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The Antibody Societ...
The Antibody Society's antibody validation webinar series
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- Voskuil, Jan L. A. (författare)
- Aeonian Biotech Ltd, Marcham OX13 6PH, England.
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- Bandrowski, Anita (författare)
- Univ Calif San Diego, Ctr Res Biol Syst, La Jolla, CA 92093 USA.
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- Begley, C. Glenn (författare)
- BioCurate, Parkville, Vic, Australia.
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visa fler...
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- Bradbury, Andrew R. M. (författare)
- Specifica Inc, Santa Fe, NM USA.
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- Chalmers, Andrew D. (författare)
- Univ Bath, Dept Biol & Biochem, Bath, Avon, England.;CiteAb, Bath, Avon, England.
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- Gomes, Aldrin V. (författare)
- Univ Calif Davis, Dept Neurobiol Physiol & Behav, Davis, CA 95616 USA.
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- Hardcastle, Travis (författare)
- Waterbeach, Horizon Discovery, Cambridge, England.
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- Lund-Johansen, Fridtjof (författare)
- Oslo Univ Hosp, Dept Immunol, Oslo, Norway.
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- Plueckthun, Andreas (författare)
- Univ Zurich, Dept Biochem, Zurich, Switzerland.
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- Roncador, Giovanna (författare)
- Spanish Natl Canc Res Ctr, Monoclonal Antibody Unit, Madrid, Spain.
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- Solache, Alejandra (författare)
- Abcam Plc, Discovery Dr,Biomed Campus, Cambridge, England.
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- Taussig, Michael J. (författare)
- Cambridge Prot Arrays Ltd, Babraham Res Campus, Cambridge, England.
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- Trimmer, James S. (författare)
- Univ Calif Davis, Sch Med, Dept Physiol & Membrane Biol, Davis, CA 95616 USA.
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- Williams, Cecilia, Professor, 1969- (författare)
- Karolinska Institutet,KTH,Science for Life Laboratory, SciLifeLab,Proteinvetenskap,Karolinska Inst, Dept Biosci & Nutr, Huddinge, Sweden.
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- Goodman, Simon L. (författare)
- Antibody Soc Inc, Framingham, MA USA.
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Aeonian Biotech Ltd, Marcham OX13 6PH, England Univ Calif San Diego, Ctr Res Biol Syst, La Jolla, CA 92093 USA. (creator_code:org_t)
- 2020-08-04
- 2020
- Engelska.
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Ingår i: mAbs. - : Informa UK Limited. - 1942-0862 .- 1942-0870. ; 12:1
- Relaterad länk:
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https://doi.org/10.1...
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https://www.tandfonl...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- In the wake of the reproducibility crisis and numerous discussions on how commercially available antibodies as research tool contribute to it, The Antibody Society developed a series of 10 webinars to address the issues involved. The webinars were delivered by speakers with both academic and commercial backgrounds. This report highlights the problems, and offers solutions to help the scientific community appropriately identify the right antibodies and to validate them for their research and development projects. Despite the various solutions proposed here, they must be applied on a case-by-case basis. Each antibody must be verified based on the content of the product sheet, and subsequently through experimentation to confirm integrity, specificity and selectivity. Verification needs to focus on the precise application and tissue/cell type for which the antibody will be used, and all verification data must be reported openly. The various approaches discussed here all have caveats, so a combination of solutions must be considered.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
Nyckelord
- Antibody specificity
- antibody selectivity
- specific antibodies
- selective antibodies
- reproducibility
- recombinant antibodies
- monoclonal antibodies
- polyclonal antibodies
- peptide antibodies
- antibody validation
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mAbs
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- Av författaren/redakt...
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Voskuil, Jan L. ...
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Bandrowski, Anit ...
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Begley, C. Glenn
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Bradbury, Andrew ...
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Chalmers, Andrew ...
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Gomes, Aldrin V.
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visa fler...
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Hardcastle, Trav ...
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Lund-Johansen, F ...
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Plueckthun, Andr ...
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Roncador, Giovan ...
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Solache, Alejand ...
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Taussig, Michael ...
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Trimmer, James S ...
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Williams, Cecili ...
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Goodman, Simon L ...
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Kungliga Tekniska Högskolan
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