Search: WFRF:(Hakeberg Magnus 1954 )
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> Bratel John 1953 >
The effect of Longo...
The effect of LongoVital on recurrent aphthous stomatitis in a controlled clinical trial.
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- Bratel, John, 1953 (author)
- Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology
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- Hakeberg, Magnus, 1954 (author)
- Jönköping University,Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology,HHJ, Avdelningen för naturvetenskap och biomedicin,HHJ. Centrum för oral hälsa
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- Jontell, Mats, 1951 (author)
- Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology
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(creator_code:org_t)
- 2005
- 2005
- English.
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In: Oral health & preventive dentistry. - 1602-1622. ; 3:1, s. 3-8
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Abstract
Subject headings
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- PURPOSE: The aim of this study was to evaluate the effect of daily intake of LongoVital (LV) (herbal vitamin tablets) in the prevention of RAS. MATERIALS AND METHODS: A group of 78 consecutively referred patients was enrolled to a three-months pretreatment period. Fifty subjects were then randomly allocated to an LV-group (n = 25) or a placebo group (N = 25). A double blind, stratified-randomised clinical case-control study was performed during six months. Number and size of the ulcers were registered by the patients using a standardized chart. The degree of discomfort was recorded on a 100 mm horizontal visual analogue scale (VAS-scale). RESULTS: The three-months pretreatment period revealed that the most dominant symptoms were pain (78%) followed by burning sensation (18%). No significant differences between the two groups were found during this period when a comparison was made at the end of the study. After the intervention period the number of aphthous ulcers/month decreased significantly in the LV-group (p = 0.02). The number of days in pain/month were also reduced (p < 0.001). If a 50% reduction of number of aphthous ulcers and days in pain were considered as clinically relevant, no statistical significant differences were found between the groups. CONCLUSION: Thus, no strong evidence was found that justified a recommendation of LV as a general drug for treatment of RAS.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Keyword
- Adult
- Aged
- Double-Blind Method
- Drug Combinations
- Female
- Humans
- Male
- Middle Aged
- Phytotherapy
- Plant Components
- Plant Preparations
- therapeutic use
- Plants
- Medicinal
- Recurrence
- prevention & control
- Statistics
- Nonparametric
- Stomatitis
- Aphthous
- prevention & control
- Tablets
- Vitamins
- therapeutic use
- Adult
Publication and Content Type
- ref (subject category)
- art (subject category)
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