| 1. |
- Lozano, Rafael, et al.
(författare)
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Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
- 2018
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Ingår i: The Lancet. - : Elsevier. - 1474-547X .- 0140-6736. ; 392:10159, s. 2091-2138
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Tidskriftsartikel (refereegranskat)abstract
- Background: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of “leaving no one behind”, it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health-related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990–2017, projected indicators to 2030, and analysed global attainment. Methods: We measured progress on 41 health-related SDG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health-related SDG index, we transformed the value for each indicator on a scale of 0–100, with 0 as the 2·5th percentile and 100 as the 97·5th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the probability of attainment in 2030 calculated from 1000 draws. We also did a global attainment analysis of the feasibility of attaining SDG targets on the basis of past trends. Using 2015 global averages of indicators with defined SDG targets, we calculated the global annualised rates of change required from 2015 to 2030 to meet these targets, and then identified in what percentiles the required global annualised rates of change fell in the distribution of country-level rates of change from 1990 to 2015. We took the mean of these global percentile values across indicators and applied the past rate of change at this mean global percentile to all health-related SDG indicators, irrespective of target definition, to estimate the equivalent 2030 global average value and percentage change from 2015 to 2030 for each indicator. Findings: The global median health-related SDG index in 2017 was 59·4 (IQR 35·4–67·3), ranging from a low of 11·6 (95% uncertainty interval 9·6–14·0) to a high of 84·9 (83·1–86·7). SDG index values in countries assessed at the subnational level varied substantially, particularly in China and India, although scores in Japan and the UK were more homogeneous. Indicators also varied by SDI quintile and sex, with males having worse outcomes than females for non-communicable disease (NCD) mortality, alcohol use, and smoking, among others. Most countries were projected to have a higher health-related SDG index in 2030 than in 2017, while country-level probabilities of attainment by 2030 varied widely by indicator. Under-5 mortality, neonatal mortality, maternal mortality ratio, and malaria indicators had the most countries with at least 95% probability of target attainment. Other indicators, including NCD mortality and suicide mortality, had no countries projected to meet corresponding SDG targets on the basis of projected mean values for 2030 but showed some probability of attainment by 2030. For some indicators, including child malnutrition, several infectious diseases, and most violence measures, the annualised rates of change required to meet SDG targets far exceeded the pace of progress achieved by any country in the recent past. We found that applying the mean global annualised rate of change to indicators without defined targets would equate to about 19% and 22% reductions in global smoking and alcohol consumption, respectively; a 47% decline in adolescent birth rates; and a more than 85% increase in health worker density per 1000 population by 2030. Interpretation: The GBD study offers a unique, robust platform for monitoring the health-related SDGs across demographic and geographic dimensions. Our findings underscore the importance of increased collection and analysis of disaggregated data and highlight where more deliberate design or targeting of interventions could accelerate progress in attaining the SDGs. Current projections show that many health-related SDG indicators, NCDs, NCD-related risks, and violence-related indicators will require a concerted shift away from what might have driven past gains—curative interventions in the case of NCDs—towards multisectoral, prevention-oriented policy action and investments to achieve SDG aims. Notably, several targets, if they are to be met by 2030, demand a pace of progress that no country has achieved in the recent past. The future is fundamentally uncertain, and no model can fully predict what breakthroughs or events might alter the course of the SDGs. What is clear is that our actions—or inaction—today will ultimately dictate how close the world, collectively, can get to leaving no one behind by 2030.
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| 2. |
- Mudgal, Richa, et al.
(författare)
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Magnetic-Proximity-Induced Efficient Charge-to-Spin Conversion in Large-Area PtSe2/Ni80Fe20 Heterostructures
- 2023
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Ingår i: NANO LETTERS. - 1530-6984 .- 1530-6992. ; 23:24, s. 11925-11931
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Tidskriftsartikel (refereegranskat)abstract
- As a topological Dirac semimetal with controllable spin-orbit coupling and conductivity, PtSe2, a transition-metal dichalcogenide, is a promising material for several applications, from optoelectrics to sensors. However, its potential for spintronics applications has yet to be explored. In this work, we demonstrate that the PtSe2/Ni80Fe20 heterostructure can generate large damping-like current-induced spin-orbit torques (SOT), despite the absence of spin-splitting in bulk PtSe2. The efficiency of charge-to-spin conversion is found to be -0.1 +/- 0.02 nm(-1) in PtSe2/Ni80Fe20, which is 3 times that of the control sample, Ni80Fe20/Pt. Our band structure calculations show that the SOT due to PtSe2 arises from an unexpectedly large spin splitting in the interfacial region of PtSe2 introduced by the proximity magnetic field of the Ni80Fe20 layer. Our results open up the possibilities of using large-area PtSe2 for energy-efficient nanoscale devices by utilizing proximity-induced SOT.
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| 3. |
- Kumar, Naresh, et al.
(författare)
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Understanding Antibiotic Usage on Small-Scale Dairy Farms in the Indian States of Assam and Haryana Using a Mixed-Methods Approach—Outcomes and Challenges
- 2021
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Ingår i: Antibiotics. - : MDPI. - 2079-6382. ; 10:9, s. 1124-1124
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Tidskriftsartikel (refereegranskat)abstract
- The use and misuse of antibiotics in both humans and animals contributes to the global emergence of antimicrobial resistant (AMR) bacteria, a threat to public health and infection control. Currently, India is the world’s leading milk producer but antibiotic usage within the dairy sector is poorly regulated. Little data exists reflecting how antibiotics are used on dairy farms, especially on small-scale dairy farms in India. To address this lack of data, a study was carried out on 491 small-scale dairy farms in two Indian states, Assam and Haryana, using a mixed method approach where farmers were interviewed, farms inspected for the presence of antibiotics and milk samples taken to determine antibiotic usage. Usage of antibiotics on farms appeared low only 10% (95% CI 8–13%) of farmers surveyed confirmed using antibiotics in their dairy herds during the last 12 months. Of the farms surveyed, only 8% (6–11%) had milk samples positive for antibiotic residues, namely from the novobiocin, macrolides, and sulphonamide classes of antibiotics. Of the farmers surveyed, only 2% (0.8–3%) had heard of the term “withdrawal period” and 53% (40–65%) failed to describe the term “antibiotic”. While this study clearly highlights a lack of understanding of antibiotics among small-scale dairy farmers, a potential factor in the emergence of AMR bacteria, it also shows that antibiotic usage on these farms is low and that the possible role these farmers play in AMR emergence may be overestimated.
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| 4. |
- Roy, Rupak, et al.
(författare)
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SN 2007uy-metamorphosis of an aspheric Type Ib explosion
- 2013
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Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 434:3, s. 2032-2050
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Tidskriftsartikel (refereegranskat)abstract
- The supernovae (SNe) of Type Ibc are rare and the detailed characteristics of these explosions have been studied only for a few events. Unlike Type II SNe, the progenitors of Type Ibc have never been detected in pre-explosion images. So, to understand the nature of their progenitors and the characteristics of the explosions, investigation of proximate events is necessary. Here we present the results of multiwavelength observations of Type Ib SN 2007uy in the nearby (similar to 29.5 Mpc) galaxy NGC 2770. Analysis of the photometric observations revealed this explosion as an energetic event with peak absolute R-band magnitude -18.5 +/- 0.16, which is about 1 mag brighter than the mean value (-17.6 +/- 0.6) derived for well observed Type Ibc events. The SN is highly extinguished, E(B - V) = 0.63 +/- 0.15 mag, mainly due to foreground material present in the host galaxy. From optical light curve modelling we determine that about 0.3 M-circle dot radioactive Ni-56 is produced and roughly 4.4 M-circle dot material is ejected during this explosion with liberated energy similar to 15 x 10(51) erg, indicating the event to be an energetic one. Through optical spectroscopy, we have noticed a clear aspheric evolution of several line-forming regions, but no dependency of asymmetry is seen on the distribution of Ni-56 inside the ejecta. The SN shock interaction with the circumstellar material is clearly noticeable in radio follow-up, presenting a synchrotron self-absorption dominated light curve with a contribution of free-free absorption during the early phases. Assuming a Wolf-Rayet (WR) star, with wind velocity greater than or similar to 10(3) km s(- 1), as a progenitor, we derive a lower limit to the mass-loss rate inferred from the radio data as M 2.4 10(-5) M-circle dot yr(-1), which is consistent with the results obtained for other Type Ibc SNe bright at radio frequencies.
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| 5. |
- Tewari, Rajni, et al.
(författare)
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The Permian-Triassic palynological transition in the Guryul Ravine section, Kashmir, India: implications for Tethyan – Gondwanan correlations
- 2015
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Ingår i: Earth-Science Reviews. - : Elsevier. - 0012-8252 .- 1872-6828. ; 149, s. 53-66
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Tidskriftsartikel (refereegranskat)abstract
- This first palynological study of the Permian–Triassic succession in the Guryul Ravine, Kashmir, India, reveals impoverished latest Permian spore-pollen assemblages in the uppermost Zewan Formation, a rich palynoassemblage from the basal Khunamuh Formation characteristic of the Permian–Triassic transition zone and depleted Triassic assemblages from higher in the Khunamuh Formation. The collective assemblages can be broadly correlated to the Densipollenites magnicorpus and Klausipollenites decipiens palynozones of peninsular India and to palynofloras spanning the Permian–Triassic boundary elsewhere in Gondwana. Generally, low spore-pollen yields and poor preservational quality of the studied assemblages hinder more precise correlations and are inferred to be a function of an offshore marine depositional setting on the margin of the Neotethys Ocean, and thermal alteration associated with Cenozoic collisional tectonism between India and Asia.
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| 6. |
- Islar, Mine, et al.
(författare)
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Diverse values of nature for sustainability
- 2022
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Ingår i: Nature. - 0028-0836 .- 1476-4687. ; 620, s. 813-823
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Tidskriftsartikel (refereegranskat)abstract
- Twenty-five years since foundational publications on valuing ecosystem services for human well-being1,2, addressing the global biodiversity crisis3 still implies confronting barriers to incorporating nature’s diverse values into decision-making. These barriers include powerful interests supported by current norms and legal rules such as property rights, which determine whose values and which values of nature are acted on. A better understanding of how and why nature is (under)valued is more urgent than ever4. Notwithstanding agreements to incorporate nature’s values into actions, including the Kunming-Montreal Global Biodiversity Framework (GBF)5 and the UN Sustainable Development Goals6, predominant environmental and development policies still prioritize a subset of values, particularly those linked to markets, and ignore other ways people relate to and benefit from nature7. Arguably, a ‘values crisis’ underpins the intertwined crises of biodiversity loss and climate change8, pandemic emergence9 and socio-environmental injustices10. On the basis of more than 50,000 scientific publications, policy documents and Indigenous and local knowledge sources, the Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES) assessed knowledge on nature’s diverse values and valuation methods to gain insights into their role in policymaking and fuller integration into decisions7,11. Applying this evidence, combinations of values-centred approaches are proposed to improve valuation and address barriers to uptake, ultimately leveraging transformative changes towards more just (that is, fair treatment of people and nature, including inter- and intragenerational equity) and sustainable futures.
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| 7. |
- Deswal, Renu, et al.
(författare)
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Plant proteomics in India and Nepal : Current status and challenges ahead
- 2013
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Ingår i: Physiology and Molecular Biology of Plants. - : Springer-Verlag New York. - 0971-5894 .- 0974-0430. ; 19:4, s. 461-477
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Forskningsöversikt (refereegranskat)abstract
- Plant proteomics has made tremendous contributions in understanding the complex processes of plant biology. Here, its current status in India and Nepal is discussed. Gel-based proteomics is predominantly utilized on crops and non-crops to analyze majorly abiotic (49 %) and biotic (18 %) stress, development (11 %) and post-translational modifications (7 %). Rice is the most explored system (36 %) with major focus on abiotic mainly dehydration (36 %) stress. In spite of expensive proteomics setup and scarcity of trained workforce, output in form of publications is encouraging. To boost plant proteomics in India and Nepal, researchers have discussed ground level issues among themselves and with the International Plant Proteomics Organization (INPPO) to act in priority on concerns like food security. Active collaboration may help in translating this knowledge to fruitful applications.
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| 8. |
- Kumar, Dhirender, et al.
(författare)
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Population Dynamics of Juniperus macropoda Bossier Forest Ecosystem in Relation to Soil Physico-Chemical Characteristics in the Cold Desert of North-Western Himalaya
- 2022
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Ingår i: Forests. - : MDPI. - 1999-4907. ; 13:10
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Tidskriftsartikel (refereegranskat)abstract
- Juniperus macropoda is the only tree species of a cold desert ecosystem that is experiencing high anthropogenic pressure and has a poor regeneration status due to harsh environmental conditions. Due to the limited distribution of Juniperus macropoda in this region, the species have remained largely unexplored in terms of understanding the distribution pattern along the elevation and soil fertility gradients. Therefore, the current research was carried out along the elevational gradient, starting from the base line at 3000 m above sea level (m asl) asl with an elevational plot distance of 180 m. The study revealed that the average density of J. macropoda declined gradually from the first elevation range, i.e., 3000–3180 m asl onward, and extended up to the elevation range of 3900–4080 m asl. However, the average seedling and sapling densities were highest at mid-elevation and extended up to an elevation range of 4080–4260 m asl. The J. macropoda population formed a reverse J-shaped structure only up to 3540–3720 m asl. The maximum total biomass and carbon density were recorded in the lowest elevational range, and decreased subsequently. The primary soil nutrients under study decreased sharply along the elevational gradient. Seedling, sapling and tree distributions had a significantly positive relationship (p < 0.05) with available N, P, K, SOC, silt and clay contents and were negatively correlated (p < 0.05) with sand contents. The outcome of the study will form the basis for devising a plan for the management and conservation of J. macropoda forests.
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| 9. |
- Clark, Andrew G., et al.
(författare)
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Evolution of genes and genomes on the Drosophila phylogeny
- 2007
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 450:7167, s. 203-218
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Tidskriftsartikel (refereegranskat)abstract
- Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species.
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| 10. |
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