SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Forsander G.) ;lar1:(oru)"

Sökning: WFRF:(Forsander G.) > Örebro universitet

  • Resultat 1-3 av 3
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Bybrant, M. C., et al. (författare)
  • Celiac disease can be predicted by high levels of tissue transglutaminase antibodies in children and adolescents with type 1 diabetes
  • 2021
  • Ingår i: Pediatric Diabetes. - : Hindawi Limited. - 1399-543X .- 1399-5448. ; 22:3, s. 417-424
  • Tidskriftsartikel (refereegranskat)abstract
    • Objectives Children with type 1 diabetes (T1D) are not included in guidelines regarding diagnosis criteria for celiac disease (CD) without a diagnostic biopsy, due to lack of data. We explored whether tissue transglutaminase antibodies (anti-tTG) that were >= 10 times the upper limit of normal (10x ULN) predicted CD in T1D. Methods Data from the Swedish prospective Better Diabetes Diagnosis study was used, and 2035 children and adolescents with T1D diagnosed between 2005-2010 were included. Of these, 32 had been diagnosed with CD before T1D. The children without CD were repeatedly screened for CD using anti-tTG antibodies of immunoglobulin type A. In addition, their human leukocyte antigen (HLA) were genotyped. All children with positive anti-tTG were advised to undergo biopsy. Biopsies were performed on 119 children and graded using the Marsh-Oberhuber classification. Results All of the 60 children with anti-tTG >= 10x ULN had CD verified by biopsies. The degree of mucosal damage correlated with anti-tTG levels. Among 2003 screened children, 6.9% had positive anti-tTG and 5.6% were confirmed CD. The overall CD prevalence, when including the 32 children with CD before T1D, was 7.0% (145/2035). All but one of the children diagnosed with CD had HLA-DQ2 and/or DQ8. Conclusions As all screened children and adolescents with T1D with tissue transglutaminase antibodies above 10 times the positive value 10x ULN had CD, we propose that the guidelines for diagnosing CD in screened children, when biopsies can be omitted, should also apply to children and adolescents with T1D as a noninvasive method.
  •  
2.
  •  
3.
  • Lindehammer, Sabina, et al. (författare)
  • Temporal trends of HLA genotype frequencies of type 1 diabetes patients in Sweden from 1986 to 2005 suggest altered risk
  • 2008
  • Ingår i: Acta Diabetologica. - : Springer Science and Business Media LLC. - 0940-5429 .- 1432-5233. ; 45:4, s. 231-5
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study was to compare the frequency of human leukocyte antigen (HLA) genotypes in 1-18-year-old patients with type 1 diabetes newly diagnosed in 1986-1987 (n = 430), 1996-2000 (n = 342) and in 2003-2005 (n = 171). We tested the hypothesis that the HLA DQ genotype distribution changes over time. Swedish type 1 diabetes patients and controls were typed for HLA using polymerase chain reaction amplification and allele specific probes for DQ A1* and B1* alleles. The most common type 1 diabetes HLA DQA1*-B1*genotype 0501-0201/0301-0302 was 36% (153/430) in 1986-1987 and 37% (127/342) in 1996-2000, but decreased to 19% (33/171) in 2003-2005 (P \ 0.0001). The 0501-0201/0501-0201 genotype increased from 1% in 1986-1987 to 7% in 1996-2000 (P = 0.0047) and to 5% in 2003-2005 (P > 0.05). This study in 1-18-year-old Swedish type 1 diabetes patients supports the notion that there is a temporal change in HLA risk.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-3 av 3
Typ av publikation
tidskriftsartikel (2)
konferensbidrag (1)
Typ av innehåll
refereegranskat (3)
Författare/redaktör
Lernmark, Åke (2)
Carlsson, Annelie (2)
Åkesson, Karin (2)
Ivarsson, Sten A. (2)
Forsander, Gun, 1951 (2)
Särnblad, Stefan, 19 ... (2)
visa fler...
Arvidsson, C. G. (2)
Johansson, C. (1)
Sjöblad, Sture (1)
Lindblad, Bengt (1)
Kockum, K (1)
Persson, M (1)
Larsson, Karin (1)
Holmberg, E. (1)
Cilio, Corrado (1)
Lynch, Kristian (1)
Hanås, R (1)
Ivarsson, Sten (1)
Ludvigsson, Jonas F. ... (1)
Tuvemo, Torsten (1)
Lindgren, Marie (1)
Ludvigsson, Johnny, ... (1)
Ludvigsson, Johnny (1)
Marcus, C (1)
Marcus, Claude (1)
Westphal, Otto, 1935 (1)
Åman, Jan, 1948- (1)
Gustafsson, Anna (1)
Nilsson, Anna (1)
Carlsson, E. (1)
Neiderud, Jan (1)
Larsson, Helena (1)
Neiderud, J (1)
Elding Larsson, Hele ... (1)
Forsander, Gun (1)
Lindblad, Birgitta E ... (1)
Thalme, B (1)
Lindehammer, Sabina (1)
Samuelsson, Ulf, 195 ... (1)
Jönsson, B.A. (1)
Örtqvist, Eva (1)
Bybrant, M. C. (1)
Uden, E. (1)
Frederiksen, F. (1)
Gustafsson, A. L. (1)
Fureman, A. L. (1)
Lycka, A. P. (1)
Sarnblad, S. (1)
Oortqvist, E. (1)
Cerqueiro Bybrant, M ... (1)
visa färre...
Lärosäte
Örebro universitet  (3)Ta bort avgränsningen
Göteborgs universitet (2)
Linköpings universitet (2)
Lunds universitet (2)
Karolinska Institutet (2)
Uppsala universitet (1)
visa fler...
Jönköping University (1)
visa färre...
Språk
Engelska (3)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (3)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy