Thromboembolism in orthopedic surgery: Scope of the problem

• Major surgery or traumas of the lower extremities trigger the coagulation cascade, and the physiologic equilibrium between factors promoting and retarding coagulation is disturbed resulting in a hypercoagulable state. In these patients, a reduced venous flow and impaired endothelial function further increase the risk of developing deep-vein thrombosis and pulmonary embolism. Pulmonary embolism is estimated to contribute to half of all perioperative mortality after major orthopedic surgery in unprotected patients, and deep-vein thrombosis is the main source of pulmonary emboli.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Nyckelord

Antithrombotic drugs

Orthopedic surgery

Thromboembolism

Publikations- och innehållstyp

ref (ämneskategori)

kap (ämneskategori)