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Sökning: WFRF:(Ding B) > Stockholms universitet

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2.
  • Barber, R. M., et al. (författare)
  • Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015 : A novel analysis from the global burden of disease study 2015
  • 2017
  • Ingår i: The Lancet. - : Lancet Publishing Group. - 0140-6736 .- 1474-547X. ; 390:10091, s. 231-266
  • Tidskriftsartikel (refereegranskat)abstract
    • Background National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the highly standardised cause of death and risk factor estimates generated through the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) to improve and expand the quantification of personal health-care access and quality for 195 countries and territories from 1990 to 2015. Methods We mapped the most widely used list of causes amenable to personal health care developed by Nolte and McKee to 32 GBD causes. We accounted for variations in cause of death certification and misclassifications through the extensive data standardisation processes and redistribution algorithms developed for GBD. To isolate the effects of personal health-care access and quality, we risk-standardised cause-specific mortality rates for each geography-year by removing the joint effects of local environmental and behavioural risks, and adding back the global levels of risk exposure as estimated for GBD 2015. We employed principal component analysis to create a single, interpretable summary measure-the Healthcare Quality and Access (HAQ) Index-on a scale of 0 to 100. The HAQ Index showed strong convergence validity as compared with other health-system indicators, including health expenditure per capita (r=0·88), an index of 11 universal health coverage interventions (r=0·83), and human resources for health per 1000 (r=0·77). We used free disposal hull analysis with bootstrapping to produce a frontier based on the relationship between the HAQ Index and the Socio-demographic Index (SDI), a measure of overall development consisting of income per capita, average years of education, and total fertility rates. This frontier allowed us to better quantify the maximum levels of personal health-care access and quality achieved across the development spectrum, and pinpoint geographies where gaps between observed and potential levels have narrowed or widened over time. Findings Between 1990 and 2015, nearly all countries and territories saw their HAQ Index values improve; nonetheless, the difference between the highest and lowest observed HAQ Index was larger in 2015 than in 1990, ranging from 28·6 to 94·6. Of 195 geographies, 167 had statistically significant increases in HAQ Index levels since 1990, with South Korea, Turkey, Peru, China, and the Maldives recording among the largest gains by 2015. Performance on the HAQ Index and individual causes showed distinct patterns by region and level of development, yet substantial heterogeneities emerged for several causes, including cancers in highest-SDI countries; chronic kidney disease, diabetes, diarrhoeal diseases, and lower respiratory infections among middle-SDI countries; and measles and tetanus among lowest-SDI countries. While the global HAQ Index average rose from 40·7 (95% uncertainty interval, 39·0-42·8) in 1990 to 53·7 (52·2-55·4) in 2015, far less progress occurred in narrowing the gap between observed HAQ Index values and maximum levels achieved; at the global level, the difference between the observed and frontier HAQ Index only decreased from 21·2 in 1990 to 20·1 in 2015. If every country and territory had achieved the highest observed HAQ Index by their corresponding level of SDI, the global average would have been 73·8 in 2015. Several countries, particularly in eastern and western sub-Saharan Africa, reached HAQ Index values similar to or beyond their development levels, whereas others, namely in southern sub-Saharan Africa, the Middle East, and south Asia, lagged behind what geographies of similar development attained between 1990 and 2015. Interpretation This novel extension of the GBD Study shows the untapped potential for personal health-care access and quality improvement across the development spectrum. Amid substantive advances in personal health care at the national level, heterogeneous patterns for individual causes in given countries or territories suggest that few places have consistently achieved optimal health-care access and quality across health-system functions and therapeutic areas. This is especially evident in middle-SDI countries, many of which have recently undergone or are currently experiencing epidemiological transitions. The HAQ Index, if paired with other measures of health-system characteristics such as intervention coverage, could provide a robust avenue for tracking progress on universal health coverage and identifying local priorities for strengthening personal health-care quality and access throughout the world. Copyright © The Author(s). Published by Elsevier Ltd.
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3.
  • Aaltonen, T., et al. (författare)
  • Combination of CDF and D0 measurements of the W boson helicity in top quark decays
  • 2012
  • Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 85:7, s. 071106-
  • Tidskriftsartikel (refereegranskat)abstract
    • We report the combination of recent measurements of the helicity of the W boson from top quark decay by the CDF and D0 collaborations, based on data samples corresponding to integrated luminosities of 2.7-5.4 fb(-1) of p (p) over bar collisions collected during Run II of the Fermilab Tevatron collider. Combining measurements that simultaneously determine the fractions of W bosons with longitudinal (f(0)) and right-handed (f(+)) helicities, we find f(0) = 0.722 +/- 0.081[+/- 0.062(stat) +/- 0.052(syst)] and f(+) = -0.033 +/- 0.046[+/- 0.034(stat) +/- 0.031(syst)]. Combining measurements where one of the helicity fractions is fixed to the value expected in the standard model, we find f(0) = 0.682 +/- 0.057[+/- 0.035(stat) +/- 0.046(syst)] for fixed f(+) and f(+) = -0.015 +/- 0.035[+/- 0.018(stat) +/- 0.030(syst)] for fixed f(0). The results are consistent with standard model expectations.
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6.
  • Abazov, V. M., et al. (författare)
  • Measurements of single top quark production cross sections and vertical bar V(tb)vertical bar in p(p)over-bar collisions at root s=1.96 TeV
  • 2011
  • Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 84:11, s. 112001-
  • Tidskriftsartikel (refereegranskat)abstract
    • We present measurements of production cross sections of single top quarks in p (p) over bar collisions at root s = 1.96 TeV in a data sample corresponding to an integrated luminosity of 5.4 fb(-1) collected by the D0 detector at the Fermilab Tevatron Collider. We select events with an isolated electron or muon, an imbalance in transverse energy, and two, three, or four jets, with one or two of them containing a bottom hadron. We obtain an inclusive cross section of sigma(p (p) over bar -> tb + X, tqb + X) = 3.43(-0.74)(+0.73) pb and use it to extract the CKM matrix element 0.79 < vertical bar V(tb)vertical bar <= 1 at the 95% C.L. We also measure sigma(p<(p)over bar> -> tb + X) = 0.68(-0.35)(+0.38) pb and sigma(p (p) over bar -> tqb + X) = 2.86(-0.63)(+0.69) pb when assuming, respectively, tqb and tb production rates as predicted by the standard model.
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7.
  • Abazov, V. M., et al. (författare)
  • Search for Sneutrino Production in e mu Final States in 5.3 fb(-1) of p(p)over-bar Collisions at root s = 1.96 TeV
  • 2010
  • Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 105:19, s. 191802-
  • Tidskriftsartikel (refereegranskat)abstract
    • We report the results of a search for R parity violating (RPV) interactions leading to the production of supersymmetric sneutrinos decaying into e mu final states using 5.3 fb(-1) of integrated luminosity collected by the D0 experiment at the Fermilab Tevatron Collider. Having observed no evidence for production of e mu resonances, we set direct bounds on the RPV couplings lambda'(311) and lambda(312) as a function of sneutrino mass.
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8.
  • Abazov, V. M., et al. (författare)
  • Bounds on an Anomalous Dijet Resonance in W plus jets Production in p(p)over-bar Collisions at root s=1.96 TeV
  • 2011
  • Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 107:1, s. 011804-
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a study of the dijet invariant mass spectrum in events with two jets produced in association with a W boson in data corresponding to an integrated luminosity of 4.3 fb(-1) collected with the D0 detector at root s = 1.96 TeV. We find no evidence for anomalous resonant dijet production and derive upper limits on the production cross section of an anomalous dijet resonance recently reported by the CDF Collaboration, investigating the range of dijet invariant mass from 110 to 170 GeV/c(2). The probability of the D0 data being consistent with the presence of a dijet resonance with 4 pb production cross section at 145 GeV/c(2) is 8 x 10(-6).
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9.
  • Abazov, V. M., et al. (författare)
  • Direct measurement of the mass difference between top and antitop quarks
  • 2011
  • Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 84:5, s. 052005-
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a direct measurement of the mass difference between top and antitop quarks (Delta m) in lepton + jets t (t) over bar final states using the "matrix element" method. The purity of the lepton + jets sample is enhanced for t (t) over bar events by identifying at least one of the jets as originating from a b quark. The analyzed data correspond to 3.6 fb(-1) of p (p) over bar collisions at root s = 1.96 TeV acquired by D0 in Run II of the Fermilab Tevatron Collider. The combination of the e + jets and mu + jets channels yields Delta m = 0.8 +/- 1.8(stat) +/- 0.5(syst) GeV, which is in agreement with the standard model expectation of no mass difference.
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10.
  • Abazov, V. M., et al. (författare)
  • Evidence for Spin Correlation in t(t)over-bar Production
  • 2012
  • Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 108:3, s. 032004-
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a measurement of the ratio of events with correlated t and (t) over bar spins to the total number of t (t) over bar events. This ratio f is evaluated using a matrix-element-based approach in 729 t (t) over bar candidate events with a single lepton l (electron or muon) and at least four jets. The analyzed p (p) over bar collisions data correspond to an integrated luminosity of 5: 3 fb(-1) and were collected with the D0 detector at the Fermilab Tevatron collider operating at a center-of-mass energy root s = 1.96 TeV. Combining this result with a recent measurement of f in dileptonic final states, we find f in agreement with the standard model. In addition, the combination provides evidence for the presence of spin correlation in t (t) over bar events with a significance of more than 3 standard deviations.
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