| 1. |
- Andersson, Per, et al.
(författare)
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Anger and disgust shape judgments of social sanctions across cultures, especially in high individual autonomy societies
- 2024
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Ingår i: Scientific Reports. - : Nature Research. - 2045-2322. ; 14:1
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Tidskriftsartikel (refereegranskat)abstract
- When someone violates a social norm, others may think that some sanction would be appropriate. We examine how the experience of emotions like anger and disgust relate to the judged appropriateness of sanctions, in a pre-registered analysis of data from a large-scale study in 56 societies. Across the world, we find that individuals who experience anger and disgust over a norm violation are more likely to endorse confrontation, ostracism and, to a smaller extent, gossip. Moreover, we find that the experience of anger is consistently the strongest predictor of judgments of confrontation, compared to other emotions. Although the link between state-based emotions and judgments may seem universal, its strength varies across countries. Aligned with theoretical predictions, this link is stronger in societies, and among individuals, that place higher value on individual autonomy. Thus, autonomy values may increase the role that emotions play in guiding judgments of social sanctions.
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| 2. |
- Eriksson, Kimmo, et al.
(författare)
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Perceptions of the appropriate response to norm violation in 57 societies
- 2021
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Ingår i: Nature Communications. - : Nature Research. - 2041-1723. ; 12:1
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Tidskriftsartikel (refereegranskat)abstract
- Norm enforcement may be important for resolving conflicts and promoting cooperation. However, little is known about how preferred responses to norm violations vary across cultures and across domains. In a preregistered study of 57 countries (using convenience samples of 22,863 students and non-students), we measured perceptions of the appropriateness of various responses to a violation of a cooperative norm and to atypical social behaviors. Our findings highlight both cultural universals and cultural variation. We find a universal negative relation between appropriateness ratings of norm violations and appropriateness ratings of responses in the form of confrontation, social ostracism and gossip. Moreover, we find the country variation in the appropriateness of sanctions to be consistent across different norm violations but not across different sanctions. Specifically, in those countries where use of physical confrontation and social ostracism is rated as less appropriate, gossip is rated as more appropriate. Little is known about peoples preferred responses to norm violations across countries. Here, in a study of 57 countries, the authors highlight cultural similarities and differences in peoples perception of the appropriateness of norm violations.
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| 3. |
- Petropoulos, Fotios, et al.
(författare)
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Operational Research : methods and applications
- 2024
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Ingår i: Journal of the Operational Research Society. - : Taylor & Francis Group. - 0160-5682 .- 1476-9360. ; 75:3, s. 423-617
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Forskningsöversikt (refereegranskat)abstract
- Throughout its history, Operational Research has evolved to include methods, models and algorithms that have been applied to a wide range of contexts. This encyclopedic article consists of two main sections: methods and applications. The first summarises the up-to-date knowledge and provides an overview of the state-of-the-art methods and key developments in the various subdomains of the field. The second offers a wide-ranging list of areas where Operational Research has been applied. The article is meant to be read in a nonlinear fashion and used as a point of reference by a diverse pool of readers: academics, researchers, students, and practitioners. The entries within the methods and applications sections are presented in alphabetical order. The authors dedicate this paper to the 2023 Turkey/Syria earthquake victims. We sincerely hope that advances in OR will play a role towards minimising the pain and suffering caused by this and future catastrophes.
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| 4. |
- Sun, J L, et al.
(författare)
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Interactions of sequence variants in interieukin-1 receptor-associated kinase4 and the Toll-like receptor 6-1-10 gene cluster increase prostate cancer risk
- 2006
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Ingår i: Cancer Epidemiology, Biomarkers and Prevention. - Wake Forest Univ, Sch Med, Ctr Human Genom, Winston Salem, NC 27109 USA. Wake Forest Univ, Sch Med, Dept Publ Hlth Sci, Winston Salem, NC 27109 USA. Umea Univ, Dept Radiat Sci, Umea, Sweden. Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden. Univ Hosp Uppsala, Reg Oncol Ctr, Uppsala, Sweden. Orebro Univ Hosp, Dept Urol & Clin Med, Orebro, Sweden. Johns Hopkins Med Inst, Dept Urol, Baltimore, MD USA. : AMER ASSOC CANCER RESEARCH. - 1055-9965 .- 1538-7755. ; 15:3, s. 480-485
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Tidskriftsartikel (refereegranskat)abstract
- Chronic or recurrent inflammation has been suggested as a causal factor in several human malignancies, including prostate cancer. Genetic predisposition is also a strong risk factor in the development of prostate cancer. In particular, Toll-like receptors (TLR), especially the TLR6-1-10 gene cluster, are involved in prostate cancer development. Interleukin-1 receptor-associated kinases (IRAK) 1 and 4 are critical components in the TLR signaling pathway. In this large case-control study, we tested two hypotheses: (a) sequence variants in IRAK1 and IRAK4 are associated with prostate cancer risk and (b) sequence variants in IRAK1/4 and TLR1-6-10 interacts and confers a stronger risk to prostate cancer. We analyzed 11 single nucleotide polymorphisms (four in IRAK1 and seven in IRAK4) among 1,383 newly diagnosed prostate cancer patients and 780 population controls in Sweden. Although the single-nucleotide polymorphisms in IRAK1 and IRAK4 alone were not significantly associated with prostate cancer risk, one single-nucleotide polymorphism in IRAK4, when combined with the high-risk genotype at TLR6-1-10, conferred a significant excess risk of prostate cancer. In particular, men with the risk genotype at TLR6-1-10 and IRAK4-7987 CG/CC had an odds ratio of 9.68 (P = 0.03) when compared with men who had wildtype genotypes. Our findings suggest synergistic effects between sequence variants in IRAK4 and the TLR 6-1-10 gene cluster. Although this study was based on a priori hypothesis and was designed to address many common issues facing this type of study, our results need confirmation in even larger studies.
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| 5. |
- Duggan, D., et al.
(författare)
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Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP
- 2007
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Ingår i: Journal of the National Cancer Institute. - : Oxford University Press (OUP). - 0027-8874 .- 1460-2105. ; 99:24, s. 1836-1844
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Tidskriftsartikel (refereegranskat)abstract
- Background: The consistent finding of a genetic susceptibility to prostate cancer suggests that there are germline sequence variants predisposing individuals to this disease. These variants could be useful in screening and treatment. Methods: We performed an exploratory genome-wide association scan in 498 men with aggressive prostate cancer and 494 control subjects selected from a population-based case-control study in Sweden. We combined the results of this scan with those for aggressive prostate cancer from the publicly available Cancer Genetic Markers of Susceptibility (CGEMS) Study. Single-nucleotide polymorphisms (SNPs) that showed statistically significant associations with the risk of aggressive prostate cancer based on two-sided allele tests were tested for their association with aggressive prostate cancer in two independent study populations composed of individuals of European or African American descent using one-sided tests and the genetic model (dominant or additive) associated with the lowest value in the exploratory study. Results: Among the approximately 60000 SNPs that were common to our study and CGEMS, we identified seven that had a similar (positive or negative) and statistically significant (P<.01) association with the risk of aggressive prostate cancer in both studies. Analysis of the distribution of these SNPs among 1032 prostate cancer patients and 571 control subjects of European descent indicated that one, rs1571801, located in the DAB2IP gene, which encodes a novel Ras GTPase-activating protein and putative prostate tumor suppressor, was associated with aggressive prostate cancer (one-sided P value =. 004). The association was also statistically significant in an African American study population that included 210 prostate cancer patients and 346 control subjects (one-sided P value =. 02). Conclusion: A genetic variant in DAB2IP may be associated with the risk of aggressive prostate cancer and should be evaluated further.
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| 6. |
- Li, Y., et al.
(författare)
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Study on the optimal deployment for Photovoltaic components recycle in China
- 2019
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Ingår i: Energy Procedia. - : Elsevier Ltd. - 1876-6102. ; , s. 4298-4303
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Konferensbidrag (refereegranskat)abstract
- Photovoltaic (PV) production and installation surge in recent years because of technology development and policy orientation. However, due the deadlines of subsidy set by Chinese government, most of the PV projects are carried out in a hurry and quality issues appear. Some equipment turn out to be inferiors. The demand for subsequent treatment for PV components will surge in the early future. However, the insufficiency of recycle facilities and supporting policies, lack of public focus, make it difficult. For a better planning of PV recycle, an optimization model is applied to study on the optimal deployment of PV recycle centers in China during 2040 to 2045 based on cost minimization. Transportation cost for PV modules, capital cost and operational cost for recycle center in different provinces are taken into consideration of objective functions. The result indicates that the peak of PV components recycle will arrive around 2042. At the early stage, recycle centers will be established in Zhejiang, Guangdong, and Shanxi province, considering the intensive installation and convenient transportation. The discarded PV panels will be transported to those provinces. Then, as the recycle demand surging, recycle centers will be scattered in many provinces, such as Jiangsu, Ningxia, Hebei, Inner Mongolia and so on. Most of the PV components will be recycled within the installed provinces.
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| 7. |
- Shen, B., et al.
(författare)
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The role of regulatory reforms, market changes, and technology development to make demand response a viable resource in meeting energy challenges
- 2014
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Ingår i: Applied Energy. - : Elsevier BV. - 0306-2619. ; 130, s. 814-823
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Tidskriftsartikel (refereegranskat)abstract
- In recent years, demand response and load control automation has gained increased attention from regulators, system operators, utilities, market aggregators, and product vendors. It has become a cost-effective demand-side alternative to traditional supply-side generation technologies to balance the power grid, enable grid integration of renewable energy, and meet growing demands for electricity. There are several factors that have played a role in the development of demand response programs. Existing research are however limited on reviewing in a systematic approach how these factors work together to drive this development. This paper makes an attempt to fill this gap. It provides a comprehensive overview on how policy and regulations, electricity market reform, and technological advancement in the US and other countries have worked for demand response to become a viable demand-side resource to address the energy and environmental challenges. The paper also offers specific recommendations on actions needed to capture untapped demand response potentials in countries that have developed active demand response programs as well as countries that plan to pursue demand response.
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| 8. |
- Sun, J L, et al.
(författare)
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Sequence variants in toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk
- 2005
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Ingår i: Journal of the National Cancer Institute. - Wake Forest Univ, Sch Med, Ctr Human Genom, Winston Salem, NC 27157 USA. Umea Univ, Dept Radiat Sci & Oncol, Umea, Sweden. Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden. Orebro Univ Hosp, Dept Urol & Clin Med, Orebro, Sweden. Univ Uppsala Hosp, Reg Oncol Ctr, Uppsala, Sweden. Johns Hopkins Sch Med, Dept Urol, Baltimore, MD USA. : OXFORD UNIV PRESS INC. - 0027-8874 .- 1460-2105. ; 97:7, s. 525-532
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Tidskriftsartikel (refereegranskat)abstract
- Background: Chronic inflammation plays an important role in several human cancers and may be involved in the etiology of prostate cancer. Toll-like receptors (TLRs) are important in the innate immune response to pathogens and in cross-talk between innate immunity and adaptive immunity. Our previous finding of an association of TLR4 gene sequence variants and prostate cancer risk provides evidence for a role of TLRs in prostate cancer. In this study, we investigated whether sequence variants in the TLR6-TLR1-TLR10 gene cluster, residing within a 54-kb region on 4p14, were associated with prostate cancer risk. Methods: We selected 32 single-nucleotide polymorphisms (SNPs) covering these three genes and genotyped these SNPs in 96 control subjects from the Cancer Prostate in Sweden (CAPS) population-based prostate cancer case-control study. Five distinct haplotype blocks were inferred at this region, and we identified 17 haplotype-tagging SNPs (htSNPs) that could uniquely describe < 95% of the haplotypes. These 17 htSNPs were then genotyped in the entire CAPS study population (1383 case subjects and 780 control subjects). Odds ratios of prostate cancer for the carriers of a variant allele versus those with the wild-type allele were estimated using unconditional logistic regression. Results: The allele frequencies of 11 of the 17 SNPs were statistically significantly different between case and control subjects (P = .04-.001), with odds ratios for variant allele carriers (homozygous or heterozygous) compared with wild-type allele carriers ranging from 1.20 (95% confidence interval [CI] = 1.00 to 1.43) to 1.38 (95% CI = 1.12 to 1.70). Phylogenetic tree analyses of common haplotypes identified a clade of two evolutionarily related haplotypes that are statistically significantly associated with prostate cancer risk. These two haplotypes contain all the risk alleles of these 11 associated SNPs. Conclusion: The observed multiple associated SNPs at the TLR6-TLR1-TLR10 gene cluster were dependent and suggest the presence of a founder prostate cancer risk variant on this haplotype background. The TLR6-TLR1-TLR10 gene cluster may play a role in prostate cancer risk, although further functional studies are needed to pinpoint the disease-associated variants in this gene cluster.
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| 9. |
- Tian, Ruijie, et al.
(författare)
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Study on the promotion of natural gas-fired electricity with energy market reform in China using a dynamic game-theoretic model
- 2017
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Ingår i: Applied Energy. - : Elsevier BV. - 0306-2619 .- 1872-9118. ; 185, s. 1832-1839
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Tidskriftsartikel (refereegranskat)abstract
- Natural gas-fired electricity (NGFE) has gained great attention in China recently. However, the high generation cost leads to the NGFE cannot compete economically with the coal-fired electricity (CFE) when the value of peak power and positive environment externality of NGEF are not considered. Therefore, the market reform of natural gas (NG), including price deregulation, carbon tax and environmental subsidy are of vital importance to promote the penetration of NGFE. In the present study, a dynamic game-theoretic model was developed to analyze the impacts of market reforming for natural gas on the promotion effect of NGFE, in which the hourly real-time pricing (RTP) was applied in both natural gas and electricity markets. Five scenarios were proposed with different policy combinations of pricing mechanism reform, carbon tax and environmental subsidy. Based on the analysis results, it can be concluded that (i) deregulating the NG price, imposing carbon tax and adopting environment subsidy can promote the market penetration of NGFE greatly; and (ii) the market deregulation can increases the share of NGFE to 5.49%, and imposing the carbon tax of 100RMB/tonne CO2 can raise it further to 7.66%, furthermore if the environmental subsidy of 134.3 RMB/MWh is also included, the share of NGFE can reach 15%.
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| 10. |
- Wang, G., et al.
(författare)
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Policy simulation for promoting residential PV considering anecdotal information exchanges based on social network modelling
- 2018
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Ingår i: Applied Energy. - : Elsevier Ltd. - 0306-2619 .- 1872-9118. ; 223, s. 1-10
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Tidskriftsartikel (refereegranskat)abstract
- Surveys and empirical researches have revealed that the households’ perceptions of benefits play a more important role than the benefits themselves in the decision process of adopting residential photovoltaic (PV). However, it has been overlooked in previous models about the green technology diffusion. This work developed an innovation diffusion model based on a social network, which was integrated with an anecdotal information exchange process. The contributions were to model the households’ evaluation, which changes with social influence, and analyze the impact of such dynamics on the adoption of residential PV. A case study was conducted for villages in Beijing. Different scenarios about policies have been considered concerning both the economic benefits and the information diffusion on social network. The results show that: (1) Providing insurance against the damage of PV to adopters for free can improve the adoption rate from 24% up to 62% (full insurance), and the new adopter acquisition cost is only 36% of that of providing additional subsidy; (2) The enhancement of communications (e.g. Bulletin Board System (BBS) and Social Networking Services (SNS)) creates an obstacle to the residential PV adoption when the majority of households have insufficient knowledge about the PV system; and (3) Information campaigns and information screening are both effective and necessary in mitigating the negative effect from the enhancement of communications at the initial stage of the residential PV market.
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