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Sökning: WFRF:(Gronberg H) > Teknik

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1.
  • Bulten, W, et al. (författare)
  • Artificial intelligence for diagnosis and Gleason grading of prostate cancer: the PANDA challenge
  • 2022
  • Ingår i: Nature medicine. - : Springer Science and Business Media LLC. - 1546-170X .- 1078-8956. ; 28:21, s. 154-
  • Tidskriftsartikel (refereegranskat)abstract
    • Artificial intelligence (AI) has shown promise for diagnosing prostate cancer in biopsies. However, results have been limited to individual studies, lacking validation in multinational settings. Competitions have been shown to be accelerators for medical imaging innovations, but their impact is hindered by lack of reproducibility and independent validation. With this in mind, we organized the PANDA challenge—the largest histopathology competition to date, joined by 1,290 developers—to catalyze development of reproducible AI algorithms for Gleason grading using 10,616 digitized prostate biopsies. We validated that a diverse set of submitted algorithms reached pathologist-level performance on independent cross-continental cohorts, fully blinded to the algorithm developers. On United States and European external validation sets, the algorithms achieved agreements of 0.862 (quadratically weighted κ, 95% confidence interval (CI), 0.840–0.884) and 0.868 (95% CI, 0.835–0.900) with expert uropathologists. Successful generalization across different patient populations, laboratories and reference standards, achieved by a variety of algorithmic approaches, warrants evaluating AI-based Gleason grading in prospective clinical trials.
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2.
  • Oelsner, G., et al. (författare)
  • Underdamped Josephson junction as a switching current detector
  • 2013
  • Ingår i: Applied Physics Letters. - : AIP Publishing. - 0003-6951 .- 1077-3118. ; 103:14
  • Tidskriftsartikel (refereegranskat)abstract
    • We demonstrate the narrow switching distribution of an underdamped Josephson junction from the zero to the finite voltage state at millikelvin temperatures. We argue that such junctions can be used as ultrasensitive detectors of the single photons in the GHz range, operating close to the quantum limit: a given initial (zero voltage) state can be driven by an incoming signal to the finite voltage state. The width of the switching distribution at a nominal temperature of about T = 10 mK was 4.5 nA, which corresponds to an effective noise temperature of the device below 60 mK. (C) 2013 AIP Publishing LLC.
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3.
  • Grigoras, K., et al. (författare)
  • Qubit-Compatible Substrates With Superconducting Through-Silicon Vias
  • 2022
  • Ingår i: IEEE Transactions on Quantum Engineering. - 2689-1808. ; 3
  • Tidskriftsartikel (refereegranskat)abstract
    • We fabricate and characterize superconducting through-silicon vias and electrodes suitable for superconducting quantum processors. We measure internal quality factors of a million for test resonators excited at single-photon levels, on chips with superconducting vias used to stitch ground planes on the front and back sides of the chips. This resonator performance is on par with the state of the art for silicon-based planar solutions, despite the presence of vias. Via stitching of ground planes is an important enabling technology for increasing the physical size of quantum processor chips, and is a first step toward more complex quantum devices with three-dimensional integration.
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