| 1. |
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| 2. |
- Johansson, Ted, et al.
(author)
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Influence of SOI-generated stress on BiCMOS performance
- 2006
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In: Solid-State Electronics. - : Elsevier BV. - 0038-1101 .- 1879-2405. ; 50:6, s. 935-942
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Journal article (peer-reviewed)abstract
- Two BiCMOS processes were adapted for SOI and the performance of the bipolar devices was studied. Differences in electrical parameters were observed, in particular the current gain, which processing or doping profiles could not explain, but correlated with observed stress in transistors. Simulation of the process flow with stress included revealed that stress was generated to a higher degree in the SOI wafers in the presence of deep trench isolation (DTI). Theoretical estimations and electrical simulations with and without stress yielded results consistent with observed data. Thus, we conclude that the observed differences are caused by process-induced in-plane biaxial stress.
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| 3. |
- Alander, B., et al.
(author)
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A facile way of making inexpensive rigid and soft protein biofoams with rapid liquid absorption
- 2018
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In: Industrial crops and products (Print). - : Elsevier. - 0926-6690 .- 1872-633X. ; 119, s. 41-48
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Journal article (peer-reviewed)abstract
- A novel and facile method to produce inexpensive protein biofoams suitable for sponge applications is presented. The protein used in the study was wheat gluten (WG), readily available as a by/co-product, but the method is expected to work for other cross-linkable proteins. The foams were obtained by high-speed stirring of pristine WG powder in water at room temperature followed by drying. Glutaraldehyde was used to crosslink the foam material in order to stabilize the dispersion, reduce its tackiness and improve the strength of the final foam. The foams were of medium to high density and absorbed readily both hydrophobic and hydrophilic liquids. The foam structure, consisting primarily of an open pore/channel system, led to a remarkably fast capillary-driven (pore-filling only) uptake of a hydrophobic liquid (limonene). Essentially all uptake occurred within the first second (to ca. 90% of the dry weight). In a polar liquid (water), the rapid pore-filling occurred in parallel with a more time-dependent swelling of the foam matrix material. Further improvement in the foam strength was achieved by making a denser foam or adding TEMPO-oxidized cellulose nanofibres. Soft foams were obtained by adding glycerol.
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| 4. |
- Besselink, B., et al.
(author)
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D-stability and delay-independent stability of monotone nonlinear systems with max-separable Lyapunov functions
- 2016
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In: 2016 IEEE 55th Conference on Decision and Control, CDC 2016. - : Institute of Electrical and Electronics Engineers (IEEE). - 9781509018376 ; , s. 3172-3177
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Conference paper (peer-reviewed)abstract
- Stability properties of monotone nonlinear systems with max-separable Lyapunov functions are considered in this paper, motivated by the following observations. First, recent results have shown that such Lyapunov functions are guaranteed to exist for asymptotically stable monotone systems on compact sets. Second, it is well-known that, for monotone linear systems, asymptotic stability implies the stronger properties of D-stability and robustness with respect to time-delays. This paper shows that similar properties hold for monotone nonlinear systems that admit max-separable Lyapunov functions. In particular, a notion of D-stability for monotone nonlinear systems and delay-independent stability will be discussed. The theoretical results are illustrated by means of examples.
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| 5. |
- Ceresino, E. B., et al.
(author)
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Impact of gluten separation process and transglutaminase source on gluten based dough properties
- 2019
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In: Food Hydrocolloids. - : Elsevier. - 0268-005X .- 1873-7137. ; 87, s. 661-669
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Journal article (peer-reviewed)abstract
- This study evaluated the effect of the wheat gluten (WG) separation process and transglutaminase (TG) microbial source on WG dough quality, and opportunities to use these factors to tailor dough quality. Two types of gluten (harshly and mildly separated), two types of TG (commercial and novel SB6), and three TG concentrations were evaluated for effects on dough mixing properties, protein structure and solubility. Mildly separated gluten improved dough development parameters, resulting into higher values of most compared with harshly separated gluten. Despite more strongly cross-linked proteins being found in the harshly separated gluten, both gluten types showed similar levels of cross-linking at optimum mixing time, although differences in the secondary protein structure were indicated. Thus, disulfide-sulfhydryl exchange reactions were found to be promoted by mixing, although restrictions on establishment of new bonds because of prior cross-links in the material were clearly indicated. Degree of polymerization in doughs made from mildly separated gluten increased to varying extents with TG addition depending on TG source and concentration. Thus, for the first time, we show that an appropriate combination of WG separation procedure and TG source can be used to tailor gluten dough end-use properties.
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| 6. |
- Ceresino, Elaine B., et al.
(author)
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Transglutaminase from newly isolated Streptomyces sp CBMAI 1617 : Production optimization, characterization and evaluation in wheat protein and dough systems
- 2018
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In: Food Chemistry. - : ELSEVIER SCI LTD. - 0308-8146 .- 1873-7072. ; 241, s. 403-410
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Journal article (peer-reviewed)abstract
- The popularity of transglutaminase (TG) by the food industry and the variation in functionality of this enzyme from different origins, prompted us to isolate and evaluate a high-yielding TG strain. Through the statistical approaches, Plackett-Burman and response surface methodology, a low cost fermentation media was obtained to produce 6.074 +/- 0.019 U mL(-1) of TG from a novel source; Streptomyces sp. CBMAI 1617 (SB6). Its potential exploitation was compared to commonly used TG, from Streptomyces mobaraensis. Biochemical and FT-IR studies indicated differences between SB6 and commercial TG (Biobond (TM) TG-M). Additions of TG to wheat protein and flour based doughs revealed that the dough stretching depended on the wheat protein fraction, TG amount and its origin. A higher degree of cross-linking of glutenins and of inclusion of gliadin in the polymers was seen for SB6 as compared to commercial TG. Thus, our results support the potential of SB6 to tailor wheat protein properties within various food applications.
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| 7. |
- Haralson, Erik, et al.
(author)
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Influence of self heating in a BiCMOS on SOI technology
- 2004
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In: ESSCIRC 2004. - NEW YORK : IEEE. - 0780384784 ; , s. 337-340
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Conference paper (peer-reviewed)abstract
- Self heating in a 0.25mum BiCMOS technology with different isolation structures is characterized. Thermal resistance values for single- and multiple-emitter devices are extracted and reported. The dependence of the thermal resistance on the emitter aspect ratio is critical to take into consideration when determining the isolation scheme for devices. 2-D electro-thermal simulations are performed and compared to experimental results. The impact of metallization on the self-heating in the device is examined through simulations.
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| 8. |
- Johansson, Henrik J., et al.
(author)
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Breast cancer quantitative proteome and proteogenomic landscape
- 2019
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In: Nature Communications. - : NATURE PUBLISHING GROUP. - 2041-1723. ; 10
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Journal article (peer-reviewed)abstract
- In the preceding decades, molecular characterization has revolutionized breast cancer (BC) research and therapeutic approaches. Presented herein, an unbiased analysis of breast tumor proteomes, inclusive of 9995 proteins quantified across all tumors, for the first time recapitulates BC subtypes. Additionally, poor-prognosis basal-like and luminal B tumors are further subdivided by immune component infiltration, suggesting the current classification is incomplete. Proteome-based networks distinguish functional protein modules for breast tumor groups, with co-expression of EGFR and MET marking ductal carcinoma in situ regions of normal-like tumors and lending to a more accurate classification of this poorly defined subtype. Genes included within prognostic mRNA panels have significantly higher than average mRNA-protein correlations, and gene copy number alterations are dampened at the protein-level; underscoring the value of proteome quantification for prognostication and phenotypic classification. Furthermore, protein products mapping to non-coding genomic regions are identified; highlighting a potential new class of tumor-specific immunotherapeutic targets.
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| 9. |
- Malm, B. Gunnar, et al.
(author)
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Implanted collector profile optimization in a SiGeHBT process
- 2001
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In: Solid-State Electronics. - 0038-1101 .- 1879-2405. ; 45:3, s. 399-404
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Journal article (peer-reviewed)abstract
- Optimization of implanted collector doping profiles for a high-speed, low-voltage SiGe HBT process has been investigated experimentally and by device simulations. A low-energy antimony implantation has been combined with a standard selectively implanted collector using phosphorous, to achieve improved control of the collector doping profile. The simulations indicate that the narrow n-type doping peak formed by the antimony implantation allows the cut-off frequency f(T) to be increased without degrading the collector emitter breakdown voltage BVCEO. The fabricated devices demonstrate a highest f(T) of 60 GHz. Depending on the collector profile BVCEO values between 1.5 and 2 V were obtained.
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| 10. |
- Malm, B. Gunnar, et al.
(author)
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Self-heating effects in a BiCMOS on SOI technology for RFIC applications
- 2005
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In: IEEE Transactions on Electron Devices. - : IEEE Press. - 0018-9383 .- 1557-9646. ; 52:7, s. 1423-1428
-
Journal article (peer-reviewed)abstract
- Self-heating in a 0.25 mu m BiCMOS technology with different isolation structures, including shallow and deep trenches on bulk and silicon-on-insulator (SOI) substrates, is characterized experimentally. Thermal resistance values for single- and multifinger emitter devices are extracted and compared to results obtained from two-dimensional, fully coupled electrothermal simulations. The difference in thermal resistance between the investigated isolation structures becomes more important for transistors with a small aspect ratio, i.e., short emitter length. The influence of thermal boundary conditions, including the substrate thermal resistance, the thermal resistance of the first metallization/via layer, and the simulation structure width is investigated. In, the device with full dielectric isolation-deep polysilicon-filled trenches on an SOI substrate-accurate modeling of the heat flow in the metallization is found to be crucial. Furthermore, the simulated structure must be made wide enough to account for the large heat flow in the lateral direction.
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