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| 2. |
- DILLNER, J
(författare)
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SEROLOGY OF HUMAN PAPILLOMAVIRUS
- 1995
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Ingår i: CANCER JOURNAL - FRANCE. - 0765-7846. ; 8:5, s. 264-269
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Forskningsöversikt (övrigt vetenskapligt/konstnärligt)
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| 3. |
- Kocjan, Boštjan J, et al.
(författare)
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Molecular methods for identification and characterization of novel papillomaviruses.
- 2015
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Ingår i: Clinical Microbiology and Infection. - : Elsevier BV. - 1469-0691 .- 1198-743X. ; 21:9, s. 808-816
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Forskningsöversikt (refereegranskat)abstract
- Papillomaviruses (PV) are a remarkably heterogeneous family of small DNA viruses that infect a wide variety of vertebrate species and are etiologically linked with the development of various neoplastic changes of the skin and mucosal epithelia. Based on nucleotide similarity, PVs are hierarchically classified into genera, species and types. Novel human PV (HPV) types are given a unique number only after the whole genome has been cloned and deposited with the International HPV Reference Center. As of March 09, 2015, 200 different HPV types, belonging to 49 species, had been recognized by the International HPV Reference Center. In addition, 131 animal PV types identified from 66 different animal species exist. Recent advances in molecular techniques have resulted in an explosive increase in the identification of novel HPV types and novel subgenomic HPV sequences in the last few years. Among PV genera, the Gamma-PV genus has been growing most rapidly in recent years with 80 completely sequenced HPV types, followed by Alpha- and Beta-PV genera that have 65 and 51 recognized HPV types, respectively. We reviewed in detail the contemporary molecular methods most often used for identification and characterization of novel PV types, including polymerase chain reaction, rolling circle amplification and next generation sequencing. Furthermore, we present a short overview of 12 and 10 novel HPV types recently identified in Sweden and Slovenia, respectively. Finally, an update on the International Human Papillomavirus Reference Center is provided.
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| 4. |
- Nicol, Alcina F., et al.
(författare)
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A summary of the 25th International Papillomavirus Conference 2009: Vaccines, screening, epidemiology and therapeutics
- 2010
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Ingår i: Journal of Clinical Virology. - : Elsevier BV. - 1386-6532. ; 47:3, s. 208-215
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Forskningsöversikt (refereegranskat)abstract
- The 25th International Papillomavirus Conference was held in Malmo, Sweden, on May 8-14, 2009. The conference encompassed all areas of papillomavirus (PV) research, from clinical vaccinology to molecular biology. This review highlights some of the 237 presentations and 887 abstracts which were presented and summarizes sessions on prophylactic vaccines, screening, epidemiology and therapeutics. Important advances included identification of variants in four genes associated with HPV persistence, new HPV detection are likely new infections and not latency reactivation, and development of effective DNA vaccines that targets E6/E7 genes of HPV11. Also, many studies from different countries demonstrated that HPV vaccination provided sustained protection and substantial reduction of disease burden in both women and men, and in HIV-infected neonates. All the references cited are from the abstract book of the IPV Conference. See http://www.hpv2009.org/. (C) 2009 Elsevier B.V. All rights reserved.
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