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  • Akner, Gunnar, 1953-, et al. (författare)
  • Vi står gärna bakom en utfallsbaserad vård
  • 2017
  • Ingår i: Dagens Samhälle. - 1652-6511.
  • Tidskriftsartikel (populärvet., debatt m.m.)abstract
    • <p>Jörgen Nordenström försöker få det till att vår kritik av värdebaserad vård egentligen handlar om att vi vill ha mer resurser. Han har helt missuppfattat oss, skriver 26 specialistläkare i en replik.</p>
  • Engstrom, My, et al. (författare)
  • Perception of Control Over Eating After Bariatric Surgery for Super-Obesity—a 2-Year Follow-Up Study
  • 2015
  • Ingår i: Obesity Surgery. - 0960-8923. ; 25:6, s. 1086-93
  • Tidskriftsartikel (refereegranskat)abstract
    • Physiological and psychosocial factors might contribute to differences in weight loss, eating behaviour and health-related quality of life (HRQoL) after bariatric surgery. The aim of this study was to investigate how perceived control over eating changes after bariatric surgery and whether it affects outcome in super-obese patients. In a retrospective analysis of a prospective study (n = 60), 49 patients were divided into two groups based on eating control 2 years after surgery, as assessed by the Three-Factor Eating Questionnaire-R21 (TFEQ-R21): 29 with good eating control (GC) and 20 patients with poor eating control (group PC). Eating behaviour and generic and condition-specific HRQoL was assessed by questionnaires. There were significant differences in all TFEQ-R21 domains 2 years after surgery in favour of group GC; uncontrolled eating p < 0.001, emotional eating p < 0.001 and for cognitive restraint p = 0.04. The improvement in HRQoL 2 years after surgery was significantly less in group PC compared to group GC in 7 of 8 SF-36 domains (p < 0.05). Mean (SD) percentage of excess body mass index lost was similar between groups, 71.2 (17.8) in group GC versus 65.4 (17.4) in group PC 2 years after surgery (p = 0.27). However, group GC had a significant weight loss between first and second year after surgery (p < 0.001) compared to group PC (p = 0.15). In super-obese patients, perceived poor control over eating 2 years after bariatric surgery was associated with lower HRQoL and more emotional and cognitive restraint eating, than good control overeating.
  • Gedda, Hans, et al. (författare)
  • Energy redistribution during CO2 laser cladding
  • 2002
  • Ingår i: Journal of laser applications. - 1042-346X .- 1938-1387. ; 14:2, s. 78-82
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>This article examines the factors that effect the efficiency of the CO sub 2 -laser powder cladding process. By theoretical calculation and experimental work it has been possible to identify how much of the original laser energy contributes to the cladding process and how much is lost to the surrounding environment by reflection, radiation, convection, etc. Every aspect of energy redistribution has been analyzed and quantified and this has led to a deeper understanding of the process. The article concludes with a number of suggestions for improving the efficiency of blown powder laser cladding.</p>
  • Gedda, Hans, et al. (författare)
  • Energy redistribution during CO2 laser cladding
  • 2001
  • Ingår i: Congress proceedings : Laser Materials Processing Conference; Laser Microfabrication Conference [at] ICALEO 2001, 20th International Congress on Applications of Lasers & Electro-Optics : October 15 - 18, 2001, Adam's Mark Hotel, Jacksonville, Florida, USA. - Orlando, Fla : Laser institute of America. - 912035730 ; s. 549-558
  • Konferensbidrag (refereegranskat)abstract
    • <p>This paper examines the factors that effect the efficiency of the CO sub 2 -laser powder cladding process. By theoretical calculation and experimental work it has been possible to identify how much of the original laser energy contributes to the cladding process and how much is lost to the surrounding environment by reflection, radiation, convection etc. Every aspect of energy redistribution has been analysed and quantified and this has lead to a deeper understanding of the process. The paper concludes with a number of suggestions for improving the efficiency of blown powder laser cladding</p>
  • Nilsson, Anna G, et al. (författare)
  • Prospective evaluation of long-term safety of dual-release hydrocortisone replacement administered once daily in patients with adrenal insufficiency.
  • 2014
  • Ingår i: European journal of endocrinology / European Federation of Endocrine Societies. - 1479-683X. ; 171:3, s. 369-77
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: The objective was to assess the long-term safety profile of dual-release hydrocortisone (DR-HC) in patients with adrenal insufficiency. Design: Randomized, open-label, crossover trial of DR-HC or thrice-daily hydrocortisone for 3 months each (stage 1) followed by two consecutive, prospective, open-label studies of DR-HC for 6 months (stage 2) and 18 months (stage 3) at five university clinics in Sweden. Methods: Sixty-four adults with primary AI started stage 1 and an additional 16 entered stage 3. Patients received DR-HC 20-40 mg once daily and hydrocortisone 20-40 mg divided into three daily doses (stage 1 only). Main outcome measures were adverse events (AEs) and intercurrent illness (self-reported hydrocortisone use during illness). Results: In stage 1, patients had a median 1.5 (range 1-9) intercurrent illness events with DR-HC and 1.0 (1-8) with thrice-daily hydrocortisone. AEs during stage 1 were not related to the cortisol exposure-time profile. The percentage of patients with one or more AEs during stage 1 (73.4% with DR-HC; 65.6% with thrice-daily hydrocortisone) decreased during stage 2, when all patients received DR-HC (51% in the first 3 months; 54% in the second 3 months). In stages 1-3 combined, 19 patients experienced 27 serious AEs, equating to 18.6 serious AEs/100 patient-years of DR-HC exposure. Conclusions: This long-term prospective trial is the first to document the safety of DR-HC in patients with primary AI, and has demonstrated that such treatment is well tolerated during 24 consecutive months of therapy.
  • Steiner, Håkan, et al. (författare)
  • Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature 292 : 246-248. 1981.
  • 2009
  • Ingår i: Journal of immunology (Baltimore, Md. : 1950). - 1550-6606. ; 182:11, s. 6635-7
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>Immune responses have been described for many different insect species. However, it is generally acknowledged that immune systems must therefore differ from those of vertebrates. An effective humoral immune response has been found in pupae of the cecropia moth, Hyalophora cecropia. The expression of this multicomponent system requires de novo synthesis of RNA and proteins and its broad antibacterial activity is due to at least three independent mechanisms, the most well known of which is the insect lysozyme. However, this enzyme is bactericidal for only a limited number of Gram-positive bacteria. WE recently purified and characterized P9A and P9B, which are two small, basic proteins with potent antibacterial activity against Escherichia coli and several other Gram-negative bacteria. We believe that P9A and P9B plays an important part in the humoral immune responses described previously and that the P9 proteins represent a new class of antibacterial agents for which we propose the name cecropins. We describe here the primary structures of cecropins A and B. We also show that cecropin A is specific for bacteria in contrast to melittin, the main lytic component in bee venom which lyses both bacteria and eukaryotic cells.</p>
  • 14th NOLAMP Conference The 14th Nordic Laser Materials Processing Conference, August 26th – 28th 2013, Gothenburg, Sweden
  • 2013
  • Samlingsverk (redaktörskap) (övrigt vetenskapligt)abstract
    • <p>Laser is a key element in obtaining a sustainable economy in Europe. Innovative laser processes will play a significant role in future green manufacturing as they provide a precise, well-controlled and highly effective energy deposition to the workpiece. Future challenges are to increase the spectrum of laser manufacturing technologies in all sectors where the laser can offer innovative product solutions, higher product quality, less environmental impact, higher productivity and in turn cost benefits.The NOLAMP conferences address all aspects of laser materials processing from fundamental science to industrial applications. The first NOLAMP conference took place in Oslo in 1987 in a period of intense development of the laser processes and their industrial applications. The NOLAMP has continued on a biannual cycle ever since, strengthening the Nordic laser community by encouraging knowledge transfer and networking. Now, 26 years later, in the forthcoming 14th NOLAMP, the research and development of processes like laser welding, laser hybrid welding, laser cutting and laser surface treatment is still very important, as well as the development of industrial applications and equipment for laser material processing. This time the NOLAMP Conference will be held in Gothenburg, Sweden. In this highly industrialized region of Sweden and with the close distance to Denmark, Norway and Finland, we hope to attract a strong participation from industry and the scientific community. On behalf of the Nordic laser community and Luleå University of Technology, it is our great pleasure to invite you to the 14th NOLAMP conference.</p>
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