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Surgical complicati...
Surgical complications and long-term survival after esophagectomy for cancer in a nationwide Swedish cohort study
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- Rutegård, Martin, 1982- (författare)
- Karolinska Institutet
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- Lagergren, P (författare)
- Karolinska Institutet
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- Rouvelas, I (författare)
- Karolinska Institutet
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Mason, R (författare)
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- Lagergren, J (författare)
- Karolinska Institutet
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(creator_code:org_t)
- W.B. Saunders Co. Ltd. 2012
- 2012
- Engelska.
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Ingår i: European Journal of Surgical Oncology. - : W.B. Saunders Co. Ltd.. - 0748-7983 .- 1532-2157. ; 38:7, s. 555-561
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- AIMS: Acute surgical complications after esophageal resection for cancer may decrease the long-term survival. Previous results on this topic are conflicting and no population-based studies are available.METHODS: A prospective, nationwide Swedish study was conducted in 2001-2010. Eligible patients comprised those afflicted by esophageal or cardia cancer and underwent surgical resection in Sweden in 2001-2005. Details concerning patient and tumor characteristics, surgical procedures, and postoperative surgical complications were collected prospectively. Follow-up for mortality, starting from 90 days after the surgery, was done until May 2010. Cox proportional-hazards regression was performed to estimate hazard ratios (HRs) and 95% confidence intervals (CIs), adjusted for age, tumor stage, sex, histology, comorbidity, surgical approach and surgical radicality.RESULTS: Among 567 included patients who survived at least 90 days postoperatively, 130 (22.9%) sustained a predefined surgical complication within 30 days of surgery. The adjusted HR of mortality was increased in patients who sustained surgical complications, compared to patients without such complications (HR 1.29, 95% CI 1.02-1.63).CONCLUSIONS: The occurrence of surgical complications might be an independent predictor for poorer long-term survival in patients resected for esophageal cancer, even in patients who survived the postoperative period.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Esophagus
- Population-based
- Neoplasm
- Surgery
- Mortality
- Leak
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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