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KTH Utbildningar 2027/2028
- 2017
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Konstnärligt arbeteabstract
- I projektet Framtidens KTH-utbildningar har vi tagit fram förslag på hur vår verksamhet skulle kunna se ut för studenter, lärare, alumner och arbetsgivare – eller vad de kommer att vara. Visioner blir ofta luddiga så vi har istället skapat konkreta bilder som vi hoppas öppnar för samtal och ett vidare arbete med utbildningar för läsåret 2027/2028 då KTH firar tvåhundraårsjubileum.Denna katalog är endast till för idévärlden och innebär inget åtagande för KTH att erbjuda de utbildningar eller koncept som beskrivs. Men det är tillåtet att önska sig dem.
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| 4. |
- Ahlquist, Mårten, et al.
(författare)
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Rhodium(I) hydrogenation in water : Kinetic studies and the detection of an intermediate using C-13{H-1} PHIPNMR spectroscopy
- 2007
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Ingår i: Inorganica Chimica Acta. - : Elsevier BV. - 0020-1693 .- 1873-3255. ; 360:5, s. 1621-1627
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Tidskriftsartikel (refereegranskat)abstract
- The mechanism for hydrogenation of dimethylmaleate in water using cationic rhodium complexes with water-soluble bi-dentate phosphines has been investigated using kinetics and a novel method for the indirect detection of intermediates in catalytic hydrogenation reactions, whereby a late intermediate was detected. A mechanism is proposed involving fast, irreversible substrate binding followed by a rate-determining reaction with dihydrogen.
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- Alijagic, Andi, 1992-, et al.
(författare)
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A Novel Nanosafety Approach Using Cell Painting, Metabolomics, and Lipidomics Captures the Cellular and Molecular Phenotypes Induced by the Unintentionally Formed Metal-Based (Nano)Particles
- 2023
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Ingår i: Cells. - : MDPI. - 2073-4409. ; 12:2
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Tidskriftsartikel (refereegranskat)abstract
- Additive manufacturing (AM) or industrial 3D printing uses cutting-edge technologies and materials to produce a variety of complex products. However, the effects of the unintentionally emitted AM (nano)particles (AMPs) on human cells following inhalation, require further investigations. The physicochemical characterization of the AMPs, extracted from the filter of a Laser Powder Bed Fusion (L-PBF) 3D printer of iron-based materials, disclosed their complexity, in terms of size, shape, and chemistry. Cell Painting, a high-content screening (HCS) assay, was used to detect the subtle morphological changes elicited by the AMPs at the single cell resolution. The profiling of the cell morphological phenotypes, disclosed prominent concentration-dependent effects on the cytoskeleton, mitochondria, and the membranous structures of the cell. Furthermore, lipidomics confirmed that the AMPs induced the extensive membrane remodeling in the lung epithelial and macrophage co-culture cell model. To further elucidate the biological mechanisms of action, the targeted metabolomics unveiled several inflammation-related metabolites regulating the cell response to the AMP exposure. Overall, the AMP exposure led to the internalization, oxidative stress, cytoskeleton disruption, mitochondrial activation, membrane remodeling, and metabolic reprogramming of the lung epithelial cells and macrophages. We propose the approach of integrating Cell Painting with metabolomics and lipidomics, as an advanced nanosafety methodology, increasing the ability to capture the cellular and molecular phenotypes and the relevant biological mechanisms to the (nano)particle exposure.
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- Andersson, Thord, et al.
(författare)
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Consistent intensity inhomogeneity correction in water-fat MRI
- 2015
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Ingår i: Journal of Magnetic Resonance Imaging. - : Wiley-Blackwell. - 1053-1807 .- 1522-2586. ; 42:2
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To quantitatively and qualitatively evaluate the water-signal performance of the consistent intensity inhomogeneity correction (CIIC) method to correct for intensity inhomogeneitiesMETHODS: Water-fat volumes were acquired using 1.5 Tesla (T) and 3.0T symmetrically sampled 2-point Dixon three-dimensional MRI. Two datasets: (i) 10 muscle tissue regions of interest (ROIs) from 10 subjects acquired with both 1.5T and 3.0T whole-body MRI. (ii) Seven liver tissue ROIs from 36 patients imaged using 1.5T MRI at six time points after Gd-EOB-DTPA injection. The performance of CIIC was evaluated quantitatively by analyzing its impact on the dispersion and bias of the water image ROI intensities, and qualitatively using side-by-side image comparisons.RESULTS: CIIC significantly ( P1.5T≤2.3×10-4,P3.0T≤1.0×10-6) decreased the nonphysiological intensity variance while preserving the average intensity levels. The side-by-side comparisons showed improved intensity consistency ( Pint≤10-6) while not introducing artifacts ( Part=0.024) nor changed appearances ( Papp≤10-6).CONCLUSION: CIIC improves the spatiotemporal intensity consistency in regions of a homogenous tissue type.
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- Aspeborg, Henrik, 1970-, et al.
(författare)
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Vegetabile material, plants and a method of producing a plant having altered lignin properties
- 2008
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Patent (populärvet., debatt m.m.)abstract
- The present invention is related to a set of genes, which when modified in plants gives altered lignin properties. The invention provides DNA construct such as a vector useful in the method of the invention. Further, the invention relates to a plant cell or plant progeny of the plants and wood produced by the plants according to the invention Lower lignin levels will result in improved saccharification for bio-refining and ethanol production and improved pulp and paper. Increased lignin levels will utilise lignin properties for energy production. The genes and DNA constructs may be used for the identification of plants having altered lignin characteristics as compared to the wild-type. According to the invention genes and DNA constructs may also be used as candidate genes in marker assisted breeding.
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| 8. |
- Bengtsson, Magnus, et al.
(författare)
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Fluorescence lidar imaging of fungal growth on high-voltage outdoor composite insulators
- 2005
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Ingår i: Optics and Lasers in Engineering. - : Elsevier BV. - 0143-8166 .- 1873-0302. ; 43:6, s. 624-632
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Tidskriftsartikel (refereegranskat)abstract
- Remote fluorescence imaging of fungal growth on polymeric high-voltage insulators was performed using a mobile lidar system with a laser wavelength of 355 nm. Insulator areas contaminated by fungal growth could be distinguished from clean surfaces and readily be imaged. The experiments were supported by detailed spectral studies performed in laboratory using a fibre-optic fluorosensor incorporating an optical multi-channel analyser system (OMA) and a nitrogen laser emitting radiation at 33 7 nm.
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| 9. |
- Bengtsson, Magnus, et al.
(författare)
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Fungus covered insulator materials studied with laser-induced fluorescence and principal component analysis
- 2005
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Ingår i: Applied Spectroscopy. - : SAGE Publications. - 0003-7028 .- 1943-3530. ; 59:8, s. 1037-1041
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Tidskriftsartikel (refereegranskat)abstract
- A method combining laser-induced fluorescence and principal component analysis to detect and discriminate between algal and fungal growth on insulator materials has been studied. Eight fungal cultures and four insulator materials have been analyzed. Multivariate classifications were utilized to characterize the insulator material, and fungal growth could readily be distinguished from a clean surface. The results of the principal component analyses make it possible to distinguish between algae infected, fungi infected, and clean silicone rubber materials. The experiments were performed in the laboratory using a fiber-optic fluorosensor that consisted of a nitrogen laser and an optical multi-channel analyzer system.
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| 10. |
- Björk, Gunnar, et al.
(författare)
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Proposed Implementation of "Non-Physical" Four-Dimensional Polarization Rotations
- 2016
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Ingår i: Journal of Lightwave Technology. - : IEEE. - 0733-8724 .- 1558-2213. ; 34:14, s. 3317-3322
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Tidskriftsartikel (refereegranskat)abstract
- Recently one of us proposed a new formalism for modeling electromagnetic wave transformations for coherent communication using a real, four-vector description instead of the conventionally used Jones calculus or the Mueller matrices. The four-vector can then handle all superpositions of two orthogonal polarization basis and two orthogonal time bases (e.g., the in-phase and quadrature phase). In developing this formulation it was found that to provide a general but minimal framework for such rotations, it is natural to divide the six generators of four-dimensional (4d) rotations into two groups of three generators, the right-and the left-isoclinic matrices. Of the six transformations these generators define, it was furthermore found that four of them are readily implemented by linear optical components, while two of then were impossible to implement by such means. In this paper, we detail the reason these two "unphysical" rotations cannot be implemented with linear optics. We also suggest how they can be implemented, but at a cost in the signal-to-noise ratio, and give this minimum cost.
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