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Sökning: WFRF:(Gustavsson P) > Karlstads universitet

  • Resultat 1-8 av 8
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1.
  • Balk, Lennart, et al. (författare)
  • Widespread episodic thiamine deficiency in Northern Hemisphere wildlife
  • 2016
  • Ingår i: Scientific Reports. - : Nature Publishing Group. - 2045-2322. ; 6
  • Tidskriftsartikel (refereegranskat)abstract
    • Many wildlife populations are declining at rates higher than can be explained by known threats to biodiversity. Recently, thiamine (vitamin B-1) deficiency has emerged as a possible contributing cause. Here, thiamine status was systematically investigated in three animal classes: bivalves, ray-finned fishes, and birds. Thiamine diphosphate is required as a cofactor in at least five life-sustaining enzymes that are required for basic cellular metabolism. Analysis of different phosphorylated forms of thiamine, as well as of activities and amount of holoenzyme and apoenzyme forms of thiaminedependent enzymes, revealed episodically occurring thiamine deficiency in all three animal classes. These biochemical effects were also linked to secondary effects on growth, condition, liver size, blood chemistry and composition, histopathology, swimming behaviour and endurance, parasite infestation, and reproduction. It is unlikely that the thiamine deficiency is caused by impaired phosphorylation within the cells. Rather, the results point towards insufficient amounts of thiamine in the food. By investigating a large geographic area, by extending the focus from lethal to sublethal thiamine deficiency, and by linking biochemical alterations to secondary effects, we demonstrate that the problem of thiamine deficiency is considerably more widespread and severe than previously reported.
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  • Friman, Margareta, et al. (författare)
  • Services and issues relating to the work environment
  • 1996
  • Ingår i: B. Edvardsson & S. Modell (Eds.), Service managment. Interdiciplinary percepectives. (pp. 151-180). - Stockholm : Nerenius & Santérus.
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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  • Wittchen, H U, et al. (författare)
  • The size and burden of mental disorders and other disorders of the brain in Europe 2010.
  • 2011
  • Ingår i: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. - : Elsevier BV. - 1873-7862 .- 0924-977X. ; 21:9, s. 655-79
  • Tidskriftsartikel (refereegranskat)abstract
    • To provide 12-month prevalence and disability burden estimates of a broad range of mental and neurological disorders in the European Union (EU) and to compare these findings to previous estimates. Referring to our previous 2005 review, improved up-to-date data for the enlarged EU on a broader range of disorders than previously covered are needed for basic, clinical and public health research and policy decisions and to inform about the estimated number of persons affected in the EU.
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  • Resultat 1-8 av 8
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Karlstads universitet  (8)Ta bort avgränsningen
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