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Sökning: WFRF:(Jesson J)

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  • Williams, David J., et al. (författare)
  • Comparability : Manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015
  • 2016
  • Ingår i: Regenerative Medicine. - : Future Medicine Ltd. - 1746-0751 .- 1746-076X. ; 11:5, s. 483-492
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper summarizes the proceedings of a workshop held at Trinity Hall, Cambridge to discuss comparability and includes additional information and references to related information added subsequently to the workshop. Comparability is the need to demonstrate equivalence of product after a process change; a recent publication states that this 'may be difficult for cell-based medicinal products'. Therefore a well-managed change process is required which needs access to good science and regulatory advice and developers are encouraged to seek help early. The workshop shared current thinking and best practice and allowed the definition of key research questions. The intent of this report is to summarize the key issues and the consensus reached on each of these by the expert delegates.
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  • Zheng, C. X., et al. (författare)
  • Mapping the surface phase diagram of GaAs(001) using droplet epitaxy
  • 2019
  • Ingår i: Physical Review Materials. - 2475-9953. ; 3:12
  • Tidskriftsartikel (refereegranskat)abstract
    • We combine droplet epitaxy with low-energy electron microscopy imaging techniques to map the surface phase diagram of GaAs(001). The phase patterns produced in droplet epitaxy are interpreted using a simple model which links the spatial coordinates of phase boundaries to the free energy. It is thereby possible to gain important information on surface phase stability, based on the observed sequential order of the phases away from the droplet edge. This can be used to augment existing T=0K phase diagrams generated by density-functional theory calculations. We establish the existence of a (3×6) phase, and confirm that the controversial (6×6) phase is thermodynamically stable over a narrow range of chemical potential.
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