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Olaparib Monotherapy in Patients With Advanced Cancer and a Germline BRCA1/2 Mutation.

Kaufman, Bella (author)
Shapira-Frommer, Ronnie (author)
Schmutzler, Rita K (author)
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Audeh, M William (author)
Friedlander, Michael (author)
Balmaña, Judith (author)
Mitchell, Gillian (author)
Fried, Georgeta (author)
Stemmer, Salomon M (author)
Hubert, Ayala (author)
Rosengarten, Ora (author)
Steiner, Mariana (author)
Loman, Niklas (author)
Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine
Bowen, Karin (author)
Fielding, Anitra (author)
Domchek, Susan M (author)
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 (creator_code:org_t)
2015
2015
English.
In: Journal of Clinical Oncology. - 1527-7755. ; 33:3, s. 134-244
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Olaparib is an oral poly (ADP-ribose) polymerase inhibitor with activity in germline BRCA1 and BRCA2 (BRCA1/2) -associated breast and ovarian cancers. We evaluated the efficacy and safety of olaparib in a spectrum of BRCA1/2-associated cancers.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

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