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| 2. |
- Bengtsson, Magnus, et al.
(författare)
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Fluorescence lidar imaging of fungal growth on high-voltage outdoor composite insulators
- 2005
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Ingår i: Optics and Lasers in Engineering. - : Elsevier BV. - 0143-8166 .- 1873-0302. ; 43:6, s. 624-632
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Tidskriftsartikel (refereegranskat)abstract
- Remote fluorescence imaging of fungal growth on polymeric high-voltage insulators was performed using a mobile lidar system with a laser wavelength of 355 nm. Insulator areas contaminated by fungal growth could be distinguished from clean surfaces and readily be imaged. The experiments were supported by detailed spectral studies performed in laboratory using a fibre-optic fluorosensor incorporating an optical multi-channel analyser system (OMA) and a nitrogen laser emitting radiation at 33 7 nm.
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| 3. |
- Bengtsson, Magnus, et al.
(författare)
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Fungus covered insulator materials studied with laser-induced fluorescence and principal component analysis
- 2005
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Ingår i: Applied Spectroscopy. - : SAGE Publications. - 0003-7028 .- 1943-3530. ; 59:8, s. 1037-1041
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Tidskriftsartikel (refereegranskat)abstract
- A method combining laser-induced fluorescence and principal component analysis to detect and discriminate between algal and fungal growth on insulator materials has been studied. Eight fungal cultures and four insulator materials have been analyzed. Multivariate classifications were utilized to characterize the insulator material, and fungal growth could readily be distinguished from a clean surface. The results of the principal component analyses make it possible to distinguish between algae infected, fungi infected, and clean silicone rubber materials. The experiments were performed in the laboratory using a fiber-optic fluorosensor that consisted of a nitrogen laser and an optical multi-channel analyzer system.
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| 4. |
- Brydegaard, Mikkel, et al.
(författare)
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Short-Wave infrared atmospheric scheimpflug lidar
- 2018
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Ingår i: EPJ Web of Conferences. - : EDP Sciences. ; 176
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Konferensbidrag (refereegranskat)abstract
- Atmospheric dual-band Scheimpflug lidar is demonstrated at 980 and 1550 nm. Signals are compared during three weather conditions, and the spatio-temporal resolution of the atmospheric structure is considered. The potential for aerosol classification is evaluated, and future directions are discussed.
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| 5. |
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| 6. |
- Yan, Hongji, et al.
(författare)
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Synthetic design of growth factor sequestering extracellular matrix mimetic hydrogel for promoting in vivo bone formation
- 2018
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Ingår i: Biomaterials. - : Elsevier. - 0142-9612 .- 1878-5905. ; 161, s. 190-202
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Tidskriftsartikel (refereegranskat)abstract
- Synthetic scaffolds that possess an intrinsic capability to protect and sequester sensitive growth factors is a primary requisite for developing successful tissue engineering strategies. Growth factors such as recombinant human bone morphogenetic protein-2 (rhBMP-2) is highly susceptible to premature degradation and to provide a meaningful clinical outcome require high doses that can cause serious side effects. We discovered a unique strategy to stabilize and sequester rhBMP-2 by enhancing its molecular interactions with hyaluronic acid (HA), an extracellular matrix (ECM) component. We found that by tuning the initial protonation state of carboxylic acid residues of HA in a covalently crosslinked hydrogel modulate BMP-2 release at physiological pH by minimizing the electrostatic repulsion and maximizing the Van der Waals interactions. At neutral pH, BMP-2 release is primarily governed by Fickian diffusion, whereas at acidic pH both diffusion and electrostatic interactions between HA and BMP-2 become important as confirmed by molecular dynamics simulations. Our results were also validated in an in vivo rat ectopic model with rhBMP-2 loaded hydrogels, which demonstrated superior bone formation with acidic hydrogel as compared to the neutral counterpart. We believe this study provides new insight on growth factor stabilization and highlights the therapeutic potential of engineered matrices for rhBMP-2 delivery and may help to curtail the adverse side effects associated with the high dose of the growth factor.
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