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- Brorsson, Annelie, 1963, et al.
(författare)
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Development and evaluation of a new seated heel-rise test in the early stages of rehabilitation after an acute Achilles tendon rupture.
- 2014
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Ingår i: 16th ESSKA (European Society of Sports Traumatology, Knee Surgery and Arthroscopy) Congress, 14-17 May 2014, Amsterdam, Netherlands.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The early stages of rehabilitation appear to be of great importance for outcome after an Achilles tendon rupture. It is a challenge to evaluate the patients’ calf muscle endurance at this stage in a safe and adequate way. The aim of our study was to develop a seated heel-rise test suitable for evaluating calf muscle endurance three months after an Achilles tendon rupture. Furthermore we wanted to evaluate how the seated heel-rise test correlated to the ability to perform one-legged standing heel-rise and patient-reported symptoms. Method: Ninety-three patients, 79 men and 14 women, mean age of 40 (20-63) years, were included from a cohort of 100 patients participating in a prospective, randomized controlled trial comparing non-surgical and surgical treatment after Achilles tendon rupture. Forty-seven were treated with surgery and 46 with non-surgery. They were evaluated after 3, 6 and 12 months. Patient reported outcome was evaluated with Achilles Tendon Rupture Score (ATRS) and functional outcome with seated and standing heel-rise test. The seated heel-rise test was performed with the patient sitting with hip and knee in 90°. A leg extension weight-training machine was used to provide load onto the patient’s thigh at 50% body weight. The limb symmetry index (LSI=injured/healthy x 100) was calculated in order to compare the results from the seated and standing heel-rise test. Results: Ninety-one patients out of 93 (98%) could perform the seated heel-rise test. At the 3-month follow-up there was a significant difference (p<0.01) in the seated heel-rise test between the injured and the healthy side. There were no significant differences between the surgical and non-surgical treatment groups. There were significant differences in the seated heel-rise test and in ATRS (p<0.01) when comparing the group who could perform a standing heel-rise test at the 3-months follow-up, with the group who could not. There were significant correlations between the LSI-values in the seated heel-rise height at the 3-month follow-up and the standing heel-rise height at the 6-month (r=0.36, p<0.001, n= 91) and the 12-month follow-up (r=0.35, p=0.001, n=85). There were also significant correlations (r=0.22-0.37, p=<0.04) between the seated heel-rise test and ATRS. Conclusions: The seated heel-rise-test has the capacity to identify differences between the injured and the healthy side three months after injury. This test also correlates with patient reported outcomes and the heel-rise ability at 6 and 12 months. This test appears to be a safe and suitable test for evaluating calf muscle endurance and function in the early stages of rehabilitation after an Achilles tendon rupture.
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| 2. |
- Brorsson, Annelie, 1963, et al.
(författare)
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Long-term follow up after acute Achilles tendon rupture.
- 2015
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Ingår i: Danish Sports Medicine Congress, Copenhagen, January 22-24, 2015. - : Danish Association of Sports Medicine.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- It is still unknown why many patients never fully recover after an Achilles tendon rupture (ATR). The aim of this study was to perform a long-term follow-up (5-9 years) of patients treated either surgically or non-surgically after an ATR. Furthermore, we wanted to examine if the patients had a tendon elongation on the injured side and evaluate if this correlated to function, symptoms and foot structure. Material and Method Sixty-seven patients (13 women) mean age of 50 years were evaluated 5-9 years after injury. Thirty-five patients were treated with surgery and 32 with non-surgery. Patient reported outcome and activity level, lower leg function, tendon length, and foot-structure were evaluated. Both the healthy and the injured side were examined and the limb symmetry index (LSI=injured/healthy x 100) was calculated. Results There were significant differences between the healthy and injured side in all function tests (p<0.001-0.015) and the tendon was significantly longer on the injured side (p<0.001) independent of treatment. There were no significant correlations between tendon length and patient reported outcome, function or foot structure. The heel-rise height increased significantly (p<0.000) from the 1 year- to the 5-9-years-follow up. The mean Achilles tendon Total Rupture Score (ATRS) was 91/100, indicating minor symptoms. Conclusion: Patients with an Achilles tendon rupture continues to have significant deficits in tendon structure and function 5-9 years after injury. There is, however continued improvement between the 1 and 5-9 year follow-up.
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| 3. |
- Johansson, Barbro, et al.
(författare)
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Postischemic housing in an enriched environment influences hippocampal progenitor cell differentiation after focal cortical ischemia
- 2004
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Ingår i: Maturation Phenomenon in Cerebral Ischemia V. - 9783540408741 ; , s. 297-308
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Konferensbidrag (refereegranskat)abstract
- We have tested the hypothesis that environmental factors can influence postischemic progenitor cell survival and differentiation in the dentate gyrus. The proliferation marker bromodeoxyuridine (BrdU) was administered during 7 days starting 24 h after ligation of the right middle cerebral artery. Postoperatively the rats were housed in standard cages or transferred to enriched environment 24 h or 7 days after the ligation. Rats housed in standard cages performed significantly worse than rats housed in an enriched environment in a leg placement and a rotating pole test four weeks after the arterial ligation. Neurogenesis and gliogenesis were determined by triple labeling with antibodies against BrdU, the astrocytic marker glial fibrillary acidic protein (GFAP), and the neuronal markers Calbindin D28k and NeuN. Rats with cortical lesions had a 5- to 6-fold increase in BrdU labeled cells on the ipsilateral side (p<0.001 for the delayed enriched group; p<0.01 for the early enriched and standard groups) and a 2- to 3-fold non-significant increase on the contralateral side with no significant differences between the groups. About 80% of the BrdU-positive cells co-labeled with NeuN and about 70% of the BrdU-positive cells co-labeled with Calbindin D28K. Although housing conditions did not influence neurogenesis it markedly altered gliogenesis. Whereas the standard group did not have more astrocytes than sham-operated rats on the ipsilateral side, the early and delayed enriched group had a 3- to 5-fold increase, respectively, thereby normalizing the severely disturbed neuron to glia ratio in the standard group. We hypothesize that the newly formed neurons in the standard group would have a poor environment in the absence of a concomitant gliogenesis. Astrocytes play an important role in neuronal plasticity, and we propose that more attention should be given to gliogenesis in experimental studies on cell proliferation and differentiation after brain lesions.
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