| 1. |
- Jacobson, Petra, et al.
(författare)
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Applying the Rome Proposal on Exacerbations of Chronic Obstructive Pulmonary Disease : Does Comorbid Chronic Heart Failure Matter?
- 2023
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Ingår i: The International Journal of Chronic Obstructive Pulmonary Disease. - : Dove Medical Press Ltd. - 1176-9106 .- 1178-2005. ; 18, s. 2055-2064
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Tidskriftsartikel (refereegranskat)abstract
- Background: Chronic heart failure (CHF) is a common comorbidity among patients with chronic obstructive pulmonary disease (COPD). Both exacerbations of COPD (ECOPDs) and exacerbations of CHF (ECHFs) display worsening of breathlessness at rest (BaR) and breathlessness at physical activity (BaPA). Comorbid CHF may have an impact on the vital signs assessed, when the Rome proposal (adopted by GOLD 2023) is applied on ECOPDs. Thus, the aim of the present study was to investigate the impact of comorbid CHF on ECOPDs severity, particularly focusing on the influence of comorbid CHF on BaR and BaPA. Methods: We analysed data on COPD symptoms collected from the telehealth study The eHealth Diary. Patients with COPD (n = 43) and patients with CHF (n = 41) were asked to daily monitor BaR and BaPA, employing a digital pen and scales for BaR and BaPA (from 0 to 10). Twenty-eight patients of the COPD patients presented with comorbid CHF. Totally, 125 exacerbations were analysed. Results: Exacerbations in the group with COPD patients and comorbid CHF were compared to the group with COPD patients without comorbid CHF and the group with CHF patients. Compared with GOLD 2022, the GOLD 2023 (the Rome proposal) significantly downgraded the ECOPD severity. Comorbid CHF did not interfere significantly on the observed difference. Comorbid CHF did not worsen BaR scores, assessed at inclusion and at the symptom peak of the exacerbations. Conclusion: In the present study, we find no evidence that comorbid CHF would interfere significantly with the parameters included in the Rome proposal (GOLD 2023). We conclude that the Rome proposal can be safely applied even on COPD patients with very advanced comorbid CHF.
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| 2. |
- Zhou, R., et al.
(författare)
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Maritime Disruption Impact Evaluation Using Simulation and Big Data Analytics
- 2022
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Ingår i: Proceedings - Winter Simulation Conference. - : Institute of Electrical and Electronics Engineers Inc.. - 9798350309713 ; , s. 784-795
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Konferensbidrag (refereegranskat)abstract
- Disruptions in maritime networks may cause significant financial burden and damage to business. Recently, some international ports have been experiencing unprecedented congestions due to the COVID19 pandemic and other disruptions. It is paramount for the maritime industry to further enhance the capability to assess and predict impacts of disruptions. With more data available from industrial digitization and more advanced technologies developed for big data analytics and simulation, it is possible to build up such capability. In this study, we developed a discrete event simulation model backed with big data analytics for realistic and valid inputs to assess impacts of the Suez Canal blockage to the Port of Singapore. The simulation results reveal an interesting finding that, the blockage occurred in the Suez Canal can hardly cause significant congestion in the Port of Singapore. The work can be extended to evaluate impacts of other types of disruptions, even occurring concurrently.
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