Sökning: WFRF:(Erfurth Eva Marie)
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Obesity and metabol...
Obesity and metabolic disturbances in adamantinomatous craniopharyngioma patients
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- Erfurth, Eva Marie (författare)
- Lund University,Lunds universitet,Medicin/akutsjukvård, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Endokrin,Forskargrupper vid Lunds universitet,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Endocrine,Lund University Research Groups,Skåne University Hospital
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(creator_code:org_t)
- 2017-04-21
- 2017
- Engelska 15 s.
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Ingår i: Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma. - Cham : Springer International Publishing. - 9783319518909 - 9783319518886 ; , s. 85-99
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http://dx.doi.org/10...
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Abstract
Ämnesord
Stäng
- An adamantinous craniopharyngioma (CP) is rare benign pituitary tumour often growing invasively and thereby affecting the hypothalamus. The recurrence rate in CP is high and therapy of choice is surgery, followed by cranial radiotherapy (CRT) in about half of the patients. Patients with CP have a 3-19 fold higher cardiovascular mortality in comparison to the general population. The majority of patients have an extended hypopituitarism that needs balanced hormone supplementation. About half of the patient population suffer from hypothalamic damage due to the tumour or operation. These patients suffer from hypothalamic obesity together with increased vascular morbidity and compromised bone health, thirst disorders as well as somnolence and sleep apnea. Cardiovascular risk factors need up front therapy. There is a need for centralising this rare aggressive and difficult tumour to only a few centres and that it will be managed by a multidisciplinary team with experienced neurosurgeons, endocrinologists, neurooncologists, neuroradiologists, and neuroopthamologists for a better prognosis.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Bone mineral density
- Cardiovascular diseases
- Cardiovascular morbidity
- Cardiovascular mortality
- Cardiovascular risk factors
- Childhood craniopharyngioma
- Hypothalamic damage
- Insulin
- Leptin resistance
Publikations- och innehållstyp
- kap (ämneskategori)
- ref (ämneskategori)
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