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Dismantling, optimising, and personalising internet cognitive behavioural therapy for depression: a systematic review and component network meta-analysis using individual data
- Furukawa, T. A. (author)
- Suganuma, A. (author)
- Ostinelli, E. G. (author)
- show more...
- Andersson, G. (author)
- Beevers, C. G. (author)
- Shumake, J. (author)
- Berger, T. (author)
- Boele, F. W. (author)
- Buntrock, C. (author)
- Carlbring, P. (author)
- Choi, I. (author)
- Christensen, H. (author)
- Mackinnon, A. (author)
- Dahne, J. (author)
- Huibers, M. J. H. (author)
- Ebert, D. D. (author)
- Farrer, L. (author)
- Forand, N. R. (author)
- Strunk, D. R. (author)
- Ezawa, I. D. (author)
- Forsell, E. (author)
- Kaldo, V. (author)
- Geraedts, A. (author)
- Gilbody, S. (author)
- Littlewood, E. (author)
- Brabyn, S. (author)
- Hadjistavropoulos, H. D. (author)
- Schneider, L. H. (author)
- Johansson, R. (author)
- Kenter, R. (author)
- Bjorkelund, C. (author)
- Kleiboer, A. (author)
- Riper, H. (author)
- Klein, J. P. (author)
- Schroder, J. (author)
- Meyer, B. (author)
- Moritz, S. (author)
- Bucker, L. (author)
- Lintvedt, O. (author)
- Johansson, P. (author)
- Lundgren, J. (author)
- Milgrom, J. (author)
- Gemmill, A. W. (author)
- Mohr, D. C. (author)
- Montero-Marin, J. (author)
- Garcia-Campayo, J. (author)
- Nobis, S. (author)
- Zarski, A. C. (author)
- O'Moore, K. (author)
- Williams, A. D. (author)
- Newby, J. M. (author)
- Perini, S. (author)
- Phillips, R. (author)
- Schneider, J. (author)
- Pots, W. (author)
- Pugh, N. E. (author)
- Richards, D. (author)
- Rosso, I. M. (author)
- Rauch, S. L. (author)
- Sheeber, L. B. (author)
- Smith, J. (author)
- Spek, V. (author)
- Pop, V. J. (author)
- Unlu, B. (author)
- van Bastelaar, K. M. P. (author)
- van Luenen, S. (author)
- Garnefski, N. (author)
- Kraaij, V. (author)
- Vernmark, K. (author)
- Warmerdam, L. (author)
- van Straten, A. (author)
- Zagorscak, P. (author)
- Knaevelsrud, C. (author)
- Heinrich, M. (author)
- Miguel, C. (author)
- Cipriani, A. (author)
- Efthimiou, O. (author)
- Karyotaki, E. (author)
- Cuijpers, P. (author)
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- (creator_code:org_t)
- Elsevier BV, 2021
- 2021
- English.
- In: Lancet Psychiatry. - : Elsevier BV. - 2215-0374 .- 2215-0366. ; 8:6, s. 500-511
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Findings We identified 76 RCTs, including 48 trials contributing individual participant data (11 704 participants) and 28 trials with aggregate data (6474 participants). The participants' weighted mean age was 42.0 years and 12 406 (71%) of 17 521 reported were women. There was suggestive evidence that behavioural activation might be beneficial (iMD -1.83 [95% credible interval (CrI) -2.90 to -0.80]) and that relaxation might be harmful (1.20 [95% CrI 0.17 to 2.27]). Baseline severity emerged as the strongest prognostic factor for endpoint depression. Combining human and automated encouragement reduced dropouts from treatment (incremental odds ratio, 0.32 [95% CrI 0.13 to 0.93]). The risk of bias was low for the randomisation process, missing outcome data, or selection of reported results in most of the included studies, uncertain for deviation from intended interventions, and high for measurement of outcomes. There was moderate to high heterogeneity among the studies and their components. 511
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Keyword
- participant data
- interventions
- inconsistency
- anxiety
- Psychiatry
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
- Furukawa, T. A.
- Suganuma, A.
- Ostinelli, E. G.
- Andersson, G.
- Beevers, C. G.
- Shumake, J.
- show more...
- Berger, T.
- Boele, F. W.
- Buntrock, C.
- Carlbring, P.
- Choi, I.
- Christensen, H.
- Mackinnon, A.
- Dahne, J.
- Huibers, M. J. H ...
- Ebert, D. D.
- Farrer, L.
- Forand, N. R.
- Strunk, D. R.
- Ezawa, I. D.
- Forsell, E.
- Kaldo, V.
- Geraedts, A.
- Gilbody, S.
- Littlewood, E.
- Brabyn, S.
- Hadjistavropoulo ...
- Schneider, L. H.
- Johansson, R.
- Kenter, R.
- Kivi, Marie
- Bjorkelund, C.
- Kleiboer, A.
- Riper, H.
- Klein, J. P.
- Schroder, J.
- Meyer, B.
- Moritz, S.
- Bucker, L.
- Lintvedt, O.
- Johansson, P.
- Lundgren, J.
- Milgrom, J.
- Gemmill, A. W.
- Mohr, D. C.
- Montero-Marin, J ...
- Garcia-Campayo, ...
- Nobis, S.
- Zarski, A. C.
- O'Moore, K.
- Williams, A. D.
- Newby, J. M.
- Perini, S.
- Phillips, R.
- Schneider, J.
- Pots, W.
- Pugh, N. E.
- Richards, D.
- Rosso, I. M.
- Rauch, S. L.
- Sheeber, L. B.
- Smith, J.
- Spek, V.
- Pop, V. J.
- Unlu, B.
- van Bastelaar, K ...
- van Luenen, S.
- Garnefski, N.
- Kraaij, V.
- Vernmark, K.
- Warmerdam, L.
- van Straten, A.
- Zagorscak, P.
- Knaevelsrud, C.
- Heinrich, M.
- Miguel, C.
- Cipriani, A.
- Efthimiou, O.
- Karyotaki, E.
- Cuijpers, P.
- show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Psychiatry
- Articles in the publication
- Lancet Psychiatr ...
- By the university
- University of Gothenburg
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