Tyck till om SwePub Sök
här!
Search: WFRF:(Landen M)
> (2000-2004)
> (2003)
> Nilsson Staffan 1956 >
Association between...
Association between a dinucleotide repeat polymorphism of the estrogen receptor alpha gene and personality traits in women.
-
- Westberg, Lars, 1973 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi,Institute of Physiology and Pharmacology, Dept of Pharmacology,University of Gothenburg
-
- Melke, Jonas, 1971 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi,Institute of Physiology and Pharmacology, Dept of Pharmacology,University of Gothenburg
-
- Landén, Mikael, 1966 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för klinisk neurovetenskap, Sektionen för psykiatri,Institute of Clinical Neurosciences, Section of Psychiatry,University of Gothenburg
-
show more...
-
- Nilsson, Staffan, 1956 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för matematisk statistik,Department of Mathematical Statistics,University of Gothenburg,Chalmers tekniska högskola,Chalmers University of Technology
-
- Baghaei, Fariba, 1964 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för lungmedicin och allergologi,Institute of Internal Medicine, Dept of Respiratory Medicine/Allergology,University of Gothenburg
-
- Rosmond, Roland, 1966 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för lungmedicin och allergologi,Institute of Internal Medicine, Dept of Respiratory Medicine/Allergology,University of Gothenburg
-
- Jansson, M (author)
- Gothenburg University,Göteborgs universitet,Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi,Institute of Physiology and Pharmacology, Dept of Pharmacology,University of Gothenburg
-
- Holm, Göran, 1942 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för lungmedicin och allergologi,Institute of Internal Medicine, Dept of Respiratory Medicine/Allergology,University of Gothenburg
-
- Björntorp, Per, 1931 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för lungmedicin och allergologi,Institute of Internal Medicine, Dept of Respiratory Medicine/Allergology,University of Gothenburg
-
- Eriksson, Elias, 1956 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi,Institute of Physiology and Pharmacology, Dept of Pharmacology,University of Gothenburg
-
show less...
-
(creator_code:org_t)
- 2003-01-30
- 2003
- English.
-
In: Molecular psychiatry. - : Springer Science and Business Media LLC. - 1359-4184 .- 1476-5578. ; 8:1, s. 118-22
- Related links:
-
https://www.nature.c...
-
show more...
-
http://dx.doi.org/10...
-
https://gup.ub.gu.se...
-
https://doi.org/10.1...
-
https://research.cha...
-
show less...
Abstract
Subject headings
Close
- Estrogens are known to play a key role in the regulation of various aspects of behavior. In order to study the potential contribution of genetic variation in the estrogen receptor (ER) alpha to specific personality traits, we investigated a repeat polymorphism in the ER alpha gene in 172 42-year-old women who had been assessed using the Karolinska Scales of Personality (KSP). Based on the hypothesis that there is a relationship between the length of a repeat polymorphism and gene function,(1) the alleles were divided into two groups: short and long. In order to elucidate the possible influence of the ER alpha gene on the different aspects of personality measured by means of the KSP, the possible association between this gene and four different factors ('neuroticism', 'psychoticism', 'non-conformity', and 'extraversion') was analysed. 'Neuroticism', 'psychoticism', and 'non-conformity' all appeared to be associated with the ER alpha gene. After correction for multiple comparisons by means of permutation analysis, the associations with the factor 'non-conformity'--including the subscales 'indirect aggression' and 'irritability'--and the factor 'psychoticism'--including the subscale 'suspicion'--remained significant. The results suggest that the studied dinucleotide repeat polymorphism of the ER alpha gene may contribute to specific components of personality.
Keyword
- Adult
- Aggression
- physiology
- Anxiety
- genetics
- Dinucleotide Repeats
- Estrogen Receptor alpha
- Female
- Humans
- Irritable Mood
- physiology
- Neurotic Disorders
- genetics
- Personality
- genetics
- Polymorphism
- Genetic
- Receptors
- Estrogen
- genetics
- Polymorphism
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Westberg, Lars, ...
-
Melke, Jonas, 19 ...
-
Landén, Mikael, ...
-
Nilsson, Staffan ...
-
Baghaei, Fariba, ...
-
Rosmond, Roland, ...
-
show more...
-
Jansson, M
-
Holm, Göran, 194 ...
-
Björntorp, Per, ...
-
Eriksson, Elias, ...
-
show less...
- Articles in the publication
-
Molecular psychi ...
- By the university
-
University of Gothenburg
-
Chalmers University of Technology