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Träfflista för sökning "WFRF:(Hansson Niklas 1977 ) "

Sökning: WFRF:(Hansson Niklas 1977 )

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  • Egecioglu, Emil, 1977, et al. (författare)
  • Central NMU signaling in body weight and energy balance regulation: evidence from NMUR2 deletion and chronic central NMU treatment in mice.
  • 2009
  • Ingår i: American journal of physiology. Endocrinology and metabolism. - 1522-1555 .- 0193-1849. ; 297:3, s. E708-16
  • Tidskriftsartikel (refereegranskat)abstract
    • To investigate the role of the central neuromedin U (NMU) signaling system in body weight and energy balance regulation, we examined the effects of long-term intracerebroventricular (icv) infusion of NMU in C57Bl/6 mice and in mice lacking the gene encoding NMU receptor 2. In diet-induced obese male and female C57BL/6 mice, icv infusion of NMU (8 microg x day(-1) x mouse(-1)) for 7 days decreased body weight and total energy intake compared with vehicle treatment. However, these parameters were unaffected by NMU treatment in lean male and female C57BL/6 mice fed a standard diet. In addition, female (but not male) NMUR2-null mice had increased body weight and body fat mass when fed a high-fat diet but lacked a clear body weight phenotype when fed a standard diet compared with wild-type littermates. Furthermore, female (but not male) NMUR2-null mice fed a high-fat diet were protected from central NMU-induced body weight loss compared with littermate wild-type mice. Thus, we provide the first evidence that long-term central NMU treatment reduces body weight, food intake, and adiposity and that central NMUR2 signaling is required for these effects in female but not male mice.
  • Egels-Zandén, Niklas, 1978, et al. (författare)
  • Supply chain transparency as a consumer or corporate tool: The case of Nudie Jeans Co
  • 2016
  • Ingår i: Journal of Consumer Policy. - : Springer. - 0168-7034 .- 1573-0700. ; 39:4
  • Tidskriftsartikel (refereegranskat)abstract
    • Outsourcing has led both to the embedding of questionable sustainability practices in opaque supply chains and to anti-sweatshop challenges demanding more transparent supply chains. Previous research has argued that supply chain transparency can be both a consumer tool empowering consumers to pressure disclosing firms to improve sustainability conditions, and a corporate tool for increasing revenues. Based on a study of the transparency project of Swedish company Nudie Jeans, we demonstrate that consumers do not leverage transparency but that transparency improves consumer willingness to buy. In doing this, we contribute to the literature in two important ways. First, we provide one of the first, if not the first, studies of whether consumers in practice leverage increased supply chain transparency, challenging the previous research claim that supply chain transparency is a useful consumer tool. Second, we move beyond studies of purchasing intentions and willingness to buy in experimental settings and confirm that supply chain transparency is a useful corporate tool in practice. We conclude by discussing the policy implications of companies being able to use transparency to increase sales without subjecting themselves to increased consumer pressure.
  • Martínez-Morillo, E., et al. (författare)
  • Assessment of peptide chemical modifications on the development of an accurate and precise multiplex selected reaction monitoring assay for Apolipoprotein e isoforms
  • 2014
  • Ingår i: Journal of Proteome Research. - : The American Chemical Society (ACS). - 1535-3893. ; 13:2, s. 1077-1087
  • Tidskriftsartikel (refereegranskat)abstract
    • Apolipoprotein E (ApoE) is a polymorphic protein that plays a major role in lipid metabolism in the central nervous system and periphery. It has three common allelic isoforms, ApoE2, ApoE3, and ApoE4, that differ in only one or two amino acids. ApoE isoforms have been associated with the occurrence and progression of several pathological conditions, such as coronary atherosclerosis and Alzheimer's disease. The aim of this study was to develop a mass spectrometry (MS)-based assay for absolute quantification of ApoE isoforms in cerebrospinal fluid and plasma samples using isotope-labeled peptides. The assay included five tryptic peptides: CLAVYQAGAR (ApoE2), LGADMEDVCGR (ApoE2 and 3), LAVYQAGAR (ApoE3 and 4), LGADMEDVR (ApoE4), and LGPLVEQGR (total ApoE). Both cerebrospinal fluid and plasma samples were assayed to validate the method. The digestion yield and the extension of chemical modifications in selected amino acid residues (methionine oxidation, glutamine deamidation, and cyclization of N-terminus carbamidomethylcysteine) were also studied. The ApoE phenotype was successfully assigned to all samples analyzed in a blinded manner. The method showed good linearity (R2 > 0.99) and reproducibility (within laboratory imprecision <13%). The comparison of the MS-based assay with an ELISA for total ApoE concentration showed a moderate correlation (R2 = 0.59). This MS-based assay can serve as an important tool in clinical studies aiming to elucidate the association between ApoE genotype, total ApoE, and ApoE isoform concentrations in various disorders related to ApoE polymorphisms. © 2014 American Chemical Society.
  • Brembeck, Helene, 1952, et al. (författare)
  • Biking consumers: bags, bikes and sustainability
  • 2013
  • Ingår i: International Society for Ethnology and Folklore, SIEF, Conference, Tartu 30 June – 4 July 2013.
  • Konferensbidrag (refereegranskat)abstract
    • Things are not always consumed at the same place where they were obtained and this generates a mobility of moving things that the consumer is responsible for, i.e. a mundane consumer logistic conducted by customers while moving things from stores to places where the things are used. Means of transport and carrying for "getting this work done", for example bicycles, are not essentially enabling or disabling: for the strong, healthy and able-bodied, cycling equals healthy pleasure and leisure but the slightly "over-carrying" person moving recent purchases might perceive the physical environment more in terms of risk than aesthetic pleasure. The aim of the paper is to discuss discrepancies between cycling as a represented sustainable form of urban transportation as promoted in policy programs in Sweden and cyclists' experiences of bringing goods back from the store. Over the last ten or more years bicycling has reached a top place on both the academic and policy agenda in search for ways to increase use of bicycles as they are seen as healthy and sustainable means of urban transportation. When doing everyday consumer errands like grocery shopping, any aesthetic pleasure, effects on health or the environment derived from cycling must be related to experiences of discomfort, physical effort and safety measures. In this paper we confront sustainability transport policy directed towards urban dwellers with an ethnographic analysis of biking consumers. We combine data obtained through in-depth interviews and "go-along observations" with families with small children and elderly people.
  • Brembeck, Helene, 1952, et al. (författare)
  • Life phases, mobility and consumption. An ethnography of shopping routes
  • 2015
  • Bok (övrigt vetenskapligt)abstract
    • The very routines of our daily life are to a great extent the expression of our vulnerability and dependence on incredibly wide and complex networks and socio-technical systems. Following people’s routes in the city, makes visible the differentially distributed capacities and potentials for mobility. In today’s consumer society, shopping is the kind of mundane and routine mobility that we all engage in. Yet having a first child or growing old radically changes people’s logistical habits as consumers, what the authors of this book call consumer logistics; moving from home to the store and back home again with recent purchases. Depending on the ages and number of children in the family and the condition of one’s body (physical health and strength), going shopping requires quite different settings and gear. Exploring consumer mobility through the lens of life phase and age will deepen the understanding of hitherto under-researched aspects of the ageing process, and of mobility, knowledge that is of vital importance for societies striving for sustainable mobility and sustainable cities.
  • Brembeck, Helene, 1952, et al. (författare)
  • Shopping Routes: life phase, mobility and consumption
  • 2014
  • Ingår i: Midterm Conference of the Research Network of Sociology of Consumption (European Sociological Association) ESA, Porto Sept 3-6, 2014 (konferensbidrag).
  • Konferensbidrag (refereegranskat)
  • Fuentes, Christian, 1978, et al. (författare)
  • Green shopping apps as market devices: materialities, competences and moralities
  • 2014
  • Ingår i: www.nrwa.se.
  • Konferensbidrag (övrigt vetenskapligt)abstract
    • In this paper we examine ethical shopping apps as market devices. Focusing on three “ethical” apps” available on the Swedish market, we examine the prescriptions built into these devices. The preliminary analysis carried out shows that the ethical apps examined all work to encourage and allow certain ethical/responsible consumer practices and subjectivities. They are designed to extend the consumption capabilities of the consumers that use them and shape their ways of seeing and thinking about ethical consumption.
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