats affecting them. We compiled a global dataset of sampled earthworm communities from 6928 sites in 57 countries as a basis for predicting patterns in earthworm diversity, abundance, and biomass. We found that local species richness and abundance typically peaked at higher latitudes, displaying patterns opposite to those observed in aboveground organisms. However, high species dissimilarity across tropical locations may cause diversity across the entirety of the tropics to be higher than elsewhere. Climate variables were found to be more important in shaping earthworm communities than soil properties or habitat cover. These findings suggest that climate change may have serious implications for earthworm communities and for the functions they provide.
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3.
  • Perret, J., et al. (författare)
  • Time to refine the geography of biodiversity hotspots by integrating molecular data: The Mediterranean Basin as a case study
  • 2023
  • Ingår i: Biological Conservation. - 0006-3207. ; 284
  • Tidskriftsartikel (refereegranskat)abstract
    • Three decades ago, worldwide biodiversity hotspots were founded on the distributions of continental plants and vertebrates. Here, we question the timeliness of refining the geography of hotspots by basing their definition on more taxa, thanks to the molecular data available for hyper-diverse organisms such as insects, fungi and marine biota.To do so, we assess the temporal dynamic of molecular data acquisition and the geography of knowledge about lineages currently included or not into hotspot definition. Using the Mediterranean Basin hotspot as a case study, we examine the taxonomic and geographical facets of 175,828 DNA sequences distributed over 21,552 species, and 13,001 indexed biodiversity publications. We reveal a deeply fractured repartition of biodiversity research efforts within the hotspot regarding both barcoding efforts and publication activity, the northern side of the Mediterranean concentrating 84.16 % of the publications and 75.99 % of the public DNA sequences. In addition, 57.55 % of the sequences belong to lineages which were excluded from hotspots definition, with highly congruent geographical patterns among marine and continental lineages.Based on this analysis, we suggest 1) using the uneven geography of knowledge to rebalance sampling efforts towards poorly known regions within the Mediterranean hotspot, 2) handling the molecular corpus of orphan lineages to feed forthcoming multi-taxa biodiversity assessment initiatives, in order to 3) refine the geography of
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