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LifeTime and improving European healthcare through cell-based interceptive medicine

Rajewsky, N. (author)
Almouzni, G. (author)
Gorski, S. A. (author)
show more...
Aerts, S. (author)
Amit, I. (author)
Bertero, M. G. (author)
Bock, C. (author)
Bredenoord, A. L. (author)
Cavalli, G. (author)
Chiocca, S. (author)
Clevers, H. (author)
De Strooper, B. (author)
Eggert, A. (author)
Ellenberg, J. (author)
Fernández, X. M. (author)
Figlerowicz, M. (author)
Gasser, S. M. (author)
Hubner, N. (author)
Kjems, J. (author)
Knoblich, J. A. (author)
Krabbe, G. (author)
Lichter, P. (author)
Linnarsson, S. (author)
Karolinska Institutet
Marine, J. -C (author)
Marioni, J. (author)
Marti-Renom, M. A. (author)
Netea, M. G. (author)
Nickel, D. (author)
Nollmann, M. (author)
Novak, H. R. (author)
Parkinson, H. (author)
Piccolo, S. (author)
Pinheiro, I. (author)
Pombo, A. (author)
Popp, C. (author)
Reik, W. (author)
Roman-Roman, S. (author)
Rosenstiel, P. (author)
Schultze, J. L. (author)
Stegle, O. (author)
Tanay, A. (author)
Testa, G. (author)
Thanos, D. (author)
Theis, F. J. (author)
Torres-Padilla, M. -E (author)
Valencia, A. (author)
Vallot, C. (author)
van Oudenaarden, A. (author)
Vidal, M. (author)
Voet, T. (author)
Alberi, L. (author)
Alexander, S. (author)
Alexandrov, T. (author)
Arenas, E. (author)
Bagni, C. (author)
Balderas, R. (author)
Bandelli, A. (author)
Becher, B. (author)
Becker, M. (author)
Beerenwinkel, N. (author)
Benkirame, M. (author)
Beyer, M. (author)
Bickmore, W. (author)
Biessen, E. E. A. L. (author)
Blomberg, N. (author)
Blumcke, I. (author)
Bodenmiller, B. (author)
Borroni, B. (author)
Boumpas, D. T. (author)
Bourgeron, T. (author)
Bowers, S. (author)
Braeken, D. (author)
Brooksbank, C. (author)
Brose, N. (author)
Bruining, H. (author)
Bury, J. (author)
Caporale, N. (author)
Cattoretti, G. (author)
Chabane, N. (author)
Chneiweiss, H. (author)
Cook, S. A. (author)
Curatolo, P. (author)
de Jonge, M. I. (author)
Deplancke, B. (author)
de Witte, P. (author)
Dimmeler, S. (author)
Draganski, B. (author)
Drews, A. -D (author)
Dumbrava, C. (author)
Engelhardt, S. (author)
Gasser, T. (author)
Giamarellos-Bourboulis, E. J. (author)
Graff, C. (author)
Grün, D. (author)
Gut, I. (author)
Hansson, O. (author)
Henshall, D. C. (author)
Herland, Anna (author)
KTH,Mikro- och nanosystemteknik
Heutink, P. (author)
Heymans, S. R. B. (author)
Heyn, H. (author)
Huch, M. (author)
Huitinga, I. (author)
Jackowiak, P. (author)
Jongsma, K. R. (author)
Journot, L. (author)
Junker, J. P. (author)
Katz, S. (author)
Kehren, J. (author)
Kempa, S. (author)
Kirchhof, P. (author)
Klein, C. (author)
Koralewska, N. (author)
Korbel, J. O. (author)
Kühnemund, M. (author)
Lamond, A. I. (author)
Lauwers, E. (author)
Le Ber, I. (author)
Leinonen, V. (author)
Tobon, A. L. (author)
Lundberg, E. (author)
Lunkes, A. (author)
Maatz, H. (author)
Mann, M. (author)
Marelli, L. (author)
Matser, V. (author)
Matthews, P. M. (author)
Mechta-Grigoriou, F. (author)
Menon, R. (author)
Nielsen, A. F. (author)
Pagani, M. (author)
Pasterkamp, R. J. (author)
Pitkanen, A. (author)
Popescu, V. (author)
Pottier, C. (author)
Puisieux, A. (author)
Rademakers, R. (author)
Reiling, D. (author)
Reiner, O. (author)
Remondini, D. (author)
Ritchie, C. (author)
Rohrer, J. D. (author)
Saliba, A. -E (author)
Sanchez-Valle, R. (author)
Santosuosso, A. (author)
Sauter, A. (author)
Scheltema, R. A. (author)
Scheltens, P. (author)
Schiller, H. B. (author)
Schneider, A. (author)
Seibler, P. (author)
Sheehan-Rooney, K. (author)
Shields, D. (author)
Sleegers, K. (author)
Smit, G. (author)
Smith, K. G. C. (author)
Smolders, I. (author)
Synofzik, M. (author)
Tam, W. L. (author)
Teichmann, S. (author)
Thom, M. (author)
Turco, M. Y. (author)
van Beusekom, H. M. M. (author)
Vandenberghe, R. (author)
den Hoecke, S. V. (author)
Van de Poel, I. (author)
der Ven, A. (author)
van der Zee, J. (author)
van Lunzen, J. (author)
van Minnebruggen, G. (author)
Van Paesschen, W. (author)
van Swieten, J. (author)
van Vught, R. (author)
Verhage, M. (author)
Verstreken, P. (author)
Villa, C. E. (author)
Vogel, J. (author)
von Kalle, C. (author)
Walter, J. (author)
Weckhuysen, S. (author)
Weichert, W. (author)
Wood, L. (author)
Ziegler, A. -G (author)
Zipp, F. (author)
Community, LifeTime (author)
show less...
 (creator_code:org_t)
2020-09-07
2020
English.
In: Nature. - : Springer Nature. - 0028-0836 .- 1476-4687. ; 587:7834, s. 377-386
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • LifeTime aims to track, understand and target human cells during the onset and progression of complex diseases and their response to therapy at single-cell resolution. This mission will be implemented through the development and integration of single-cell multi-omics and imaging, artificial intelligence and patient-derived experimental disease models during progression from health to disease. Analysis of such large molecular and clinical datasets will discover molecular mechanisms, create predictive computational models of disease progression, and reveal new drug targets and therapies. Timely detection and interception of disease embedded in an ethical and patient-centered vision will be achieved through interactions across academia, hospitals, patient-associations, health data management systems and industry. Applying this strategy to key medical challenges in cancer, neurological, infectious, chronic inflammatory and cardiovascular diseases at the single-cell level will usher in cell-based interceptive medicine in Europe over the next decade.

Subject headings

NATURVETENSKAP  -- Biologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences (hsv//eng)
NATURVETENSKAP  -- Biologi -- Bioinformatik och systembiologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Bioinformatics and Systems Biology (hsv//eng)

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art (subject category)

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Rajewsky, N.
Almouzni, G.
Gorski, S. A.
Aerts, S.
Amit, I.
Bertero, M. G.
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Gasser, S. M.
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Kehren, J.
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Kirchhof, P.
Klein, C.
Koralewska, N.
Korbel, J. O.
Kühnemund, M.
Lamond, A. I.
Lauwers, E.
Le Ber, I.
Leinonen, V.
Tobon, A. L.
Lundberg, E.
Lunkes, A.
Maatz, H.
Mann, M.
Marelli, L.
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Mechta-Grigoriou ...
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Popescu, V.
Pottier, C.
Puisieux, A.
Rademakers, R.
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Reiner, O.
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Ritchie, C.
Rohrer, J. D.
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Santosuosso, A.
Sauter, A.
Scheltema, R. A.
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About the subject
NATURAL SCIENCES
NATURAL SCIENCES
and Biological Scien ...
NATURAL SCIENCES
NATURAL SCIENCES
and Biological Scien ...
and Bioinformatics a ...
Articles in the publication
Nature
By the university
Royal Institute of Technology
Karolinska Institutet

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