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Sökning: WFRF:(Jiang Y.) > Jönköping University

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1.
  • Wightman, D. P., et al. (författare)
  • A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease
  • 2021
  • Ingår i: Nature Genetics. - : Springer Nature. - 1061-4036 .- 1546-1718. ; 53:9, s. 1276-1282
  • Tidskriftsartikel (refereegranskat)abstract
    • Late-onset Alzheimer’s disease is a prevalent age-related polygenic disease that accounts for 50–70% of dementia cases. Currently, only a fraction of the genetic variants underlying Alzheimer’s disease have been identified. Here we show that increased sample sizes allowed identification of seven previously unidentified genetic loci contributing to Alzheimer’s disease. This study highlights microglia, immune cells and protein catabolism as relevant to late-onset Alzheimer’s disease, while identifying and prioritizing previously unidentified genes of potential interest. We anticipate that these results can be included in larger meta-analyses of Alzheimer’s disease to identify further genetic variants that contribute to Alzheimer’s pathology.
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2.
  • Palesi, Maurizio, et al. (författare)
  • A Novel Mechanism to Guarantee In-Order Packet Delivery with Adaptive Routing Algorithms in Networks on Chip
  • 2010
  • Ingår i: 13th Euromicro Conference On Digital System Design Architectures, Methods and Tools.
  • Konferensbidrag (refereegranskat)abstract
    • Although adaptive routing algorithms promise higher communication performance, as compared to deterministic routing algorithms, they suffer from the out-of-order packet delivery problem. In the context of Network on Chip, the area and computational overhead of ordering packets at the destination is high and may reverse any gain achieved through the use of adaptivity of the routing algorithm. In this paper, we describe a novel scheme for ensuring in-order packet delivery while retaining the performance advantages of adaptive routing. The hardware architecture of a router that supports the proposed scheme is described. Although the basic idea in our proposal is topology independent we evaluate and compare the performance of our scheme with both deterministic as well as adaptive routing algorithms for 2D mesh NoC. As compared to the XY routing algorithm, our technique significantly reduces the packet delay and improves the saturation point. The impact on router area and power dissipation is also discussed. Although the power consumption of routers increase, the energy consumption per flit increases less than 2% on average, since the higher performance allows for draining more traffic during a certain time window.
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