| 1. |
- Andersen, Henrik Rasmus, et al.
(författare)
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Estrogenic personal care products in a greywater reuse system
- 2007
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Ingår i: Water Science and Technology. - : IWA Publishing. - 0273-1223 .- 1996-9732. ; 56:12, s. 45-49
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Tidskriftsartikel (refereegranskat)abstract
- The occurrence and fate of parabens in a greywater system was assessed. The potential for removal of residual paraben concentrations in effluent greywater with chlorine dioxide was also investigated. The influent to the greywater plant was characterised by considerable variation, with concentrations from below the detection limit to 40 μg/L and the five commonly used parabens in consumer products were frequently detected. After the biological treatment only two paraben were detected with concentration from 65–120 ng/L. Chlorine dioxide treatment of the biologically treated effluent with dosages down to 0.75 mg/L resulted in more than 97% reduction of all parabens. Formation of the by-product chloroform was insignificant from the chlorine dioxide treatment.
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| 2. |
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| 3. |
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| 4. |
- Andersson, Håkan S., 1967-, et al.
(författare)
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The toxicity of ribbon worms: alpha-nemertides or tetrodotoxin, or both?
- 2016
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Ingår i: Planta Medica. - : Georg Thieme Verlag KG. - 0032-0943 .- 1439-0221. ; 82:Supplement 1
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The marine ribbon worms (nemerteans) are predators which capture their prey by everting a proboscis carrying a mixture of toxins which brings on rapid paralysis [1]. Moreover, ribbon worms have a thick layer of epidermal mucus of similar constitution. Tetrodotoxin (TTX) has been identified as one of these toxins [2]. The extreme toxicity of TTX (lethal by ingestion of 0.5-2 mg) is due to its ability to block voltage-gated sodium channels. Although several bacterial species (among these Vibrio sp.) have been linked to its synthesis, the biogenic origin and biosynthesis is unclear. One hypothesis is that TTX production occurs in a symbiotic relationship with its host, in this case the ribbon worm [3]. We have made significant effort to identify TTX in a setup for production through the cultivation of Vibrio alginolyticus in nutrient broth infused with mucus from the ribbon worm Lineus longissimus. Toxicity was demonstrated by fraction injections into shore crabs, but no TTX was found, and it could be shown conclusively that toxicity was unrelated to TTX and the Vibrio culture itself, and rather a constituent of the ribbon worm mucus [4]. The following studies led us to the discovery of a new class of peptides, the alpha-nemertides, in the mucus of the ribbon worms, which could be directly linked to the toxic effects. A literature review of the available evidence for TTX in ribbon worms show that the evidence in most cases are indirect, although notable exceptions exist. This points to the necessity to further investigate the presence and roles of TTX and alpha-nemertides in ribbon worms.
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| 5. |
- Arvin, Erik, et al.
(författare)
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Water Education ved DTU : en e-læringplatform i Moodle til individualiseret kompetenceopbygning i samfundets vandsektor
- 2010
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Ingår i: Læring og Medier. - : Det Kgl. Bibliotek/Royal Danish Library. - 1903-248X. ; :6, s. 1-15
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Omstruktureringen af kommunerne i forbindelse med amternes nedlæggelse og privatiseringen af det danske samfunds vand- og spildevandsforsyning har givet store omvæltninger og nye udfordringer for mange personalegrupper. I vandbranchen er der derfor i dag et stort behov for individualiseret kompetenceopbygning inden for hele vandets kredsløb, afstrømmet regnvand, overfladevand, grundvand, vandforsyning, spildevandstransport og -rensning samt vandkvalitet og vandhygiejne.At behovet for efter- og videreuddannelse er stort beror på et skøn baseret på samtaler med fagpersoner i branchen. Desværre foreligger der ikke konkrete behovsopgørelser, og det er også uklart, hvor stor betalingsviljen til kompetenceudvikling er hos virksomhederne og kommunerne.Der er i dag det samme behov for et kompetenceløft på universitetsområdet, fordi der er sket en markant internationalisering, hvorved mange udenlandske studerende følger engelsksprogede masterprogrammer. På Danmarks Tekniske Universitet (DTU) foregår alle masterkurser på engelsk, og ca. halvdelen af de studerende på DTU Miljø's (Institut for Vand og Miljøteknologi) masterkurser er udenlandske gæstestuderende. Det er i dag en væsentlig opgave/problem at sikre, at disse studerende har de nødvendige faglige forudsætninger, når de starter på de planlagte kurser. Ellers sænkes undervisningsniveauet markant, og ressourceforbruget af hjælpelærere øges. Så også her er der brug for tilbud om individualiseret kompetenceopbygning.Men også over for de danske studerende er der behov for markante ændringer i undervisningsmetoderne. Der er en klar tendens til, at mange studerende bruger lærebøgerne som referenceværker. En voksende andel af de studerende sidder ikke mere og læser lærebøgerne igennem som i "gamle dage". E-læring kan være et middel til at give effektiv læring til disse mange studerende, der fra barnsben er tilvænnet IT-verdenen.I fremtiden vil der blive mere utraditionelle undervisningsbehov. Nogle større virksomheder vil i fremtiden skulle satse mere på salg af integrerede løsninger, f.eks. vand- og spildevandsløsninger for hele byområder. Dette kræver, at der er kompetente personer hos bygherrerne til at drive de fremtidige komplekse systemer. Her kan tilbud om uddannelse af bygherrens personale indgå som en konkurrenceparameter i virksomhedernes tilbud. Og netop her vil et fleksibelt e-læringssystem kunne få stor betydning.Målsætningen for udvikling af e-læringssystemet Water Education ved DTU er at opfylde ovennævnte undervisningsbehov. Projektet er i en udviklingsfase, hvorfor de praktiske erfaringer om udvikling af e-læringsmodulerne og brugernes vurderinger af fordele og ulemper er begrænsede. IT- og Telestyrelsen har medfinansieret projektet og deltaget aktivt i følgegruppemøder.
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| 6. |
- Eriksson, Eva, 1973-, et al.
(författare)
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Greywater pollution variability and loadings
- 2009
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Ingår i: Ecological Engineering. - : Elsevier BV. - 0925-8574 .- 1872-6992. ; 35:5, s. 661-669
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Tidskriftsartikel (refereegranskat)abstract
- Small on-site greywater treatment and reuse plants are susceptible to high short-term variation in flow and pollutant concentrations. As demonstrated in this study of a bathroom greywater plant in Copenhagen, Denmark, the flow ranges from no-flow periods to high-flow periods reaching 34 l min−1. Concentrations of both macro- and micro-pollutants (organic matter and parabens) were found to range by several orders of magnitude in the influent, based on sampling every 20 min. Paraben degradation was proven to occur in the rotating biological contactor (RBC), while the remnant organic matter in the effluent was proved not to be readily degradable. Ammonium content, presumably from urine contamination, was found to undergo nitrification in the RBC. Mass flow (daily loads) for individual substances was calculated for several pollutants. Macropollutants were found to be generated in low numbers of grams per person per day, whereas the paraben loadings were below 1 mg per person per day. These data are highly relevant for comparing decentralised treatment options with existing end-of-pipe treatments, for feeding into risk assessments and for design purposes.
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| 7. |
- Eriksson, Eva, 1973-, et al.
(författare)
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Substance flow analysis and source mapping of chemical UV-filters
- 2008
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Ingår i: Water, Air & Soil Pollution: Focus. - : Springer Science and Business Media LLC. - 1567-7230 .- 1573-2940. ; 8:5-6, s. 473-484
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Tidskriftsartikel (refereegranskat)abstract
- Chemical ultraviolet (UV)-filters are used in sunscreens to protect the skin from harmful UV radiation which may otherwise cause sunburns and skin cancer. Commonly used chemical UV-filters are known to cause endocrine disrupting effects in both aquatic and terrestrial animals as well as in human skin cells. Here, source mapping and substance flow analysis were applied to find the sources of six UV-filters (oxybenzone, avobenzone, 4-methylbenzylidene camphor, octyl methoxycinnamate, octyl dimethyl PABA and homosalate) and to identify the most dominant flows of these substances in Denmark. Urban water, composed of wastewater and surface waters, was found to be the primary recipient of UV-filters, whereby wastewater received an estimated 8.5–65 tonnes and surface waters received 7.1–51 tonnes in 2005. In wastewater treatment plants, their sorption onto sludge is perceived to be an important process and presence in effluents can be expected due to a lack of biodegradability. In addition, the use of UV-filters is expected to continue to increase significantly. Not all filters (e.g., octyl dimethyl PABA and homosalate) are used in Denmark. For example, 4-MBC is mainly associated with self-tanning liquids and private import of sunscreens.
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| 8. |
- Eriksson, Eva, 1973-, et al.
(författare)
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Substance flow analysis of parabens in Denmark complemented with a survey of presence and frequency in various commodities
- 2008
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Ingår i: Journal of Hazardous Materials. - : Elsevier BV. - 0304-3894 .- 1873-3336. ; 156:1-3, s. 240-259
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Tidskriftsartikel (refereegranskat)abstract
- Parabens are commonly used as preservatives due to anti-bactericidal and anti-fungicidal properties and they are ubiquitously present in personal care products, pharmaceuticals, food, industrial and domestic commodities. They are suspected of causing endocrine disrupting effects to aquatic organisms and adverse effects in humans and, thus, it is highly relevant to identify and quantify their sources and transportation pathways in the urban environment. Here a substance flow analysis (SFA) was performed in order to map and comprehend the substances’ flow on a national basis. Many household commodities were found to contain parabens; cleaning detergents, slimy toys, and water-based paint. The presence and concentration of parabens are regulated in cosmetics and food. Use of parabens in pharmaceuticals as excipients is documented in Denmark. The import of parabens is increasing; although the number of industrial parabens containing commodities is decreasing and manufacturer reports phase-out of parabens. The vast majority of the paraben containing commodities has a durability of 18–30 months, thus the average lifetime of the paraben stock is perceived to be limited. The inflow was ca. 154 tonnes via pure chemicals and 7.2–73 tonnes via commodities in 2004. This corresponds to an average wastewater concentration of 640–900 μg/L, when excluding discharge to solid waste, soil, biodegradation and metabolism. This is in the same order of magnitudes as can be found in industrial wastewater but higher than that seen in domestic wastewater. The data needed for the SFA is sparse, dispersed, and difficult to access and associated with a great deal of uncertainty.
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| 9. |
- Jacobsson, Erik, et al.
(författare)
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Peptide ion channel toxins from the bootlace worm, the longest animal on Earth
- 2018
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Ingår i: Scientific Reports. - : Nature Publishing Group. - 2045-2322. ; 8
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Tidskriftsartikel (refereegranskat)abstract
- Polypeptides from animal venoms have found important uses as drugs, pharmacological tools, and within biotechnological and agricultural applications. We here report a novel family of cystine knot peptides from nemertean worms, with potent activity on voltage-gated sodium channels. These toxins, named the alpha-nemertides, were discovered in the epidermal mucus of Lineus longissimus, the 'bootlace worm' known as the longest animal on earth. The most abundant peptide, the 31-residue long alpha-1, was isolated, synthesized, and its 3D NMR structure determined. Transcriptome analysis including 17 species revealed eight alpha-nemertides, mainly distributed in the genus Lineus. alpha-1 caused paralysis and death in green crabs (Carcinus maenas) at 1 mu g/kg (similar to 300 pmol/kg). It showed profound effect on invertebrate voltage-gated sodium channels (e.g. Blattella germanica Na(v)1) at low nanomolar concentrations. Strong selectivity for insect over human sodium channels indicates that a-nemertides can be promising candidates for development of bioinsecticidal agents.
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| 10. |
- Mikkelsen, Peter Steen, et al.
(författare)
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Monitoring, chemical fate modelling and uncertainty assessment in combination : a tool for evaluating emission control scenarios for micropollutants in stormwater systems
- 2012
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Ingår i: WSUD 2012 - 7th international conference on water sensitive urban design: building the water sensitive community. - 9780858258952
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Konferensbidrag (refereegranskat)abstract
- Stormwater discharges can represent significant sources of micropollutants (MP), including heavy metals and xenobiotic organic compounds that may pose a toxicity risk to aquatic ecosystems. Control of stormwater quality and reduction of MP loads is therefore necessary for a sustainable stormwater management in urban areas, but it is strongly hampered by the general lack of field data on these substances. A framework for combining field monitoring campaigns with dynamic MP modelling tools and statistical methods for uncertainty analysis was hence developed to estimate MP fluxes and fate in stormwater runoff and treatment systems under sparse data conditions.The framework was applied to an industrial/residential area in the outskirts of Copenhagen (Denmark), where stormwater is discharged in a separate channel system discharging to a wet detention pond. Analysis of economic activities and GIS data on land usage allowed characterizing the catchment and identifying the major potential sources of stormwater MP. Monitoring of the pond inlet and outlet, as well as sediment analyses, allowed assessing the current situation and highlighted potential risks for the downstream surface water environment. The collected data was used in combination with an integrated dynamic MP fate model to estimate the MP fluxes in the catchment and the MP fate in the pond over a 10-year period. The model was also used to evaluate the potential effects of anticipated future climate changes as well as different scenarios for reduction of MP emissions while considering the uncertainty of the model predictions.
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