| 1. |
|
|
| 2. |
- Alrutz, Marie, et al.
(författare)
-
Projektledning
- 2013
-
Bok (populärvet., debatt m.m.)abstract
- Projektledning är ett yrke med egen certifiering. Det pågår en spännande utveckling inom området och det blir allt viktigare att hålla sig ajour med utvecklingen.Det övergripande målet med den här handboken är att vara en ständigt aktuell heltäckande bok om projektarbete. Innehållsmässigt täcker den både frågor som har med struktur och styrning att göra och frågor om ledning av människor och mänskliga processer i grupp. Kompetens inom projekt byggs av både kunskap och erfarenhet. Vi följer kontinuerligt aktuell forskning inom dessa områden och bjuder in intressanta forskare att medverka som författare. Vi skildrar verkliga projekt och låter erfarenheterna få plats, både de bästa erfarenheterna och de utmaningar som man tagit sig igenom.Handboken är levande och det innebär att artiklar tas bort för att ge plats för nya, i takt med att den uppdateras fortlöpande.
|
|
| 3. |
- Ambrosi, Aurelie, et al.
(författare)
-
Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern
- 2012
-
Ingår i: Annals of the Rheumatic Diseases. - London : BMJ Publishing Group. - 0003-4967 .- 1468-2060. ; 71:3, s. 334-340
-
Tidskriftsartikel (refereegranskat)abstract
- Objective Congenital heart block may develop in the fetuses of Ro/SSA-positive and La/SSB-positive mothers. Recurrence rates of only 10-20% despite persisting maternal antibodies indicate that additional factors are critical for the establishment of heart block. The authors investigated the influence of other maternal and fetal factors on heart block development in a Swedish population-based cohort. less thanbrgreater than less thanbrgreater thanMethods The influence of fetal gender, maternal age, parity and time of birth on heart block development was analysed in 145 families, including Ro/La-positive (n=190) and Ro/La-negative (n=165) pregnancies. less thanbrgreater than less thanbrgreater thanResults There was a recurrence rate of 12.1% in Ro/La-positive women, and no recurrence in Ro/La-negative women. Fetal gender and parity did not influence the development of heart block in either group. Maternal age in Ro/La-positive pregnancies with a child affected by heart block was, however, significantly higher than in pregnancies resulting in babies without heart block (pandlt;0.05). Seasonal timing of pregnancy influenced the outcome. Gestational susceptibility weeks 18-24 occurring during January-March correlated with a higher proportion of children with heart block and lower vitamin D levels during the same period in a representative sample of Swedish women and a corresponding higher proportion of children with heart block born in the summer (pandlt;0.02). Maternal age or seasonal timing of pregnancy did not affect the outcome in Ro/La-negative pregnancies. less thanbrgreater than less thanbrgreater thanConclusion This study identifies maternal age and seasonal timing of pregnancy as novel risk factors for heart block development in children of Ro/La-positive women. These observations may be useful for counselling when pregnancy is considered.
|
|
| 4. |
|
|
| 5. |
- Andersson, Joel Håkan, 1981, et al.
(författare)
-
Solidification of alloy 718, ati 718Plus® and waspaloy
- 2014
-
Ingår i: 8th International Symposium on Superalloy 718 and Derivatives 2014. - Hoboken, NJ, USA : John Wiley & Sons, Inc.. - 9781634396424 ; , s. 181-192
-
Konferensbidrag (refereegranskat)abstract
- Alloy 718, ATI 718Plus® and Waspaloy have been investigated in terms of what their respective solidification process reveals. Differential thermal analysis was used to approach the task together with secondary electron and back scattered electron detectors equipped with an energy dispersive X-ray spectroscopy detector. These experimental methods were used to construct pseudo binary phase diagrams that could aid in explaining solidification as well as liquation mechanisms in processes such as welding and casting. Furthermore, it was seen that Waspaloy has the smallest solidification range, followed by Alloy 718, and finally ATI 718Plus® possessing the largest solidification interval in comparison.
|
|
| 6. |
|
|
| 7. |
- Bjerklöv, Kristian, Docent, et al.
(författare)
-
Positive fibered lyapunov exponents for some quasi-periodically driven circle endomorphisms with critical points
- 2020
-
Ingår i: Astérisque. - : Societe Mathematique de France. - 0303-1179 .- 2492-5926. ; 415, s. 181-193
-
Tidskriftsartikel (refereegranskat)abstract
- In this paper we give examples of skew-product maps T : T-2 -> T-2 of the form T (x, y) = (x + omega, x + f(y)), where f : T -> T is an explicit C-1-endomorphism of degree two with a unique critical point and omega belongs to a set of positive measure, for which the fibered Lyapunov exponent is positive for a.e. (x, y) is an element of T-2. The critical point is of type f '(+/- e(-epsilon)) approximate to e(-beta s/(ln s)2) for all large s, where beta > 0 is a small numerical constant.
|
|
| 8. |
|
|
| 9. |
- Carlsson, Marcus, et al.
(författare)
-
The quantitative contribution of AV-plane motion to LV pumping in controls, athletes and patients with dilated cardiomyopathy measured by MR imaging
- 2006
-
Konferensbidrag (refereegranskat)abstract
- The quantitative contribution of AV-plane motion to LV pumping in controls, athletes and patients with dilated cardiomyopathy measured by MR imaging Carlsson M, Hard L, Eliasson M, Mosén H, Ugander M, Buhre T, Arheden H. INTRODUCTION: Previous studies using echocardiography in healthy subjects have reported conflicting data regarding the percentage of the stroke volume resulting from atrioventricular plane motion (AVPM). AIM: To quantify the percentage of SV explained by AVPM in controls, athletes and patients with decreased left ventricular function due to dilated cardiomyopathy (DCM) using cardiac magnetic resonance (CMR) imaging. METHODS: 12 healthy subjects (mean age 24 years, 5 women), 12 elite triathletes (mean age 35 years, 4 women) and 12 patients with DCM and ejection fraction below 30 % (mean age 54 years, 4 women) were examined by cine CMR. Maximum AVPM between end-diastole and end-systole was measured at two points in each of three long axis planes and expressed as the average of the six points. The SV was calculated from contiguous short axis images by established techniques. The mean epicardial area of the largest short axis slices in end-diastole was multiplied by the AVPM and divided by the SV to calculate the percentage of SV explained by longitudinal function (AVPM/SV). Data is presented as mean±SEM. RESULTS: SV for controls was 116±6 ml. SV was increased in athletes 140±4 ml (p=0.01) and decreased in patients 72±7 ml (p<0.001). AVPM for controls was 16±0 mm. AVPM was unchanged for athletes 17±1 mm (p=ns) and decreased for patients 7±1 mm (p<0.001). AVPM/SV for controls was 60±2 %. AVPM/SV was unchanged for athletes 57±2 % (p=ns) and for patients 67±4 % (p=ns). CONCLUSIONS: AV-plane motion is the primary contributor to LV pumping accounting for about 60 % of the stroke volume. Although AVPM is less than half in patients with DCM compared to controls and athletes, the contribution of AVPM to LV function is maintained which can be explained by the larger short-axis area in the dilated left ventricle.
|
|
| 10. |
- Carrasquilla, Germán D, et al.
(författare)
-
Postmenopausal hormone therapy and risk of stroke : A pooled analysis of data from population-based cohort studies.
- 2017
-
Ingår i: PLoS Medicine. - : Public Library of Science (PLoS). - 1549-1277 .- 1549-1676. ; 14:11
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Recent research indicates a favourable influence of postmenopausal hormone therapy (HT) if initiated early, but not late, on subclinical atherosclerosis. However, the clinical relevance of timing of HT initiation for hard end points such as stroke remains to be determined. Further, no previous research has considered the timing of initiation of HT in relation to haemorrhagic stroke risk. The importance of the route of administration, type, active ingredient, and duration of HT for stroke risk is also unclear. We aimed to assess the association between HT and risk of stroke, considering the timing of initiation, route of administration, type, active ingredient, and duration of HT.METHODS AND FINDINGS: Data on HT use reported by the participants in 5 population-based Swedish cohort studies, with baseline investigations performed during the period 1987-2002, were combined in this observational study. In total, 88,914 postmenopausal women who reported data on HT use and had no previous cardiovascular disease diagnosis were included. Incident events of stroke (ischaemic, haemorrhagic, or unspecified) and haemorrhagic stroke were identified from national population registers. Laplace regression was employed to assess crude and multivariable-adjusted associations between HT and stroke risk by estimating percentile differences (PDs) with 95% confidence intervals (CIs). The fifth and first PDs were calculated for stroke and haemorrhagic stroke, respectively. Crude models were adjusted for age at baseline only. The final adjusted models included age at baseline, level of education, smoking status, body mass index, level of physical activity, and age at menopause onset. Additional variables evaluated for potential confounding were type of menopause, parity, use of oral contraceptives, alcohol consumption, hypertension, dyslipidaemia, diabetes, family history of cardiovascular disease, and cohort. During a median follow-up of 14.3 years, 6,371 first-time stroke events were recorded; of these, 1,080 were haemorrhagic. Following multivariable adjustment, early initiation (<5 years since menopause onset) of HT was associated with a longer stroke-free period than never use (fifth PD, 1.00 years; 95% CI 0.42 to 1.57), but there was no significant extension to the time period free of haemorrhagic stroke (first PD, 1.52 years; 95% CI -0.32 to 3.37). When considering timing as a continuous variable, the stroke-free and the haemorrhagic stroke-free periods were maximal if HT was initiated approximately 0-5 years from the onset of menopause. If single conjugated equine oestrogen HT was used, late initiation of HT was associated with a shorter stroke-free (fifth PD, -4.41 years; 95% CI -7.14 to -1.68) and haemorrhagic stroke-free (first PD, -9.51 years; 95% CI -12.77 to -6.24) period than never use. Combined HT when initiated late was significantly associated with a shorter haemorrhagic stroke-free period (first PD, -1.97 years; 95% CI -3.81 to -0.13), but not with a shorter stroke-free period (fifth PD, -1.21 years; 95% CI -3.11 to 0.68) than never use. Given the observational nature of this study, the possibility of uncontrolled confounding cannot be excluded. Further, immortal time bias, also related to the observational design, cannot be ruled out.CONCLUSIONS: When initiated early in relation to menopause onset, HT was not associated with increased risk of incident stroke, regardless of the route of administration, type of HT, active ingredient, and duration. Generally, these findings held also for haemorrhagic stroke. Our results suggest that the initiation of HT 0-5 years after menopause onset, as compared to never use, is associated with a decreased risk of stroke and haemorrhagic stroke. Late initiation was associated with elevated risks of stroke and haemorrhagic stroke when conjugated equine oestrogen was used as single therapy. Late initiation of combined HT was associated with haemorrhagic stroke risk.
|
|
