| 1. |
- Eurell, John-Christian, Teol DR, 1987-
(författare)
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Peter's legacy in early christianity : the appropriation and use of Peter's authority in the first three centuries
- 2021
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This study combines traditional historical-critical methods with the sociological theories of Max Weber and Pierre Bourdieu in order to discuss how Peter’s authority is portrayed and used to create legitimacy in Christian texts from the first three centuries. The New Testament texts that mention Peter are discussed together with other early Christian writings that in one way or another relate to Peter as an authoritative figure. Peter emerges as a central figure in the diverse early Christian movement and is used to a high degree to discuss theological legitimacy. The main divide is between those who argue that legitimate theology should have a conservative point of departure based on traditional material handed down from the earthly Jesus and an apostolic succession based on interpersonal relations and those who argue in favour of a more progressive point of departure which places more emphasis on contemporary charismatic experiences. Both these perspectives are used by groups of various theological persuasion in order to argue their own position. Peter is sometimes used to legitimise a theological position with reference to Peter’s relationship to the earthly Jesus and sometimes to discredit traditions concerning the earthly Jesus by pointing out that Peter did not understand his true message. Peter is used as both positive and negative example for both these ways of creating legitimacy.
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| 2. |
- Hedrén, Andreas, 1967-
(författare)
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With Lives on the Line : How Users Respond to a Highly Mandated Information System Implementation - A Longitudinal Study
- 2021
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Some people are forced to use a specific technology in their work. Should they resist, people die. This thesis examines the implementation of a Patient Data Management System for the critical care departments at two Swedish hospitals. The degree of mandate to use a technology varies along a spectrum anchored between none and absolute. This thesis focuses on the context of absolute mandated use, an area unexplored by Information System (IS) research.Use of technology is a well-established indicator of the success of IS implementation. Nonetheless, when IS is required, use is not a suitable indicator of success. Instead, affectual responses, such as attitudes regarding use and satisfaction, are appropriate indicators of success. This thesis recognizes the process nature of implementation and develops a longitudinal four-stage research model to predict the attitude of individual end-users during the implementation of an IS. The model’s first part considers the stage where users do not yet have first-hand experiences of using the system. The following parts of the model relate to different stages of the implementation process and the final part addresses the stage of the implementation process where IS use has become routine.To test the research model, this research used data collected through field surveys. Non-parametric covariance based (CB) structural equation modelling (SEM) analyses revealed that the users’ perceptions of IS use changed over time and kept changing for months. The results further indicate that both the set of variables and the degree of their influence on a users’ perceptions vary during the implementation process. Furthermore, the users’ trust in the adequate functioning of the system is a persistent predictor of the users’ attitudes. In contrast to many reported findings in the literature, users’ resistance to change is not an influential factor at any stage of the implementation process. Finally, the influence of communication through the organisational channels only affects the users’ perceptions before they have first-hand experience with the IS. This research contributes to the IS literature by uncovering mechanisms of the increasingly ubiquitous although un-investigated phenomenon of highly mandated use. This research reports on causal drivers of users’ attitude towards highly mandated use and how the influence of these drivers develops throughout an implementation process.
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| 3. |
- Lundgren, Camilla A. K., 1982-
(författare)
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Structural and Functional Studies of Membrane Proteins : From Characterisation of a Fatty Acyl-CoA Synthetase to the Discovery of Superoxide Oxidase
- 2019
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis is divided into three parts; the first part describes a method for efficient screening of membrane proteins for crystallography. By utilising the properties of a folding reporter GFP it is possible to quickly and accurately screen the stability of a protein in a range of conditions without full purification. This allows rapid assessment of the suitability of a protein for crystallography and a parallel optimisation of purification conditions for subsequent large-scale protein production.The second part describes the discovery of a membrane bound superoxide oxidase (SOO), a novel scavenger of membrane proximal superoxide. SOO is a kinetically perfect enzyme, reacting at rates close to the diffusion limit in a similar fashion to other superoxide scavengers, such as superoxide dismutase. We propose that SOO rescues electrons “lost” to superoxide and recycles them back into the respiratory chain, releasing oxygen. At the same time SOO contributes to the proton motive force by uptake of protons from the cytoplasmic side of the membrane.The third part concerns the fatty acyl-CoA synthetase FadD13 from Mycobacterium tuberculosis (M. tuberculosis). It represents a critical node point in M. tuberculosis lipid metabolism and has been suggested to be a vital component of M. tuberculosis survival in host cell macrophages. FadD13 harbours a hydrophobic cavity that is unable to house the very-long-chain substrates the enzyme has preference for. We propose that FadD13 is a peripheral membrane protein, utilising the membrane to house the very-long-chain fatty acid substrates during the activation reaction.
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| 4. |
- Moe, Agnes, 1990-
(författare)
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Role of respiratory supercomplexes : Electronic connection between complexes III and IV
- 2023
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- In the final step of cellular respiration, electrons are transferred through the respiratory chain to reduce molecular oxygen to water. The energy released in this chain is used to maintain a proton electrochemical gradient across the cell membrane, which is used, for example, by the ATP synthase to produce ATP. The enzyme complexes of the respiratory chain are known to organize in supramolecular assemblies, so-called respiratory supercomplexes.In this work we investigated the functional significance of respiratory supercomplexes consisting of complexes III and IV in mitochondria. By combining structural and kinetic studies we showed that at the commonly assumed "physiological" ionic strength of 150 mM monovalent salt, the water-soluble cyt. c associates with the negatively charged surface of III2-IV1-2 supercomplexes in the yeast species Saccharomyces cerevisiae and Schizosaccharomyces pombe. The data showed that one cyt. c diffuses in 2D, between complexes III and IV, indicating a kinetic advantage of forming supercomplexes. These studies also showed different relative orientation of the individual complexes in the supercomplexes from the two yeast species, indicating that 2D diffusion is a general mechanism, not limited to a specific relative orientation of complexes III and IV. More recent data in the literature indicate that a more realistic mimic of intracellular conditions is a monovalent salt concentration of 20 mM. We showed that under these conditions two cyt. c molecules bind simultaneously to the supercomplex. This result further supports a kinetic advantage of forming supercomplexes.We also determined the cryo-EM structure of the obligate III2-IV2 supercomplex from the Gram-positive bacterium Corynebacterium glutamicum. The structure revealed an electronic connection between complexes III and IV by a di-heme cyt. cc subunit. The structure also showed that complexes III and IV are structurally intertwined and strongly connected with unique features conserved in the phylum actinobacteria.
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| 5. |
- O'Reilly, Bim, 1985-
(författare)
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Baptism and Death : A Study of Mark and Romans
- 2017
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Does baptism in some way associate an initiate with the death and resurrection of Christ? From the fourth century until the present, this understanding has had a central place in defining the meaning of baptism. In the NT, baptism and death are associated in two ways. In Rom 6:3–4, Paul argues that being baptised into Christ entails being baptised into Christ’s death. In Mark 10:38–39, Jesus uses the notion of being baptised with a baptism as a metaphor for his suffering and death. Although these ways of associating baptism and death are different, scholars have offered varying explanations for the ideas expressed in Mark and Romans and for their possible relationship to each other. The purpose of the thesis is to examine the presentation of, and the relationship between, baptism and death in Mark and Romans, and to compare the associations of baptism and death in the two texts. As a theoretical point of departure, an overarching holistic and inner-textual approach is adopted. Additional approaches are used for the respective texts: a narrative approach for Mark and an argumentative approach for Romans. In each of the analyses of Mark and Romans, the macrostructures of the texts form a framework for interpreting key passages for understanding the relationship between baptism and death. The results of these analyses are then brought together in a comparative analysis, where similarities and differences between Mark and Romans are weighed.The analysis shows that the ways of associating of baptism and death in Mark 10:38–39 and Rom 6:3–4 are different. Nonetheless, the associations are part of similar contexts, where baptism seems to have a function of helping to establish, or confirm, an identity based on, and modelled by, the crucified Christ, and that call for action in some way. A point of contact should therefore not be sought on the basis of the associations of baptism and death in Mark 10:38–39 and Rom 6:3–4, but in the broad ways the texts reflect on the significance of Christ’s death for those who want to follow Jesus or to be “in Christ”.
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| 6. |
- Pixton, Tonya S., 1974-
(författare)
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Expecting Happy Women, Not Detecting the Angry Ones : Detection and Perceived Intensity of Facial Anger, Happiness, and Emotionality
- 2011
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Faces provide cues for judgments regarding the emotional state of individuals. Using signal-detection methodology and a standardized stimulus set, the overall aim of the present dissertation was to investigate the detection of emotional facial expressions (i.e., angry and happy faces) with neutral expressions as the nontarget stimuli. Study I showed a happy-superiority effect and a bias towards reporting happiness in female faces. As work progressed, questions arose regarding whether the emotional stimuli were equal with regard to perceived strength of emotion, and whether the neutral faces were perceived as neutral. To further investigate the effect of stimulus quality on the obtained findings, Study II was designed such that the facial stimuli were rated on scales of happy-sad, angry-friendly, and emotionality. Results showed that ‘neutral’ facial expressions were not rated as neutral, and that there was a greater perceived distance between happy and neutral faces than between angry and neutral faces. These results were used to adjust the detectability measures to compensate for the varying distances of the angry and happy stimuli from the neutral stimuli in the emotional space. The happy-superiority effect was weakened, while an angry-female disadvantage remained. However, as these results were based upon different participant groups for detection and emotional rating, Study III was designed to investigate whether the results from Studies I and II could be replicated in a design where the same participants performed both tasks. Again, the results showed the non-neutrality of ‘neutral’ expressions and that happiness was more easily detected than anger, as shown in general emotion as well as specific emotion detection. Taken together, the overall results of the present dissertation demonstrate a happy-superiority effect that was greater for female than male faces, that angry-female faces were the most difficult to detect, and a bias to report female faces as happy.
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| 7. |
- Willander, Erika, 1978-
(författare)
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What Counts as Religion in Sociology? : The Problem of Religiosity in Sociological Methodology
- 2014
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis aims to contribute to the ongoing critical discussion within the sociology of religion by focusing on the seldom considered perspective of methodology. As such, it consists of a theoretical part that problematizes the ways in which religion has been analyzed, and an empirical part that develops how religiosity can be approached in sociological studies. The thesis seeks, in other words, to contribute to how sociologists analyze religion, and addresses a research problem that has gained new relevance in the aftermath of criticism of the secularization paradigm. In the theoretical part, the assumptions underlying the ways in which religion is studied are revisited, as is the impact that these have had as faras the empirical study of religion is concerned in one of the countries often assumed to be secularized – i.e. Sweden. The empirical part of the thesis is comprised of three studies based on the latest European Value Survey, qualitative interviews and the Blogosphere on religion-related content (n=220000 blog posts). The results from these studies are used to reconsider the religiousmainstream, the “package”-like assumptions often made about affiliation, belief and practice, as well as the fact that the study of religiosity tends to be relegated to the periphery of the imagination of sociologists of religion. The thesis proposes that if we want to study religion in a lay people sensitive way we cannot continue to overlook their understandings of the sacred, the ways in which they regard their own religiosity, and the fact that their affiliation,belief and practice do not necessarily fit the expectations of established ways of analyzing religion.
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