SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Gareth Evans D.) srt2:(2015-2019);lar1:(uu);lar1:(umu)"

Sökning: WFRF:(Gareth Evans D.) > (2015-2019) > Uppsala universitet > Umeå universitet

  • Resultat 1-3 av 3
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Bentham, James, et al. (författare)
  • A century of trends in adult human height
  • 2016
  • Ingår i: eLIFE. - 2050-084X. ; 5
  • Tidskriftsartikel (refereegranskat)abstract
    • Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.522.7) and 16.5 cm (13.319.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
  •  
2.
  •  
3.
  • Vigorito, Elena, et al. (författare)
  • Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
  • 2016
  • Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 11:7
  • Tidskriftsartikel (refereegranskat)abstract
    • Population-based genome wide association studies have identified a locus at 9p22.2 associated with ovarian cancer risk, which also modifies ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. We conducted fine-scale mapping at 9p22.2 to identify potential causal variants in BRCA1 and BRCA2 mutation carriers. Genotype data were available for 15,252 (2,462 ovarian cancer cases) BRCA1 and 8,211 (631 ovarian cancer cases) BRCA2 mutation carriers. Following genotype imputation, ovarian cancer associations were assessed for 4,873 and 5,020 SNPs in BRCA1 and BRCA2 mutation carriers respectively, within a retrospective cohort analytical framework. In BRCA1 mutation carriers one set of eight correlated candidate causal variants for ovarian cancer risk modification was identified (top SNP rs10124837, HR: 0.73, 95% CI: 0.68 to 0.79, p-value 2x 10-16). These variants were located up to 20 kb upstream of BNC2. In BRCA2 mutation carriers one region, up to 45 kb upstream of BNC2, and containing 100 correlated SNPs was identified as candidate causal (top SNP rs62543585, HR: 0.69, 95% CI: 0.59 to 0.80, p-value 1.0 x 10-6). The candidate causal in BRCA1 mutation carriers did not include the strongest associated variant at this locus in the general population. In sum, we identified a set of candidate causal variants in a region that encompasses the BNC2 transcription start site. The ovarian cancer association at 9p22.2 may be mediated by different variants in BRCA1 mutation carriers and in the general population. Thus, potentially different mechanisms may underlie ovarian cancer risk for mutation carriers and the general population.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-3 av 3
Typ av publikation
tidskriftsartikel (3)
Typ av innehåll
refereegranskat (3)
Författare/redaktör
Peeters, Petra H (2)
Overvad, Kim (2)
Kaaks, Rudolf (2)
Boeing, Heiner (2)
Trichopoulou, Antoni ... (2)
Norat, Teresa (2)
visa fler...
Riboli, Elio (2)
Joffres, Michel (2)
McKee, Martin (2)
Salomaa, Veikko (2)
Lundqvist, Annamari (2)
Giwercman, Aleksande ... (2)
Wade, Alisha N. (2)
Cooper, Cyrus (2)
Hardy, Rebecca (2)
Sunyer, Jordi (2)
Brenner, Hermann (2)
Claessens, Frank (2)
Craig, Cora L. (2)
Sjostrom, Michael (2)
Adams, Robert (2)
Thijs, Lutgarde (2)
Staessen, Jan A (2)
Farzadfar, Farshad (2)
Geleijnse, Johanna M ... (2)
Guessous, Idris (2)
Jonas, Jost B. (2)
Kasaeian, Amir (2)
Khader, Yousef Saleh (2)
Khang, Young-Ho (2)
Lotufo, Paulo A. (2)
Malekzadeh, Reza (2)
Mensink, Gert B. M. (2)
Mohan, Viswanathan (2)
Nagel, Gabriele (2)
Qorbani, Mostafa (2)
Rivera, Juan A. (2)
Sepanlou, Sadaf G. (2)
Szponar, Lucjan (2)
Alkerwi, Ala'a (2)
Bjertness, Espen (2)
Kengne, Andre P. (2)
McGarvey, Stephen T. (2)
Schutte, Aletta E. (2)
Shiri, Rahman (2)
Topor-Madry, Roman (2)
Branca, Francesco (2)
Damasceno, Albertino (2)
Rosengren, Annika (2)
Michaelsen, Kim F (2)
visa färre...
Lärosäte
Umeå universitet  (3)Ta bort avgränsningen
Uppsala universitet  (3)Ta bort avgränsningen
Göteborgs universitet (1)
Luleå tekniska universitet (1)
Lunds universitet (1)
Karolinska Institutet (1)
visa fler...
Högskolan Dalarna (1)
visa färre...
Språk
Engelska (3)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (3)
År
2016 (3)

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy