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Variation in pain r...
Variation in pain related to systemic lupus erythematosus (SLE): a 7-year follow-up study
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- Waldheim, E. (författare)
- Karolinska Institute,Karolinska Institutet,Karolinska Inst, Sweden
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- Ajeganova, S. (författare)
- Karolinska Institute,Karolinska Institutet,Karolinska Inst, Sweden
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- Bergman, Stefan (författare)
- Lund University,Lunds universitet,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Primary Health Care Unit, Department of Public Health and Community Medicine, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Spenshult Research and Development Center, Halmstad, Sweden; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund, Sweden,Univ Gothenburg, Sweden; Spenshult Res and Dev Ctr, Sweden; Lund Univ, Sweden,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Frostegard, J. (författare)
- Karolinska Institute,Karolinska Institutet,Karolinska Inst, Sweden
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- Welin, Elisabet, 1960- (författare)
- Linköping University,Karolinska Institute,Linköpings universitet,Karolinska Institutet,Avdelningen för omvårdnad,Medicinska fakulteten,Region Östergötland, Reumatologiska kliniken i Östergötland,Karolinska Inst, Sweden
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(creator_code:org_t)
- 2018-04-14
- 2018
- Engelska.
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Ingår i: Clinical Rheumatology. - : Springer Science and Business Media LLC. - 0770-3198 .- 1434-9949. ; 37:7, s. 1825-1834
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Abstract
Ämnesord
Stäng
- We have previously shown that most patients with systemic lupus erythematosus (SLE) reported low degree of SLE-related pain. However, 24% of the patients reported high degree of SLE-related pain, more fatigue, anxiety and depression, and worse health-related quality of life (HRQoL). To explore SLE-related pain, the presence of long-standing widespread pain, and patient-reported outcomes (PROs) after 7 years. Sixty-four out of 84 patients participated in a 7-year follow-up of the original survey and completed the same questionnaires answered at inclusion: pain (VAS 100 mm), fatigue (MAF), HRQoL (SF-36), anxiety and depression (HADS), and, if appropriate, a pain-drawing. Differences between inclusion and follow-up (change) were calculated. The patients with a low degree of SLE-related pain at inclusion reported no changes at follow-up in pain and PROs except for worsening in physical function in SF-36, median change (IQR) 0 (- 10 to 5), p = 0.024. Half of the patients with high degree of pain at inclusion reported decreased pain at follow-up, median change (IQR) 45 (35 to 65), p = 0.021; fatigue, 8 (8 to 17), p = 0.018; anxiety, 4 (1 to 4), p = 0.035; and depression, 4 (2 to 5), p = 0.018 and improvements in most dimensions of SF-36. The remaining half of the patients reported no changes regarding pain and PROs except for a worsening in vitality in SF-36, 20 (15 to 35), p = 0.0018. All patients with remaining high level of pain indicated long-standing widespread pain. After 7 years, a subgroup of patients with SLE reported remaining high level of SLE-related pain and a high symptom burden, including long-standing widespread pain. Such patients require more observant attention to receive appropriate treatment.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Nyckelord
- Anxiety
- Depression
- Fatigue
- Health-related quality of life
- Pain
- SLE
- quality-of-life
- sf-36 health survey
- disease-activity
- rheumatoid-arthritis
- musculoskeletal pain
- depression scale
- hospital
- anxiety
- unmet needs
- fatigue
- patient
- Rheumatology
- ice dd
- 1983
- pain
- v17
- p45
- Anxiety
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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