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- Shakersain, Behnaz, et al.
(författare)
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Prudent diet may attenuate the adverse effects of Western diet on cognitive decline
- 2016
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Ingår i: Alzheimer's & Dementia. - : Wiley. - 1552-5260 .- 1552-5279. ; 12:2, s. 100-109
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: The influence of mixed dietary patterns on cognitive changes is unknown. Methods: A total of 2223 dementia-free participants aged >= 60 were followed up for 6 years to examine the impact of dietary patterns on cognitive decline. Mini-mental state examination (MMSE) was administered. Diet was assessed by a food frequency questionnaire. By factor analysis, Western and prudent dietary patterns emerged. Mixed-effect models for longitudinal data with repeated measurements were used. Results: Compared with the lowest adherence to each pattern, the highest adherence to prudent pattern was related to less MMSE decline (beta = 0.106, P = .011), whereas the highest adherence to Western pattern was associated with more MMSE decline (beta = -0.156, P < .001). The decline associated withWestern diet was attenuated when accompanied by high adherence to prudent pattern. Discussion: High adherence to prudent diet may diminish the adverse effects of high adherence to Western diet on cognitive decline.
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| 2. |
- Shakersain, Behnaz, et al.
(författare)
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The Nordic Prudent Diet Reduces Risk of Cognitive Decline in the Swedish Older Adults : A Population-Based Cohort Study
- 2018
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Ingår i: Nutrients. - : MDPI AG. - 2072-6643. ; 10:2
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Tidskriftsartikel (refereegranskat)abstract
- Appropriate dietary pattern for preserving cognitive function in northern Europe remains unknown. We aimed to identify a Nordic dietary pattern index associated with slower cognitive decline compared to the Mediterranean-DASH Intervention for Neurodegenerative Delay, Mediterranean Diet, Dietary Approaches to Stop Hypertension, and Baltic Sea Diet indices. A total of 2223 dementia-free adults aged 60 were followed for 6 years. Mini-Mental State Examination was administrated at baseline and follow-ups. Dietary intake was assessed by 98-item food frequency questionnaire, and the Nordic Prudent Dietary Pattern (NPDP) was identified. Data were analysed using mixed-effects and parametric survival models and receiver operating characteristic curves with adjustment for potential confounders. Moderate ( = 0.139, 95% CI 0.077-0.201) and high adherence ( = 0.238, 95% CI 0.175-0.300) to NPDP were associated with less cognitive decline compared to other four indices. High adherence to NPDP was also associated with the lowest risk of MMSE decline to 24 (HR = 0.176, 95% CI 0.080-0.386) and had the greatest ability to predict such decline (area under the curve = 0.70). Moderate-to-high adherence to the NPDP may predict a better-preserved cognitive function among older adults in Nordic countries. Regional dietary habits should be considered in developing dietary guidelines for the prevention of cognitive impairment and dementia.
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