| 1. |
- Rodríguez-Varela, Ricardo, et al.
(author)
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The genetic history of Scandinavia from the Roman Iron Age to the present
- 2023
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In: Cell. - : Elsevier. - 0092-8674 .- 1097-4172. ; 186:1, s. 32-46
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Journal article (peer-reviewed)abstract
- We investigate a 2,000-year genetic transect through Scandinavia spanning the Iron Age to the present, based on 48 new and 249 published ancient genomes and genotypes from 16,638 modern individuals. We find regional variation in the timing and magnitude of gene flow from three sources: the eastern Baltic, the British-Irish Isles, and southern Europe. British-Irish ancestry was widespread in Scandinavia from the Viking period, whereas eastern Baltic ancestry is more localized to Gotland and central Sweden. In some regions, a drop in current levels of external ancestry suggests that ancient immigrants contributed proportionately less to the modern Scandinavian gene pool than indicated by the ancestry of genomes from the Viking and Medieval periods. Finally, we show that a north-south genetic cline that characterizes modern Scandinavians is mainly due to the differential levels of Uralic ancestry and that this cline existed in the Viking Age and possibly earlier.
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| 2. |
- Antoniou, Antonis C., et al.
(author)
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Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers
- 2011
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In: Human Molecular Genetics. - : Oxford University Press (OUP). - 0964-6906 .- 1460-2083. ; 20:16, s. 3304-3321
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Journal article (peer-reviewed)abstract
- Two single nucleotide polymorphisms (SNPs) at 6q25.1, near the ESR1 gene, have been implicated in the susceptibility to breast cancer for Asian (rs2046210) and European women (rs9397435). A genome-wide association study in Europeans identified two further breast cancer susceptibility variants: rs11249433 at 1p11.2 and rs999737 in RAD51L1 at 14q24.1. Although previously identified breast cancer susceptibility variants have been shown to be associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers, the involvement of these SNPs to breast cancer susceptibility in mutation carriers is currently unknown. To address this, we genotyped these SNPs in BRCA1 and BRCA2 mutation carriers from 42 studies from the Consortium of Investigators of Modifiers of BRCA1/2. In the analysis of 14 123 BRCA1 and 8053 BRCA2 mutation carriers of European ancestry, the 6q25.1 SNPs (r(2) = 0.14) were independently associated with the risk of breast cancer for BRCA1 mutation carriers [ hazard ratio (HR) = 1.17, 95% confidence interval (CI): 1.11-1.23, P-trend = 4.5 x 10(-9) for rs2046210; HR = 1.28, 95% CI: 1.18-1.40, P-trend = 1.3 x 10(-8) for rs9397435], but only rs9397435 was associated with the risk for BRCA2 carriers (HR = 1.14, 95% CI: 1.01-1.28, P-trend = 0.031). SNP rs11249433 (1p11.2) was associated with the risk of breast cancer for BRCA2 mutation carriers (HR = 1.09, 95% CI: 1.02-1.17, P-trend = 0.015), but was not associated with breast cancer risk for BRCA1 mutation carriers (HR = 0.97, 95% CI: 0.92-1.02, P-trend = 0.20). SNP rs999737 (RAD51L1) was not associated with breast cancer risk for either BRCA1 or BRCA2 mutation carriers (P-trend = 0.27 and 0.30, respectively). The identification of SNPs at 6q25.1 associated with breast cancer risk for BRCA1 mutation carriers will lead to a better understanding of the biology of tumour development in these women.
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| 3. |
- Brodd, Sven-Erik & Jonson, Jonas & Bergman, Kerstin & Cavallin, Lars & Roelvink, Henrik & Corsten, Angela
(author)
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Kyrkan som sakrament. En rapport om kyrkosyn. Stockholms katolska stift och Svenska kyrkan
- 1999
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In: Kirchliche Zeitgeschichte. Halbjahresschrift für Kirchliche Zeitgeschichte. - : Uppsala.
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Journal article (other academic/artistic)abstract
- En text utgiven av den officiella samtalsgruppen mellan Svenska kyrkan och Stockholms katolska stift. Den diskuterar och tar ställning till en i västerländsk teologi relativt nya föreställningen om kyrkan som ett slags grundsakrament utifrån vilket såväl
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| 4. |
- Johansson, Wilhelm, et al.
(author)
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Transparent TiO2 and ZnO Thin Films on Glass for UV Protection of PV Modules
- 2020
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In: American Ceramic Society Bulletin. - : American Ceramic Society Inc.. - 0002-7812 .- 1945-2705. ; 99:4, s. 26-29
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Journal article (other academic/artistic)abstract
- To stabilize the global temperature and mitigate climate change, the emission of anthropogenic greenhouse gases will have to be greatly reduced. To make it possible, the energy sector will have to transfer from fossil energy to environmentally friendly and carbon neutral sources.
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| 5. |
- Johansson, Wilhelm, et al.
(author)
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Transparent TiO2 and ZnO Thin Films on Glass for UV Protection of PV Modules
- 2019
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In: Frontiers in Materials. - Lausanne, Switzerland : Frontiers Media S.A.. - 2296-8016. ; 6
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Journal article (peer-reviewed)abstract
- Failure of PV modules frequently occurs as a result of degradation of their encapsulation material by destructive UV radiation. Both the life expectancy and efficiency of PV modules can be improved by reducing the transmittance of the destructive UV radiation through the cover glass without compromising the transmittance in the visible wavelength region. In addition, if the absorbed UV photons can be down-shifted to wavelengths that can be more efficiently converted to electrical energy, an additional increase of the PV efficiency could be achieved. In this study we have investigated transparent ZnO and TiO2 thin films deposited by spray pyrolysis on soda lime silicate float glass as functional layers on PV cover glass. The optical bandgap, UV-cutoff, UV-Vis transmittance, reflectivity (total and diffuse) and photoluminescence have been determined. The ZnO coating shifted the optical bandgap to longer wavelengths, resulting in a reduction of the transmittance of destructive UV radiation by up to ∼85%. Distinct photoluminescence peaks at 377 nm and at 640 nm were observed for one of the ZnO samples. The TiO2 coated glasses also showed an increased UV cutoff, which resulted in a reduction of transmittance of destructive UV radiation by up to 75%. However, no photoluminescence peaks could be observed from the TiO2 films with 325 nm excitation laser, which can be explained by the fact that only indirect interband transitions are accessible at this excitation wavelength. Deposition of both ZnO and TiO2 coatings resulted in a reduction of the transmitted light convertible by PV modules, by up to 12.3 and 21.8%, respectively. The implication of the results is discussed in terms of lifetime expectancy and efficiency of PV modules.
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| 6. |
- Reifarth, R., et al.
(author)
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Nuclear astrophysics with radioactive ions at FAIR
- 2016
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In: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 665:1
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Conference paper (peer-reviewed)abstract
- The nucleosynthesis of elements beyond iron is dominated by neutron captures in the s and r processes. However, 32 stable, proton-rich isotopes cannot be formed during those processes, because they are shielded from the s-process flow and r-process beta-decay chains. These nuclei are attributed to the p and rp process. For all those processes, current research in nuclear astrophysics addresses the need for more precise reaction data involving radioactive isotopes. Depending on the particular reaction, direct or inverse kinematics, forward or time-reversed direction are investigated to determine or at least to constrain the desired reaction cross sections. The Facility for Antiproton and Ion Research (FAIR) will offer unique, unprecedented opportunities to investigate many of the important reactions. The high yield of radioactive isotopes, even far away from the valley of stability, allows the investigation of isotopes involved in processes as exotic as the r or rp processes.
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