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Träfflista för sökning "WFRF:(Kuhlmann Berenzon S) "

Sökning: WFRF:(Kuhlmann Berenzon S)

  • Resultat 1-10 av 21
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1.
  • Rehn, Moa, et al. (författare)
  • Highest Vaccine Uptake after School-Based Delivery - A County-Level Evaluation of the Implementation Strategies for HPV Catch-Up Vaccination in Sweden
  • 2016
  • Ingår i: PLoS ONE. - : Public Library of Science. - 1932-6203. ; 11:3, s. 0149857-0149857
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: The Swedish school-based vaccination programme offers HPV vaccine to girls born ≥1999 in 5-6th grade. In 2012, all counties introduced free-of-charge catch-up vaccination campaigns targeting girls born 1993-1998. Varying vaccine uptake in the catch-up group by December 2012 suggested that some implementation strategies were more successful than others. In order to inform future vaccination campaigns, we assessed the impact of different implementation strategies on the county-level catch-up vaccine uptake.METHODS: We conducted an ecological study including all Swedish counties (n = 21), asking regional health offices about the information channels they used and where vaccination of the catch-up target group took place in their counties. The uptake of ≥1 dose by 30 September 2014 was estimated using data from the voluntary national vaccination register. We investigated associations between counties' catch-up vaccine uptake, information channels and vaccination settings by calculating incidence rate ratios (IRR) and 95% confidence intervals (CI), using negative binomial regression models.RESULTS: County level catch-up vaccine uptake varied between 49-84%. All counties offered vaccination through primary health care settings. Apart from this eight (34%) also offered the vaccine in some of their schools, four (19%) in all their schools, and two (10%) in other health care centres. The information channels most frequently used were: information at the national on-line health care consulting web-page (100%), letter/invitations (90%), and advertisement (81%). Counties offering vaccination to girls in all schools and counties offering vaccination in some of their schools, reached higher vaccine uptake compared to counties not offering vaccination in any of their schools (all schools adjusted IRR: 1.3, 95% CI: 1.1-1.5, some schools adjusted IRR: 1.2, 95% CI: 1.1-1.3).CONCLUSION: Counties offering HPV vaccination to catch-up groups in schools reached the highest vaccine uptake. No information channel explained differences in county-level vaccine uptake. Our findings suggest that catch-up vaccination outside the national vaccination program can reach a high uptake at the population level if it is implemented primarily with an organized delivery (e.g. in schools).
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2.
  • Söderström, A, et al. (författare)
  • A large Escherichia coli O157 outbreak in Sweden associated with locally produced lettuce.
  • 2008
  • Ingår i: Foodborne pathogens and disease. - 1556-7125. ; 5:3, s. 339-49
  • Tidskriftsartikel (refereegranskat)abstract
    • In 2005 a large outbreak of verotoxin-producing Escherichia coli (VTEC) occurred in Sweden. Cases were interviewed and cohort and case-control studies were conducted. Microbiological investigations were performed using polymerase chain reaction (PCR) to detect the Shiga-like toxin (Stx) genes followed by cultivation and pulsed-field gel electrophoresis. A total of 135 cases were recorded, including 11 cases of hemolytic uremic syndrome. The epidemiological investigations implicated lettuce as the most likely source of the outbreak, with an OR of 13.0 (CI 2.94-57.5) in the case-control study. The lettuce was irrigated by water from a small stream, and water samples were positive for Stx 2 by PCR. The identical VTEC O157 Stx 2 positive strain was isolated from the cases and in cattle at a farm upstream from the irrigation point. An active surveillance and reporting system was crucial and cooperation between all involved parties was essential for quickly identifying the cause of this outbreak. Handling of fresh greens from farm to table must be improved to minimize the risk of contamination.
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  • Kuhlmann-Berenzon, S., et al. (författare)
  • Accounting for large-scale factors in the study of understory vegetation using a conditional logistic model
  • 2007
  • Ingår i: Environmental and Ecological Statistics. - 1352-8505 .- 1573-3009. ; 14:2, s. 149-159
  • Tidskriftsartikel (refereegranskat)abstract
    • Local-scale and large-scale factors can affect the presence of a species of understory vegetation in the forest. Local-scale factors may be the influence of surrounding trees, while climate and latitude are typically considered large-scale factors. A model for the presence of a species needs to take into account both scales. A conditional logistic model is proposed for those studies where only the local-scale factors are of interest and that avoids estimating the large-scale parameters. Conditioning is carried out by the number of quadrats in the plot where the vegetation is found. As the latter is a sufficient statistic for the large-scale factors, a model free from these parameters is obtained. Data gathered in the permanent sample plots of the 1985-1986 National Forest Inventory of Finland is used for illustration, where the local-scale factor of interest is the influence of the trees, quantified by an index based on the size and location of the trees. The model fitted to Vaccinium vitis-idaea showed a significant and positive influence of Scots pine on the presence of this species, while for Calamagrostis arundinacea, a decrease in the odds ratio was observed due to the influence of Norway spruce.
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5.
  • Veličko, Inga, et al. (författare)
  • Changes in the trend of sexually acquired chlamydia infections in Sweden and the role of testing : a time series analysis.
  • 2020
  • Ingår i: Sexually Transmitted Diseases. - 0148-5717 .- 1537-4521.
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: We investigated notification trends of sexually acquired chlamydia (chlamydia) and its association with testing in Sweden prior to (1992-2004) and after (2009-2018) the discovery of a new variant of C. trachomatis (nvCT).METHODS: We applied monthly time series analysis to study chlamydia trends and annual time series to study chlamydia rates adjusted for testing. We analyzed incidence nationally and by county group (based on able and unable to detect nvCT at time of discovery).RESULTS: We present data on 606,000 cases of chlamydia and 9.9 million persons tested. We found a U-shaped chlamydia trend during 1992-2004 with an overall increase of 83.7% from 1996 onwards. The period 2009-2018 began with a stable trend at a high incidence level followed by a decrease of 19.7% during 2015-2018. Peaks were seen in autumn and through during winter and summer. Similar results were observed by groups of county, though with varying levels of increase and decrease in both time periods. Furthermore, increased testing volume was associated with increased chlamydia rates during the first period (P=0.019), but not the second period.CONCLUSIONS: Our results showed that chlamydia trends during 2009-2018 were not driven by testing, as they were during 1992-2004. This suggests less biased notified chlamydia rates and thus possibly true decrease in chlamydia incidence rates. It is important to adjust case rates for testing intensity, and future research should target other potential factors influencing chlamydia rates.
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6.
  • Velicko, Inga, et al. (författare)
  • Sexual and testing behaviour associated with Chlamydia trachomatis infection : a cohort study in an STI clinic in Sweden
  • 2016
  • Ingår i: BMJ Open. - 2044-6055 .- 2044-6055. ; 6:8
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Genital chlamydia infection (chlamydia) is the most commonly reported sexually transmitted infection (STI) in Sweden. To guide prevention needs, we aimed to investigate factors associated with chlamydia. Methods: A cohort of visitors aged 20-40 years at an urban STI clinic in Sweden was recruited. Behavioural data were collected using a self-administered questionnaire. Self-sampled specimens were tested for chlamydia by a DNA amplification assay. Statistically significant (p<0.05) and epidemiologically relevant covariates were entered in a multivariate Poisson model adjusted for potential confounders (age and gender). Backward stepwise elimination produced a final model. Multiple imputation was used to account for missing values. Results: Out of 2814 respondents, 1436 were men with a chlamydia positivity rate of 12.6% vs 8.9% in women. Lifetime testing for chlamydia and HIV was high (82% and 60%, respectively). Factors significantly associated with chlamydia were: 20-24 years old (adjusted risk ratio (ARR)=2.10, 95% CI 1.21 to 3.65); testing reason: contact with a chlamydia case (ARR=6.55, 95% CI 4.77 to 8.98) and having symptoms (ARR=2.19, 95% CI 1.48 to 3.24); 6-10 sexual partners (ARR=1.53, 95% CI 1.06 to 2.21); last sexual activity 'vaginal sex and oral sex and anal sex and petting' (ARR=1.84, 95% CI 1.09 to 3.10); alcohol use before sex (ARR=1.98, 95% CI 1.10 to 3.57); men with symptoms (ARR=2.09, 95% CI 1.38 to 3.18); tested for chlamydia (ARR=0.72, 95% CI 0.55 to 0.94). Conclusions: Risk factors associated with chlamydia were consistent with previous reports in similar settings and suggest no major changes over time. Increased risk for chlamydia infection associated with high-risk behaviour (eg, alcohol use, increased number of sexual partners) supports the need for behavioural interventions in this population such as promotion of safer sex behaviour (condom use) and testing.
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  • Resultat 1-10 av 21
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