SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Franke Barbara) ;hsvcat:5"

Sökning: WFRF:(Franke Barbara) > Samhällsvetenskap

  • Resultat 1-2 av 2
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Ghirardi, Laura, et al. (författare)
  • Genetic and environmental contribution to the overlap between ADHD and ASD trait dimensions in young adults : a twin study
  • 2019
  • Ingår i: Psychological Medicine. - : Cambridge University Press. - 0033-2917 .- 1469-8978. ; 49:10, s. 1713-1721
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Traits of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are strongly associated in children and adolescents, largely due to genetic factors. Less is known about the phenotypic and aetiological overlap between ADHD and ASD traits in adults.METHODS: We studied 6866 individuals aged 20-28 years from the Swedish Study of Young Adult Twins. Inattention (IA) and hyperactivity/impulsivity (HI) were assessed using the WHO Adult ADHD Self-Report Scale-V1.1. Repetitive and restricted behaviours (RRB) and social interaction and communication (SIC) were assessed using the Autism-Tics, ADHD, and other Comorbidities inventory. We used structural equation modelling to decompose covariance between these ADHD and ASD trait dimensions into genetic and shared/non-shared environmental components.RESULTS: At the phenotypic level, IA was similarly correlated with RRB (r = 0.33; 95% Confidence Interval (CI) 0.31-0.36) and with SIC (r = 0.32; 95% CI 0.29-0.34), whereas HI was more strongly associated with RRB (r = 0.38; 95% CI 0.35-0.40) than with SIC (r = 0.24; 95% CI 0.21-0.26). Genetic and non-shared environmental effects accounted for similar proportions of the phenotypic correlations, whereas shared environmental effects were of minimal importance. The highest genetic correlation was between HI and RRB (r = 0.56; 95% 0.46-0.65), and the lowest was between HI and SIC (r = 0.33; 95% CI 0.23-0.43).CONCLUSIONS: We found evidence for dimension-specific phenotypic and aetiological overlap between ADHD and ASD traits in adults. Future studies investigating mechanisms underlying comorbidity between ADHD and ASD may benefit from exploring several symptom-dimensions, rather than considering only broad diagnostic categories.
  •  
2.
  • Thompson, Paul M., et al. (författare)
  • The ENIGMA Consortium : large-scale collaborative analyses of neuroimaging and genetic data
  • 2014
  • Ingår i: BRAIN IMAGING BEHAV. - : Springer Science and Business Media LLC. - 1931-7557 .- 1931-7565. ; 8:2, s. 153-182
  • Tidskriftsartikel (refereegranskat)abstract
    • The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from over 12,826 subjects. In addition, data from 12,171 individuals were provided by the CHARGE consortium for replication of findings, in a total of 24,997 subjects. By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ENIGMA's first project was a genome-wide association study identifying common variants in the genome associated with hippocampal volume or intracranial volume. Continuing work is exploring genetic associations with subcortical volumes (ENIGMA2) and white matter microstructure (ENIGMA-DTI). Working groups also focus on understanding how schizophrenia, bipolar illness, major depression and attention deficit/hyperactivity disorder (ADHD) affect the brain. We review the current progress of the ENIGMA Consortium, along with challenges and unexpected discoveries made on the way.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-2 av 2
Typ av publikation
tidskriftsartikel (2)
Typ av innehåll
refereegranskat (2)
Författare/redaktör
Franke, Barbara (2)
Landén, Mikael, 1966 (1)
Liberg, Benny (1)
Ekman, Carl-Johan (1)
Ching, Christopher R ... (1)
Agartz, Ingrid (1)
visa fler...
Alda, Martin (1)
Brouwer, Rachel M (1)
Cannon, Dara M (1)
Hajek, Tomas (1)
Malt, Ulrik F (1)
McDonald, Colm (1)
Melle, Ingrid (1)
Westlye, Lars T (1)
Thompson, Paul M (1)
Andreassen, Ole A (1)
Nyberg, Lars (1)
van der Wee, Nic J. (1)
Larsson, Henrik, 197 ... (1)
Taylor, Mark J. (1)
Wang, Lei (1)
Pettersson, Erik (1)
Coppola, Giovanni (1)
Weale, Michael E. (1)
Nilsson, Lars-Göran (1)
de Geus, Eco J. C. (1)
Martin, Nicholas G. (1)
Boomsma, Dorret I. (1)
Hardy, John (1)
Almeida, Jorge (1)
Djurovic, Srdjan (1)
Meyer-Lindenberg, An ... (1)
Ramasamy, Adaikalava ... (1)
Thalamuthu, Anbupala ... (1)
Cichon, Sven (1)
Trost, Sarah (1)
Laje, Gonzalo (1)
Pfennig, Andrea (1)
Bauer, Michael (1)
Rietschel, Marcella (1)
Schofield, Peter R (1)
McMahon, Francis J (1)
Deary, Ian J (1)
Ghirardi, Laura (1)
Kuja-Halkola, Ralf (1)
Mattheisen, Manuel (1)
Smith, Colin (1)
Fernández, Guillen (1)
Freitag, Christine M (1)
Cantor, Rita M (1)
visa färre...
Lärosäte
Karolinska Institutet (2)
Göteborgs universitet (1)
Umeå universitet (1)
Stockholms universitet (1)
Örebro universitet (1)
Språk
Engelska (2)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (2)
Samhällsvetenskap (2)Ta bort avgränsningen

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy