| 1. |
- Arbyn, M, et al.
(författare)
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Methods for screening and diagnosis
- 2007
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Ingår i: 2nd edition of the EU Guidelines for cervical cancer screening. - 9789279076985 ; , s. 69-141
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 2. |
- Karlsson, Johan, 1979-, et al.
(författare)
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Biodegradable Polymeric Nanoparticles for Therapeutic Cancer Treatments
- 2018
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Ingår i: Annual Review Of Chemical And Biomolecular Engineering, Vol 9. - : ANNUAL REVIEWS. - 1947-5446 .- 1947-5438. - 9780824352097 ; , s. 105-127
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Bokkapitel (refereegranskat)abstract
- Polymeric nanoparticles have tremendous potential to improve the efficacy of therapeutic cancer treatments by facilitating targeted delivery to a desired site. The physical and chemical properties of polymers can be tuned to accomplish delivery across the multiple biological barriers required to reach diverse subsets of cells. The use of biodegradable polymers as nanocarriers is especially attractive, as these materials can be designed to break down in physiological conditions and engineered to exhibit triggered functionality when at a particular location or activated by an external source. We present how biodegradable polymers can be engineered as drug delivery systems to target the tumor microenvironment in multiple ways. These nanomedicines can target cancer cells directly, the blood vessels that supply the nutrients and oxygen that support tumor growth, and immune cells to promote anticancer immunotherapy.
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| 3. |
- Ben-Akiva, Elana, et al.
(författare)
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Delivery strategies for ex vivo and in vivo T-cell reprogramming
- 2022
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Ingår i: Systemic Drug Delivery Strategies. - : Academic Press. - 9780323857819 ; , s. 31-62
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- In recent years, the immune system has increasingly been recognized as a critical component to understanding cancer progression and cellular microenvironments. This has led to massive growth in the field of cancer immunotherapy, in which the patient's natural defense mechanisms are harnessed and enhanced to fight cancer. In this field, T-cell engineering has been the most widely studied and developed approach, with checkpoint inhibitors like anti-PD-1 antibody recently showing impressive clinical success for solid tumors and ex vivo engineering of chimeric antigen receptor T-cells making a significant impact on liquid tumors. There has been continued basic and translational research interest in developing engineering technologies for delivery of therapeutic agents to induce T-cell reprogramming both ex vivo and in vivo for cancer immunotherapy. In this chapter, delivery technologies that provide surface stimulation to T-cells (outside-in) as well as technologies that deliver intracellular mediators to T-cells (inside-out) for reprogramming to enhance anti-cancer activity are discussed.
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| 4. |
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| 5. |
- Richardson, Jeremy J., et al.
(författare)
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The concept of policy style
- 2013
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Ingår i: Policy styles in Western Europe. - : Routledge. - 9780203082010 - 9780415641326 - 9780415641319 ; , s. 1-16
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Bokkapitel (refereegranskat)
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| 6. |
- Zlatev, Jordan, et al.
(författare)
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Idiomatic entrenchment and semantic priming
- 2004
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Ingår i: Linguagem, Cultura e Cognição. - Coimbra : Almedina. - 9724022641 - 9724023036 ; , s. 309-334
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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