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Sökning: WFRF:(Falck Ytter T)

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  • Jones, E. J. H., et al. (författare)
  • Eurosibs : Towards robust measurement of infant neurocognitive predictors of autism across Europe
  • 2019
  • Ingår i: Infant Behavior and Development. - 0163-6383 .- 1879-0453. ; 57
  • Tidskriftsartikel (refereegranskat)abstract
    • Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that affects social communication skills and flexible behaviour. Developing new treatment approaches for ASD requires early identification of the factors that influence later behavioural outcomes. One fruitful research paradigm has been the prospective study of infants with a first degree relative with ASD, who have around a 20% likelihood of developing ASD themselves. Early findings have identified a range of candidate neurocognitive markers for later ASD such as delayed attention shifting or neural responses to faces, but given the early stage of the field most sample sizes are small and replication attempts remain rare. The Eurosibs consortium is a European multisite neurocognitive study of infants with an older sibling with ASD conducted across nine sites in five European countries. In this manuscript, we describe the selection and standardization of our common neurocognitive testing protocol. We report data quality assessments across sites, showing that neurocognitive measures hold great promise for cross-site consistency in diverse populations. We discuss our approach to ensuring robust data analysis pipelines and boosting future reproducibility. Finally, we summarise challenges and opportunities for future multi-site research efforts.
  • Bartl-Pokorny, K. D., et al. (författare)
  • Eye Tracking in Basic Research and Clinical Practice
  • 2013
  • Ingår i: Klinische Neurophysiologie. - 1434-0275 .- 1439-4081. ; 44:3, s. 193-198
  • Tidskriftsartikel (refereegranskat)abstract
    • Eye tracking is a non-invasive technique based on infrared video technology that is used to analyse eye movements. Such analyses might provide insights into perceptual and cognitive capacities. It is a method widely used in various disciplines, such as ophthalmology, neurology, psychiatry and neuropsychology for basic science, but also clinical practice. For example, recent studies on children who were later diagnosed with autism spectrum disorders revealed early abnormal eye movement patterns in socio-communicative settings; children with dyslexia appeared also to have peculiar eye movement patterns, expressed in longer fixation durations and smaller saccades while reading. Current research using eye tracking systems in combination with neurophysiological and brain imaging techniques will add to a better understanding of cognitive, linguistic and socio-communicative development and in the near future possibly also lead to a broader clinical application of this method.
  • Bolte, S., et al. (författare)
  • How can clinicians detect and treat autism early? Methodological trends of technology use in research
  • 2016
  • Ingår i: Acta Paediatrica. - 0803-5253 .- 1651-2227. ; 105:2, s. 137-144
  • Forskningsöversikt (övrigt vetenskapligt)abstract
    • We reviewed original research papers that used quantifiable technology to detect early autism spectrum disorder (ASD) and identified 376 studies from 34 countries from 1965 to 2013. Publications have increased significantly since 2000, with most coming from the USA. Electroencephalogram, magnetic resonance imaging and eye tracking were the most frequently used technologies. Conclusion: The use of quantifiable technology to detect early ASD has increased in recent decades, but has had limited impact on early detection and treatment. Further scientific developments are anticipated, and we hope that they will increasingly be used in clinical practice for early ASD screening, diagnosis and intervention.
  • Falck-Ytter, T, et al. (författare)
  • Eye tracking in early autism research
  • 2013
  • Ingår i: Journal of neurodevelopmental disorders. - 1866-1947. ; 5:1, s. 28
  • Tidskriftsartikel (refereegranskat)
  • Tammimies, K, et al. (författare)
  • Quo Vadis clinical genomics of ASD?
  • 2016
  • Ingår i: Autism : the international journal of research and practice. - 1461-7005. ; 20:3, s. 259-261
  • Tidskriftsartikel (övrigt vetenskapligt)
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