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Sökning: WFRF:(Gustavsson Leif)

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1.
  • Landin-Olsson, Mona, et al. (författare)
  • Immunoreactive trypsin(Ogen) in the sera of children with recent-onset insulin-dependent diabetes and matched controls
  • 1990
  • Ingår i: Pancreas. - : Ovid Technologies (Wolters Kluwer Health). - 0885-3177. ; 5:3, s. 241-247
  • Tidskriftsartikel (refereegranskat)abstract
    • To evaluate the exocrine pancreatic function at the time of diagnosis of insulin-dependent diabetes mellitus, we determined immunoreactive an-odal and cathodal trypsin(ogen) levels in sera from almost all children (n = 375) 0-14 years of age in Sweden in whom diabetes developed during 1 year, and in sex-, age-, and geographically matched control subjects (n = 312). The median level of anodal trypsin(ogen) was 5 (quartile range, 3-7) µg/L in children with newly diagnosed diabetes, compared with a median level of 7 (quartile range, 4-8) µg/L in control subjects (p < 0.0001). Similarly, the median level of cathodal trypsin(ogen) was 8 (quartile range, 4-10) µg/L in children with diabetes, compared with a median level of 11 (quartile range, 7-15) µg/L in control subjects (p < 0.0001). The median of the individual ratios between cathodal and anodal trypsin(ogen) was 1.4 in the diabetic patients and 1.7 in the control children (p < 0.001). In a multivariate test, however, only the decrease in cathodal trypsin(ogen) concentration was associated with diabetes. The levels of trypsin(ogen)s did not correlate with levels of islet cell antibodies, present in 81% of the diabetic children. Several mechanisms may explain our findings, for example, similar pathogenetic factors may affect both the endocrine and exocrine pancreas simultaneously, a failing local trophic stimulation by insulin on the exocrine cells may decrease the trypsinogen production, and there may be an increased elimination of trypsin(ogen) because of higher filtration through the kidneys in the hyperglycemic state.
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2.
  • Aabrekk, S., et al. (författare)
  • Deliverable 2.2 Possible market strategies for one stop shops of renovation of single family house. : Report prepared for Nordic Innovation Centre
  • 2012
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • The document describes examples of missions, visions and strategies based on the potentialpiloting models defined in report 3.2. It is based on status of interest amongst thestakeholders, and the information, figures and challenges which were discussed in the reportD 2.1 Stakeholder interests. The different service models will request different missionsdepending on the stakeholder in charge of the model. Also visions and strategies could bedifferent depending on the composition of services (core business) offered within each pilot aswell as the additional services offered by sub suppliers and the network connected to the pilot.In the report D2.1 Stakeholders interests, the following 5 different piloting models aresuggested:Type 1 Joint venture of industry, retailers and contractorsType 2 Joint venture of construction/renovation, industry and architect/engineering companiesType 3 Complementary businesses expand their business into renovationType 4 Joint venture of type house producer, bank and home owner associationType 5 Energy/building consultant, real estate agent and financing institutions, e.g. bankIn this report we have described mission, vision and market strategies for 4 existing orproposed models; The Project Manager by Bolig Enøk, from Norway (type 1), ENRA concept(type 2) and K-Rauta & Rautia (type 3) from Finland, and ProjectLavenergi (type 2) fromDenmark. Cleantech by Dong Energy (type 3) from Denmark is also addressed, but notdescribed in detail. As there is no concrete examples representing two of the models fromD2.1 (types 4 and 5), we have made a theoretical exercise in developing mission, vision andmarket strategies for type 5 model, while type 4 is not handled.It may be concluded that there are commercial actors in different parts of the value chainwhich see an opportunity in developing different approaches of “one stop shops” for energyefficient holistic renovations. The concepts are still in a development phase and differ inrespect to how they are organised (as supply side). We may say that the pilots in the differentcountries also find inspiration from each other through this research project. Due to thecomplexity of a holistic renovation project, it is a prerequisite with good partnerships even inthe development phase. In all identified models there is however one main actor taking thelead and ownership to the business model.Independent of the business model the responsible company needs to make some strategicchoices. The starting point is the SWOT analysis which sums up all major challenges for therespective business model. How the strategies should be developed is described in this report.Although the main target group for this report is companies seeing an interest in developingbusiness models for renovation, we found some important issues identified in the SWOTanalysis which the authorities may influence including lack of interest in the market (need ofmore public attention through holistic campaigns), fragmented solutions (stop subsidisingsingle measures without a holistic plan), serious vs unserious companies (need of certificationsystems to build credibility), cost focus leads to limited renovation (need of subventionschemes for holistic retrofitting including tax deduction measures) and finally lack incompetence within companies (need of support to training and collaboration acrosscompanies).
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5.
  • Bonakdar, Farshid, 1977-, et al. (författare)
  • Cost-optimum analysis of building fabric renovation in a Swedish multi-story residential building
  • 2014
  • Ingår i: Energy and Buildings. - : Elsevier. - 0378-7788 .- 1872-6178. ; 84, s. 662-673
  • Tidskriftsartikel (refereegranskat)abstract
    • In this study, we analysed the cost-optimum level of building fabric elements renovation in a multi-story residential building. We calculated final energy use for space heating of the building considering a wide range of energy efficiency measures, for exterior walls, basement walls, attic floor and windows. Different extra insulation thicknesses for considered opaque elements and different U-values for new windows were used as energy efficiency measures. We calculated difference between the marginal saving of energy cost for space heating and the investment cost of implemented energy efficiency measures, in order to find the cost-optimum measure for each element. The implications of building lifespans, annual energy price increase and discount rate on the optimum measure were also analysed. The results of the analysis indicate that the contribution of energy efficiency measures to the final energy use reduces, significantly, by increasing the thickness of extra insulation and by reducing the U-value of new windows. We considered three scenarios of business as usual (BAU), intermediate and sustainability, considering different discount rates and energy price increase. The results of this analysis suggest that the sustainability scenario may offer, approximately, 100% increase in the optimum thickness of extra insulation compare to BAU scenario. However, the implication of different lifespans of 40, 50 or 60 years, on the optimum measure appears to be either negligible or very small, depending on the chosen scenario. We also calculated the corresponding U-value of the optimum measures in order to compare them with the current Swedish building code requirements and passive house criteria. The results indicate that all optimum measures meet the Swedish building code. None of the optimum measures, however, meet the passive house criteria in BAU scenario. This study suggests that the employed method of building renovation cost-optimum analyses can be also applied on new building construction to find the cost-optimum design from energy conservation point of view.
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6.
  • Bonakdar, Farshid, et al. (författare)
  • Implications of energy efficiency renovation measures for a Swedish residential building on cost, primary energy use and carbon dioxide emission
  • 2013
  • Ingår i: ECEEE Summer Study proceedings. - : European Council for an Energy Efficient Economy (ECEEE). - 9789198048223 ; , s. 1287-1296
  • Konferensbidrag (refereegranskat)abstract
    • Building sector accounts for 40% of total primary energy use in the EU. Measures to improve energy efficiency in existing buildings may reduce primary energy use and carbon dioxide (CO2) emission. In this study, we analysed the potential final energy savings for space heating and cost-effectiveness of different energy efficiency measures for a Swedish multi-story residential building from building owner perspective. The implications of the measures on primary energy use and CO2 emission were also explored. Building envelope elements were considered as energy efficiency measures. Required investment for energy efficiency measures per saved energy price was used as indication for the cost-effectiveness of energy renovation. We analysed three scenarios of energy renovation where the building is in its initial state, once with and then without renovation need for repair and maintenance purpose and the scenario for the current state of building. The current state of the building has some modification compared to the initial state. We performed sensitivity analysis to study the influence of economic parameters on the cost-effectiveness of energy efficiency measures. The results showed that the energy savings and cost-effectiveness of the measures depend on building characteristics, energy efficiency measures and the assumed economic parameters. Modelling of final energy use, before and after energy renovation, and its cost analysis showed that the considered energy efficiency measures were not economically profitable with the initial economic assumption (6% discount rate and 1.9% annual energy price increase during 50-year lifespan). For the renovation package of all energy efficiency measures, energy renovation appeared to be profitable when discount rate and annual energy price increase were 3% and 2.5% (or larger), respectively. Primary energy use and CO2 emission were reduced by 45 to 50% for the same package for the building with cogeneration-based district heating.
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8.
  • Börjesson, Pål, et al. (författare)
  • Biomass Transportation
  • 1996
  • Ingår i: Renewable Energy. - : Elsevier BV. - 0960-1481. ; 9:1-4, s. 1033-1036, s. 1033-1036
  • Tidskriftsartikel (refereegranskat)abstract
    • Extensive utilisation of logging residues, straw, and energy crops will lead to short transportation distances and thus low transportation costs. The average distance of transportation of biomass to a large-scale conversion plant, suitable for electricity or methanol production using 300 000 dry tonne biomass yearly, will be about 30 km in Sweden, if the conversion plant is located at the centre of the biomass production area. The estimated Swedish biomass potential of 430 PJ/yr is based on production conditions around 2015, assuming that 30% of the available arable land is used for energy crop production. With present production conditions, resulting in a biomass potential of 220 PJ/yr, the transportation distance is about 42 km. The cost of transporting biomass 30-42 km will be equivalent to 20-25% of the total biomass cost. The total energy efficiency of biomass production and transportation will be 95-97%, where the energy losses from transportation are about 20%. Biomass transportation will contribute less than 10% to the total NOx, CO, and HC emissions from biomass production, transportation, and conversion.
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9.
  • Börjesson, Pål, et al. (författare)
  • Future Production and Utilisation of Biomass in Sweden: Potentials and CO2 Mitigation
  • 1997
  • Ingår i: Biomass & Bioenergy. - 1873-2909 .- 0961-9534. ; 13:6, s. 399-412
  • Tidskriftsartikel (refereegranskat)abstract
    • Swedish biomass production potential could be increased significantly if new production methods, such as optimised fertilisation, were to be used. Optimised fertilisation on 25% of Swedish forest land and the use of stem wood could almost double the biomass potential from forestry compared with no fertilisation, as both logging residues and large quantities of excess stem wood not needed for industrial purposes could be used for energy purposes. Together with energy crops and straw from agriculture, the total Swedish biomass potential would be about 230 TWh/yr or half the current Swedish energy supply if the demand for stem wood for building and industrial purposes were the same as today. The new production methods are assumed not to cause any significant negative impact on the local environment. The cost of utilising stem wood produced with optimised fertilisation for energy purposes has not been analysed and needs further investigation. Besides replacing fossil fuels and, thus, reducing current Swedish CO2 emissions by about 65%, this amount of biomass is enough to produce electricity equivalent to 20% of current power production. Biomass-based electricity is produced preferably through co-generation using district heating systems in densely populated regions, and pulp industries in forest regions. Alcohols for transportation and stand-alone power production are preferably produced in less densely populated regions with excess biomass. A high intensity in biomass production would reduce biomass transportation demands. There are uncertainties regarding the future demand for stem wood for building and industrial purposes, the amount of arable land available for energy crop production and future yields. These factors will influence Swedish biomass potential and earlier estimates of the potential vary from 15 to 125 TWh/yr.
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