SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Kim Sung Won) "

Sökning: WFRF:(Kim Sung Won)

  • Resultat 1-10 av 34
  • [1]234Nästa
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • An, Junghwa, et al. (författare)
  • Permanent Genetic Resources added to Molecular Ecology Resources Database 1 October 2009-30 November 2009
  • 2010
  • Ingår i: Molecular Ecology Resources. - 1755-098X. ; 10:2, s. 404-408
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>This article documents the addition of 411 microsatellite marker loci and 15 pairs of Single Nucleotide Polymorphism (SNP) sequencing primers to the Molecular Ecology Resources Database. Loci were developed for the following species: Acanthopagrus schlegeli, Anopheles lesteri, Aspergillus clavatus, Aspergillus flavus, Aspergillus fumigatus, Aspergillus oryzae, Aspergillus terreus, Branchiostoma japonicum, Branchiostoma belcheri, Colias behrii, Coryphopterus personatus, Cynogolssus semilaevis, Cynoglossus semilaevis, Dendrobium officinale, Dendrobium officinale, Dysoxylum malabaricum, Metrioptera roeselii, Myrmeciza exsul, Ochotona thibetana, Neosartorya fischeri, Nothofagus pumilio, Onychodactylus fischeri, Phoenicopterus roseus, Salvia officinalis L., Scylla paramamosain, Silene latifo, Sula sula, and Vulpes vulpes. These loci were cross-tested on the following species: Aspergillus giganteus, Colias pelidne, Colias interior, Colias meadii, Colias eurytheme, Coryphopterus lipernes, Coryphopterus glaucofrenum, Coryphopterus eidolon, Gnatholepis thompsoni, Elacatinus evelynae, Dendrobium loddigesii Dendrobium devonianum, Dysoxylum binectariferum, Nothofagus antarctica, Nothofagus dombeyii, Nothofagus nervosa, Nothofagus obliqua, Sula nebouxii, and Sula variegata. This article also documents the addition of 39 sequencing primer pairs and 15 allele specific primers or probes for Paralithodes camtschaticus.</p>
  •  
2.
  • Kim, Jeemin, et al. (författare)
  • Millimeter-Wave Interference Avoidance via Building-Aware Associations
  • 2018
  • Ingår i: IEEE Access. - IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 2169-3536. ; 6, s. 10618-10634
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>Signal occlusion by building blockages is a double-edged sword for the performance of millimeter-wave (mmW) communication networks. Buildings may dominantly attenuate the useful signals, especially when mmW base stations (BSs) are sparsely deployed compared with the building density. In the opposite BS deployment, buildings can block the undesired interference. To enjoy only the benefit, we propose a building-aware association scheme that adjusts the directional BS association bias of the user equipments (UEs), based on a given building density and the concentration of UE locations around the buildings. The association of each BS can thereby be biased: 1) toward the UEs located against buildings for avoiding interference to other UEs or 2) toward the UEs providing their maximum reference signal received powers. The proposed association scheme is optimized to maximize the downlink average data rate derived by stochastic geometry. Its effectiveness is validated by simulation using real building statistics.</p>
  •  
3.
  • Milne, Roger L, et al. (författare)
  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
  • 2017
  • Ingår i: Nature Genetics. - 1061-4036 .- 1546-1718. ; 49:12, s. 1767-1778
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease. We conducted a GWAS using 21,468 ER-negative cases and 100,594 controls combined with 18,908 BRCA1 mutation carriers (9,414 with breast cancer), all of European origin. We identified independent associations at P &lt; 5 × 10-8 with ten variants at nine new loci. At P &lt; 0.05, we replicated associations with 10 of 11 variants previously reported in ER-negative disease or BRCA1 mutation carrier GWAS and observed consistent associations with ER-negative disease for 105 susceptibility variants identified by other studies. These 125 variants explain approximately 16% of the familial risk of this breast cancer subtype. There was high genetic correlation (0.72) between risk of ER-negative breast cancer and breast cancer risk for BRCA1 mutation carriers. These findings may lead to improved risk prediction and inform further fine-mapping and functional work to better understand the biological basis of ER-negative breast cancer.</p>
  •  
4.
  • Sung, Ki Won, 1913-, et al. (författare)
  • PriMO-5G : Making firefighting smarter with immersive videos through 5G
  • 2019
  • Ingår i: Proceedings of IEEE 5G World Forum, 5GWF 2019. - IEEE. - 9781728136271 ; s. 280-285
  • Konferensbidrag (refereegranskat)abstract
    • <p>In this paper, we introduce PriMO-5G which is an EU-Korea collaboration project studying the use of 5G technologies and unmanned aerial vehicles (UAVs) or drones to enhance the safety and efficiency of firefighting operations. We start by describing envisaged use cases of smart firefighting focusing on how the 5G communications with drones can help the firefighting. Inspired by the use cases, we identify several research challenges that call for new solutions in 5G radios and cores for mission-critical services. Then, a discussion of a new framework for defining key performance indicators (KPIs) follows. Finally, we introduce our effort and future plans for the demonstration of the technologies that the PriMO-5G develops.</p>
  •  
5.
  • Akiyama, Kazunori, et al. (författare)
  • First M87 Event Horizon Telescope Results. IV. Imaging the Central Supermassive Black Hole
  • 2019
  • Ingår i: Astrophysical Journal Letters. - 2041-8213 .- 2041-8205. ; 875:1
  • Tidskriftsartikel (refereegranskat)abstract
    • We present the first Event Horizon Telescope (EHT) images of M87, using observations from April 2017 at 1.3 mm wavelength. These images show a prominent ring with a diameter of similar to 40 mu as, consistent with the size and shape of the lensed photon orbit encircling the "shadow" of a supermassive black hole. The ring is persistent across four observing nights and shows enhanced brightness in the south. To assess the reliability of these results, we implemented a two-stage imaging procedure. In the first stage, four teams, each blind to the others' work, produced images of M87 using both an established method (CLEAN) and a newer technique (regularized maximum likelihood). This stage allowed us to avoid shared human bias and to assess common features among independent reconstructions. In the second stage, we reconstructed synthetic data from a large survey of imaging parameters and then compared the results with the corresponding ground truth images. This stage allowed us to select parameters objectively to use when reconstructing images of M87. Across all tests in both stages, the ring diameter and asymmetry remained stable, insensitive to the choice of imaging technique. We describe the EHT imaging procedures, the primary image features in M87, and the dependence of these features on imaging assumptions.
6.
  • Akiyama, Kazunori, et al. (författare)
  • First M87 Event Horizon Telescope Results. V. Physical Origin of the Asymmetric Ring
  • 2019
  • Ingår i: Astrophysical Journal Letters. - 2041-8213 .- 2041-8205. ; 875:1
  • Tidskriftsartikel (refereegranskat)abstract
    • The Event Horizon Telescope (EHT) has mapped the central compact radio source of the elliptical galaxy M87 at 1.3 mm with unprecedented angular resolution. Here we consider the physical implications of the asymmetric ring seen in the 2017 EHT data. To this end, we construct a large library of models based on general relativistic magnetohydrodynamic (GRMHD) simulations and synthetic images produced by general relativistic ray tracing. We compare the observed visibilities with this library and confirm that the asymmetric ring is consistent with earlier predictions of strong gravitational lensing of synchrotron emission from a hot plasma orbiting near the black hole event horizon. The ring radius and ring asymmetry depend on black hole mass and spin, respectively, and both are therefore expected to be stable when observed in future EHT campaigns. Overall, the observed image is consistent with expectations for the shadow of a spinning Kerr black hole as predicted by general relativity. If the black hole spin and M87's large scale jet are aligned, then the black hole spin vector is pointed away from Earth. Models in our library of non-spinning black holes are inconsistent with the observations as they do not produce sufficiently powerful jets. At the same time, in those models that produce a sufficiently powerful jet, the latter is powered by extraction of black hole spin energy through mechanisms akin to the Blandford-Znajek process. We briefly consider alternatives to a black hole for the central compact object. Analysis of existing EHT polarization data and data taken simultaneously at other wavelengths will soon enable new tests of the GRMHD models, as will future EHT campaigns at 230 and 345 GHz.
7.
  • Akiyama, Kazunori, et al. (författare)
  • First M87 Event Horizon Telescope Results. VI. The Shadow and Mass of the Central Black Hole
  • 2019
  • Ingår i: Astrophysical Journal Letters. - 2041-8213 .- 2041-8205. ; 875:1
  • Tidskriftsartikel (refereegranskat)abstract
    • We present measurements of the properties of the central radio source in M87 using Event Horizon Telescope data obtained during the 2017 campaign. We develop and fit geometric crescent models (asymmetric rings with interior brightness depressions) using two independent sampling algorithms that consider distinct representations of the visibility data. We show that the crescent family of models is statistically preferred over other comparably complex geometric models that we explore. We calibrate the geometric model parameters using general relativistic magnetohydrodynamic (GRMHD) models of the emission region and estimate physical properties of the source. We further fit images generated from GRMHD models directly to the data. We compare the derived emission region and black hole parameters from these analyses with those recovered from reconstructed images. There is a remarkable consistency among all methods and data sets. We find that >50% of the total flux at arcsecond scales comes from near the horizon, and that the emission is dramatically suppressed interior to this region by a factor >10, providing direct evidence of the predicted shadow of a black hole. Across all methods, we measure a crescent diameter of 42 +/- 3 mu as and constrain its fractional width to be
8.
  • Kim, Kwangwoo, et al. (författare)
  • High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci
  • 2015
  • Ingår i: Annals of the Rheumatic Diseases. - 0003-4967 .- 1468-2060. ; 74:3
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>Objective A highly polygenic aetiology and high degree of allele-sharing between ancestries have been well elucidated in genetic studies of rheumatoid arthritis. Recently, the high-density genotyping array Immunochip for immune disease loci identified 14 new rheumatoid arthritis risk loci among individuals of European ancestry. Here, we aimed to identify new rheumatoid arthritis risk loci using Korean-specific Immunochip data. Methods We analysed Korean rheumatoid arthritis case-control samples using the Immunochip and genome-wide association studies (GWAS) array to search for new risk alleles of rheumatoid arthritis with anticitrullinated peptide antibodies. To increase power, we performed a meta-analysis of Korean data with previously published European Immunochip and GWAS data for a total sample size of 9299 Korean and 45 790 European case-control samples. Results We identified eight new rheumatoid arthritis susceptibility loci (TNFSF4, LBH, EOMES, ETS1-FLI1, COG6, RAD51B, UBASH3A and SYNGR1) that passed a genome-wide significance threshold (p&lt;5x10(-8)), with evidence for three independent risk alleles at 1q25/TNFSF4. The risk alleles from the seven new loci except for the TNFSF4 locus (monomorphic in Koreans), together with risk alleles from previously established RA risk loci, exhibited a high correlation of effect sizes between ancestries. Further, we refined the number of single nucleotide polymorphisms (SNPs) that represent potentially causal variants through a trans-ethnic comparison of densely genotyped SNPs. Conclusions This study demonstrates the advantage of dense-mapping and trans-ancestral analysis for identification of potentially causal SNPs. In addition, our findings support the importance of T cells in the pathogenesis and the fact of frequent overlap of risk loci among diverse autoimmune diseases.</p>
  •  
9.
  • Michailidou, Kyriaki, et al. (författare)
  • Association analysis identifies 65 new breast cancer risk loci.
  • 2017
  • Ingår i: Nature. - 0028-0836 .- 1476-4687. ; 551:7678, s. 92-94
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breast cancer risk remains unknown. Here we report the results of a genome-wide association study of breast cancer in 122,977 cases and 105,974 controls of European ancestry and 14,068 cases and 13,104 controls of East Asian ancestry. We identified 65 new loci that are associated with overall breast cancer risk at P &lt; 5 × 10-8. The majority of credible risk single-nucleotide polymorphisms in these loci fall in distal regulatory elements, and by integrating in silico data to predict target genes in breast cells at each locus, we demonstrate a strong overlap between candidate target genes and somatic driver genes in breast tumours. We also find that heritability of breast cancer due to all single-nucleotide polymorphisms in regulatory features was 2-5-fold enriched relative to the genome-wide average, with strong enrichment for particular transcription factor binding sites. These results provide further insight into genetic susceptibility to breast cancer and will improve the use of genetic risk scores for individualized screening and prevention.</p>
  •  
10.
  • Phelan, Catherine M, et al. (författare)
  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.
  • 2017
  • Ingår i: Nature Genetics. - 1061-4036 .- 1546-1718. ; 49:5, s. 680-691
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC cases and 40,941 controls. We identified nine new susceptibility loci for different EOC histotypes: six for serous EOC histotypes (3q28, 4q32.3, 8q21.11, 10q24.33, 18q11.2 and 22q12.1), two for mucinous EOC (3q22.3 and 9q31.1) and one for endometrioid EOC (5q12.3). We then performed meta-analysis on the results for high-grade serous ovarian cancer with the results from analysis of 31,448 BRCA1 and BRCA2 mutation carriers, including 3,887 mutation carriers with EOC. This identified three additional susceptibility loci at 2q13, 8q24.1 and 12q24.31. Integrated analyses of genes and regulatory biofeatures at each locus predicted candidate susceptibility genes, including OBFC1, a new candidate susceptibility gene for low-grade and borderline serous EOC.</p>
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 34
  • [1]234Nästa
Åtkomst
fritt online (6)
Typ av publikation
tidskriftsartikel (26)
konferensbidrag (4)
patent (3)
annan publikation (1)
Typ av innehåll
refereegranskat (30)
övrigt vetenskapligt (9)
Författare/redaktör
Nevanlinna, Heli (6)
John, Esther M (6)
Neuhausen, Susan L (6)
Hamann, Ute (6)
Marti-Vidal, Ivan, 1 ... (5)
Benitez, Javier (5)
visa fler...
Meindl, Alfons (5)
Andrulis, Irene L. (5)
Akiyama, Kazunori, (5)
Alberdi, Antxon, (5)
Alef, Walter, (5)
Ball, David, (5)
Balokovic, Mislav, (5)
Barrett, John, (5)
Bintley, Dan, (5)
Blackburn, Lindy, (5)
Brissenden, Roger, (5)
Britzen, Silke, (5)
Broderick, Avery E., (5)
Bronzwaer, Thomas, (5)
Byun, Do-Young, (5)
Chan, Chi-Kwan, (5)
Chatterjee, Koushik, (5)
Chen, Ming-Tang, (5)
Chen, Yongjun, (5)
Christian, Pierre, (5)
Conway, John, 1963-, (5)
Cordes, James M., (5)
Cui, Yuzhu, (5)
Davelaar, Jordy, (5)
De Laurentis, Mariaf ... (5)
Dempsey, Jessica, (5)
Desvignes, Gregory, (5)
Eatough, Ralph P., (5)
Fromm, Christian M., (5)
Gammie, Charles F., (5)
Garcia, Roberto, (5)
Gentaz, Olivier, (5)
Georgiev, Boris, (5)
Gu, Minfeng, (5)
Hecht, Michael H., (5)
Ho, Luis C., (5)
Huang, Lei, (5)
Inoue, Makoto, (5)
James, David J., (5)
Janssen, Michael, (5)
Jeter, Britton, (5)
Jiang, Wu, (5)
Johnson, Michael D., (5)
Jung, Taehyun, (5)
visa färre...
Lärosäte
Kungliga Tekniska Högskolan (12)
Uppsala universitet (7)
Chalmers tekniska högskola (5)
Lunds universitet (3)
Umeå universitet (2)
Högskolan Väst (2)
visa fler...
Karolinska Institutet (2)
Göteborgs universitet (1)
Luleå tekniska universitet (1)
Linköpings universitet (1)
visa färre...
Språk
Engelska (32)
Forskningsämne (UKÄ/SCB)
Teknik (15)
Naturvetenskap (12)
Medicin och hälsovetenskap (10)
Samhällsvetenskap (2)
Lantbruksvetenskap (1)

År

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy