SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Kaufmann Susanne) "

Sökning: WFRF:(Kaufmann Susanne)

  • Resultat 1-5 av 5
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Cossarizza, Andrea, et al. (författare)
  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
  • 2019
  • Ingår i: European Journal of Immunology. - WILEY. - 0014-2980 .- 1521-4141. ; 49:10, s. 1457-1973
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in murine and human cells. The latest flow cytometry techniques and applications are also described, featuring examples of the data that can be generated and, importantly, how the data can be analysed. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid, all written and peer-reviewed by leading experts in the field, making this an essential research companion.</p>
  •  
2.
  • Dunning, Alison M, et al. (författare)
  • Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.
  • 2016
  • Ingår i: Nature Genetics. - Nature Publishing Group. - 1546-1718.
  • Tidskriftsartikel (refereegranskat)abstract
    • We analyzed 3,872 common genetic variants across the ESR1 locus (encoding estrogen receptor α) in 118,816 subjects from three international consortia. We found evidence for at least five independent causal variants, each associated with different phenotype sets, including estrogen receptor (ER(+) or ER(-)) and human ERBB2 (HER2(+) or HER2(-)) tumor subtypes, mammographic density and tumor grade. The best candidate causal variants for ER(-) tumors lie in four separate enhancer elements, and their risk alleles reduce expression of ESR1, RMND1 and CCDC170, whereas the risk alleles of the strongest candidates for the remaining independent causal variant disrupt a silencer element and putatively increase ESR1 and RMND1 expression.
  •  
3.
  • Dunning, Alison M., et al. (författare)
  • Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
  • 2016
  • Ingår i: Nature Genetics. - 1061-4036 .- 1546-1718. ; 48:4, s. 374-386
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>We analyzed 3,872 common genetic variants across the ESR1 locus (encoding estrogen receptor a) in 118,816 subjects from three international consortia. We found evidence for at least five independent causal variants, each associated with different phenotype sets, including estrogen receptor (ER+ or ER-) and human ERBB2 (HER2(+) or HER2(-)) tumor subtypes, mammographic density and tumor grade. The best candidate causal variants for ER-tumors lie in four separate enhancer elements, and their risk alleles reduce expression of ESR1, RMND1 and CCDC170, whereas the risk alleles of the strongest candidates for the remaining independent causal variant disrupt a silencer element and putatively increase ESR1 and RMND1 expression.</p>
  •  
4.
  • Fahrenkrog, Felix, et al. (författare)
  • Impact Assessment of Developed Applications – Overall interactIVe Assessment
  • 2013
  • Rapport (övrigt vetenskapligt)abstract
    • interactIVe introduces active intervention safety systems in order to increase traffic safety. The interactIVe functions are – depending on their purpose – able to brake and steer autonomously. Furthermore, the driver is continuously supported by interactIVe assistance systems which warn the driver in potentially dangerous situations. Seven demonstrator vehicles – six passenger cars of different vehicle classes and one truck - are built up in interactIVe to develop, test, and evaluate the next generation of safety systems. The three vertical subprojects in interactIVe SECONDS, INCA and EMIC have developed 11 different functions with a wide range of target areas. The developed advanced driver assistance systems (ADAS) comprise the following systems: • SP4 “SECONDS” dealing with functions, which support the driver continuously in the driving process. These functions should not only support the driver in dangerous situations, but help the driver to avoid them. • SP5 “INCA” dealing with functions, which combine longitudinal and lateral control of the vehicle in order to prevent imminent accidents. The INCA functions’ focus is not only on the collision avoidance in rear-end conflicts, but also on other types of conflicts, such as blind-spot and road departure situations. • SP6 “EMIC” deals with critical pre-crash applications, where collision mitigation can be realised at a reasonable cost. In order to evaluate the ADAS developed, an evaluation framework is required. Therefore, the subproject “Evaluation and Legal Aspects” is part of the interactIVe project, which has as main objective to provide this framework and to support the vertical subprojects in their evaluation work. The evaluation of the interactIVe functions has been divided into three main categories: • Technical Assessment to evaluate the performance of the developed functions and collect information and data for safety impact assessment. • User-Related Assessment to assess the functions from the user perspective, and also to provide further input to the safety impact assessment. • Impact Assessment to estimate how and how much the functions influence traffic safety. In this deliverable, the results of the evaluation in interactIVe are presented.
  •  
5.
  • Udechukwu, Obiora, et al. (författare)
  • Notes From the Field: Tradition
  • 2013
  • Ingår i: The Art Bulletin. - 0004-3079 .- 1559-6478. ; 95:4, s. 526-527
  • Tidskriftsartikel (övrigt vetenskapligt)
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-5 av 5
 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy