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Sökning: WFRF:(Haik S)

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  • Lauwers, E., et al. (författare)
  • Potential human transmission of amyloid beta pathology: surveillance and risks
  • 2020
  • Ingår i: Lancet Neurology. - 1474-4422. ; 19:10, s. 872-878
  • Tidskriftsartikel (refereegranskat)abstract
    • Studies in experimental animals show transmissibility of amyloidogenic proteins associated with prion diseases, Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases. Although these data raise potential concerns for public health, convincing evidence for human iatrogenic transmission only exists for prions and amyloid beta after systemic injections of contaminated growth hormone extracts or dura mater grafts derived from cadavers. Even though these procedures are now obsolete, some reports raise the possibility of iatrogenic transmission of amyloid beta through putatively contaminated neurosurgical equipment. Iatrogenic transmission of amyloid beta might lead to amyloid deposition in the brain parenchyma and blood vessel walls, potentially resulting in cerebral amyloid angiopathy after several decades. Cerebral amyloid angiopathy can cause life-threatening brain haemorrhages; yet, there is no proof that the transmission of amyloid can also lead to Alzheimer's dementia. Large, long-term epidemiological studies and sensitive, cost-efficient tools to detect amyloid are needed to better understand any potential routes of amyloid beta transmission and to clarify whether other similar proteopathic seeds, such as tau or alpha-synuclein, can also be transferred iatrogenically.
  • Röder, Marko, et al. (författare)
  • Coulomb dissociation of N 20,21
  • 2016
  • Ingår i: Physical Review C - Nuclear Physics. - : American Physical Society. - 0556-2813. ; 93:6
  • Tidskriftsartikel (refereegranskat)abstract
    • Neutron-rich light nuclei and their reactions play an important role in the creation of chemical elements. Here, data from a Coulomb dissociation experiment on N20,21 are reported. Relativistic N20,21 ions impinged on a lead target and the Coulomb dissociation cross section was determined in a kinematically complete experiment. Using the detailed balance theorem, the N19(n,γ)N20 and N20(n,γ)N21 excitation functions and thermonuclear reaction rates have been determined. The N19(n,γ)N20 rate is up to a factor of 5 higher at T<1GK with respect to previous theoretical calculations, leading to a 10% decrease in the predicted fluorine abundance.
  • Ozolins, Oskars, et al. (författare)
  • 140 Gbaud On-Off Keying Links in C-Band for Short-Reach Optical Interconnects
  • 2018
  • Ingår i: European Conference on Optical Communication, ECOC. - : Institute of Electrical and Electronics Engineers Inc.. - 9781538648629
  • Konferensbidrag (refereegranskat)abstract
    • We demonstrate 140 Gbaud intensity modulated direct detection dispersion-uncompensated links with Mach Zehnder modulator and distributed feedback travelling-wave electro-absorption modulator over 5500 and 960 meters of standard single mode fibre, respectively, enabled by compact packaged ultra-high speed InP-based 2:1-Selector.
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  • Resultat 1-8 av 8

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