Association of TNFSF15 polymorphism with irritable bowel syndrome.

• Irritable bowel syndrome (IBS) is the most common gastrointestinal disorder, affecting more than 10% of the general population worldwide. Although a genetic component is suspected, unambiguous susceptibility genes have so far not been identified. This study tested the hypothesis that genes contributing to epithelial barrier integrity, control of mucosal immune responses and interactions with bacteria in the gut are associated with IBS.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)

Keyword

Adult

Alleles

Constipation

genetics

Crohn Disease

genetics

Female

Genetic Association Studies

Genetic Predisposition to Disease

genetics

Genotype

Humans

Irritable Bowel Syndrome

genetics

Male

Middle Aged

Polymorphism

Single Nucleotide

genetics

Tumor Necrosis Factor Ligand Superfamily Member 15

genetics

Publication and Content Type

ref (subject category)

art (subject category)