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Lung cancer susceptibility locus at 5p15.33
- McKay, James D. (author)
- Hung, Rayjean J. (author)
- Gaborieau, Valerie (author)
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- Boffetta, Paolo (author)
- Chabrier, Amelie (author)
- Byrnes, Graham (author)
- Zaridze, David (author)
- Mukeria, Anush (author)
- Szeszenia-Dabrowska, Neonilia (author)
- Lissowska, Jolanta (author)
- Rudnai, Peter (author)
- Fabianova, Eleonora (author)
- Mates, Dana (author)
- Bencko, Vladimir (author)
- Foretova, Lenka (author)
- Janout, Vladimir (author)
- McLaughlin, John (author)
- Shepherd, Frances (author)
- Montpetit, Alexandre (author)
- Narod, Steven (author)
- Krokan, Hans E. (author)
- Skorpen, Frank (author)
- Elvestad, Maiken Bratt (author)
- Vatten, Lars (author)
- Njolstad, Inger (author)
- Chen, Chu (author)
- Goodman, Gary (author)
- Barnett, Matt (author)
- Loomis, Melissa M. (author)
- Lubinski, Jan (author)
- Matyjasik, Joanna (author)
- Lener, Marcin (author)
- Oszutowska, Dorota (author)
- Field, John (author)
- Liloglou, Triantafillos (author)
- Xinarianos, George (author)
- Cassidy, Adrian (author)
- Zelenika, Diana (author)
- Boland, Anne (author)
- Delepine, Marc (author)
- Foglio, Mario (author)
- Lechner, Doris (author)
- Matsuda, Fumihiko (author)
- Blanche, Helene (author)
- Gut, Ivo (author)
- Heath, Simon (author)
- Lathrop, Mark (author)
- Brennan, Paul (author)
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- (creator_code:org_t)
- 2008-11-02
- 2008
- English.
- In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 40:12, s. 1404-1406
- Journal article (peer-reviewed)
Abstract
Subject headings
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- We carried out a genome-wide association study of lung cancer (3,259 cases and 4,159 controls), followed by replication in 2,899 cases and 5,573 controls. Two uncorrelated disease markers at 5p15.33, rs402710 and rs2736100 were detected by the genome-wide data (P - 2 x 10(-7) and P = 4 x 10(-6)) and replicated by the independent study series (P = 7 x 10(-5) and P = 0.016). The susceptibility region contains two genes, TERT and CLPTM1L, suggesting that one or both may have a role in lung cancer etiology.
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- MEDICIN
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- art (subject category)
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- McKay, James D.
- Hung, Rayjean J.
- Gaborieau, Valer ...
- Boffetta, Paolo
- Chabrier, Amelie
- Byrnes, Graham
- show more...
- Zaridze, David
- Mukeria, Anush
- Szeszenia-Dabrow ...
- Lissowska, Jolan ...
- Rudnai, Peter
- Fabianova, Eleon ...
- Mates, Dana
- Bencko, Vladimir
- Foretova, Lenka
- Janout, Vladimir
- McLaughlin, John
- Shepherd, France ...
- Montpetit, Alexa ...
- Narod, Steven
- Krokan, Hans E.
- Skorpen, Frank
- Elvestad, Maiken ...
- Vatten, Lars
- Njolstad, Inger
- Axelsson, Tomas
- Chen, Chu
- Goodman, Gary
- Barnett, Matt
- Loomis, Melissa ...
- Lubinski, Jan
- Matyjasik, Joann ...
- Lener, Marcin
- Oszutowska, Doro ...
- Field, John
- Liloglou, Triant ...
- Xinarianos, Geor ...
- Cassidy, Adrian
- Zelenika, Diana
- Boland, Anne
- Delepine, Marc
- Foglio, Mario
- Lechner, Doris
- Matsuda, Fumihik ...
- Blanche, Helene
- Gut, Ivo
- Heath, Simon
- Lathrop, Mark
- Brennan, Paul
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- Nature Genetics
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