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Träfflista för sökning "WFRF:(Engström Hans) ;pers:(Engström Sven)"

Search: WFRF:(Engström Hans) > Engström Sven

  • Result 1-9 of 9
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1.
  • Akner, Gunnar, 1953-, et al. (author)
  • Vi står gärna bakom en utfallsbaserad vård
  • 2017
  • In: Dagens Samhälle. - 1652-6511.
  • Journal article (pop. science, debate, etc.)abstract
    • Jörgen Nordenström försöker få det till att vår kritik av värdebaserad vård egentligen handlar om att vi vill ha mer resurser. Han har helt missuppfattat oss, skriver 26 specialistläkare i en replik.
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  • Merclin, Nadia, et al. (author)
  • Transdermal delivery from a lipid sponge phase—iontophoretic and passive transport in vitro of 5-aminolevulinic acid and its methyl ester
  • 2004
  • In: Journal of Controlled Release. - : Elsevier BV. - 0168-3659 .- 1873-4995. ; 100:2, s. 191-198
  • Journal article (peer-reviewed)abstract
    • The hydrochloride salts of 5-aminolevulinic acid (ALA) and its methyl ester (m-ALA), respectively, were dissolved in a lipid sponge phase comprising monoolein, propylene glycol and aqueous buffer at concentrations of approximately 0.25% and 16% w/w m-ALA. The iontophoretic and passive delivery of ALA and m-ALA from this formulation through porcine skin in vitro were measured and compared to formulations used in clinical practice, 20% w/w ALA in Unguentum M and Metvix(R) (a cream containing 16% w/w m-ALA). A sponge phase with 16% w/w m-ALA showed a higher passive flux (approximately 140 nmol cm(-2) h(-1) at 5 h) but a lower iontophoretic flux (approximately 800 nmol cm(-2) h(-1) at 5 h) compared to the clinically used products but the differences are hardly significant due to large standard deviations. ALA and m-ALA in sponge phase formulation showed iontophoretic fluxes in the range 80-100 nmol cm(-2) h(-1) at 3 h, i.e. values comparable to the passive fluxes from the more concentrated vehicles. The results demonstrate that the lipid sponge phase, a thermodynamically stable liquid with amphiphilic character, may have potential as a transdermal drug delivery vehicle.
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  • Ridell, Annika, et al. (author)
  • On the water content of the solvent/monoolein/water sponge (L3) phase
  • 2003
  • In: Colloids and Surfaces A. - 0927-7757 .- 1873-4359. ; 228:1-3, s. 17-24
  • Journal article (peer-reviewed)abstract
    • The water content of the solvent/monoolein/water sponge phase depends on the lipophilicity of the solvent used. The relatively lipophilic solvent 2-methyl-2,4-pentanediol (MPD) gives a sponge phase at about 60 wt.% water compared with 30 wt.% for the sponge phase formed with polyethylene glycol (Mw≈400, PEG 400). A reasonably good correlation is found between the water content of the sponge phase and the octanol/water partition coefficient for the solvent. The water content of the PEG 400 sponge phase increases considerably (to about 50 wt.%) by adding up to 3 wt.% of ionic compounds such as SDS, CTAB and salts of amphiphilic drugs. Nonionic detergents show less effect on increasing the water content, whereas membrane lipids such as lecithins and cholesterol show unchanged or even decreasing effect on the water content of the sponge phase.
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  • Result 1-9 of 9
Type of publication
journal article (8)
other publication (1)
Type of content
peer-reviewed (5)
pop. science, debate, etc. (3)
other academic/artistic (1)
Author/Editor
Engström, Sven (8)Undo refine
Järhult, Bengt (4)
Ekerstad, Niklas (4)
Tjärnström, Johan (4)
Wingstrand, Hans (4)
Ervander, Cecilia (4)
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Hagström, Bertil (4)
Hallén, Ola (4)
Järhult, Johannes (4)
Löfmark, Rurik (4)
Schmitt, Christian (4)
Styrud, Johan (4)
Svenberg, Torgny (4)
Andersson, Christer (3)
Akner, Gunnar, 1953- (3)
Petersson, Christer (3)
Elisasson, Mats (3)
Flordal, Per Anders (3)
Halldin, Jan (3)
Lind, Helena (3)
Rutegård, Jörgen (3)
Sandberg, CG (3)
Sjögren, Jonas (3)
Westergren, Hans (3)
Cizinsky, Stella (3)
Sparr, Emma (2)
von Zur-Mühlen, Beng ... (2)
Merclin, Nadia (2)
Nyden, Magnus (1)
Nilsson, Anders (1)
Bruchfeld, Annette (1)
Holm, Herman (1)
Jacobsson, Lars (1)
Littorin, Nils (1)
Eliasson, Mats (1)
Gustafson, Yngve (1)
Petetrsson, Christer (1)
Zur-Mühlen B, Bengt (1)
Högström, Magnus (1)
Berggren, Lars (1)
Serrander, Martin (1)
Rosenqvist, Mårten (1)
Bergstad, Bo (1)
Bertholds, Eric (1)
Bitkover, Catarina (1)
Björgell, Per (1)
Bruchfeld, Judith (1)
Carlsson, Jörg (1)
Dellmark, Yvonne (1)
Fridén, Jan (1)
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University
Uppsala University (5)
Linnaeus University (3)
Lund University (2)
Chalmers University of Technology (1)
Karolinska Institutet (1)
Language
Swedish (4)
Undefined language (3)
English (2)
Research subject (UKÄ/SCB)
Medical and Health Sciences (5)
Natural sciences (1)

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