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Träfflista för sökning "WFRF:(Lindberg B) "

Search: WFRF:(Lindberg B)

  • Result 1-10 of 628
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  • 2017
  • swepub:Mat__t
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  • Campbell, PJ, et al. (author)
  • Pan-cancer analysis of whole genomes
  • 2020
  • In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 578:7793, s. 82-
  • Journal article (peer-reviewed)abstract
    • Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1–3. Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4–5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter4; identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation5,6; analyses timings and patterns of tumour evolution7; describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity8,9; and evaluates a range of more-specialized features of cancer genomes8,10–18.
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  • Audouin, L., et al. (author)
  • High-precision measurement of isotopic fission yields of 236 U
  • 2018
  • In: EPJ Web of Conferences. - : EDP Sciences. - 2101-6275 .- 2100-014X. ; 193
  • Conference paper (peer-reviewed)abstract
    • We report on the second SOFIA experiment, dedicated to the fission yields of 236U∗, analog to 235U(n,f). The measurement is based on the inverse kinematics method, using a relativistic, secondary beam of 236U. Both fission fragments are identified in mass and charge in the SOFIA recoil spectrometer. The obtained isotopic yields are compared with existing spectroscopy measurements and the elemental yields are used to discuss the treatment of the even-odd effect with energy in nuclear data libraries.
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  • Chatillon, A., et al. (author)
  • Accurate measurements of fission-fragment yields in U-234,U-235,U-236,U-238(gamma,f) with the SOFIA set-up
  • 2016
  • In: EPJ Web of Conferences. - : EDP Sciences. - 2101-6275 .- 2100-014X. - 9782759819706 ; 111
  • Conference paper (peer-reviewed)abstract
    • SOFIA (Studies On Fission with Aladin) is a new experimental set-up dedicated to accurate measurement of fission-fragments isotopic yields. It is located at GSI, the only place to use inverse kinematics at relativistic energies in order to study the (gamma,f) electromagnetic-induced fission. The SOFIA set-up is a large-acceptance magnetic spectrometer, which allows to fully identify both fission fragments in coincidence on the whole fission-fragment range. This paper will report on fission yields obtained in U-234,U-235,U-236,U-238(gamma,f) reactions.
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  • Result 1-10 of 628
Type of publication
journal article (462)
conference paper (131)
other publication (18)
book chapter (5)
reports (4)
research review (3)
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book (2)
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Type of content
peer-reviewed (438)
other academic/artistic (188)
pop. science, debate, etc. (1)
Author/Editor
Hellstrom-Lindberg, ... (81)
LINDBERG, B (59)
Lindberg, J (40)
Lindberg, A (38)
Lindberg, G (32)
Lindberg, K (29)
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Lindberg, Eva (26)
Zhivotovsky, B (20)
Gronberg, H (20)
Lindberg, P (18)
Christensson, B (17)
Gislason, T. (17)
Lindberg, AA (16)
Lindberg, M (16)
Scott, B (16)
Lindberg, Staffan I. ... (16)
Andersson, G (15)
Karimi, M (15)
Benediktsdottir, B. (15)
Fadeel, B (15)
Yucel-Lindberg, T (15)
Janson, Christer (14)
Tobiasson, M (12)
Rossi, D (12)
Real, F. G. (12)
Schlunssen, V. (12)
Lindberg, Fredrik, 1 ... (12)
Melin, L (12)
Jansson, M. (11)
Nilsson, L. (11)
Heinz, Andreas Marti ... (11)
Simon, H (11)
Pauly, C. (11)
Bashkanov, M. (11)
Clement, H. (11)
Petukhov, Y. (11)
Skorodko, T. (11)
Stepaniak, J. (11)
Zabierowski, J. (11)
Scobel, W (11)
Lindberg, L (11)
Lindberg, E (11)
Morosov, B. (11)
Tikhomirov, V. (11)
Lundback, B (11)
Gerén, L. (11)
Bargholtz, Chr (11)
Lindberg, Simon, 198 ... (11)
Ivanov, G. (11)
Jiganov, E. (11)
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Karolinska Institutet (324)
Uppsala University (128)
University of Gothenburg (94)
Lund University (78)
Umeå University (53)
Royal Institute of Technology (21)
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Stockholm University (21)
Chalmers University of Technology (18)
Linköping University (13)
Linnaeus University (10)
Örebro University (9)
University of Gävle (7)
Luleå University of Technology (4)
RISE (4)
Swedish University of Agricultural Sciences (4)
Malmö University (3)
University of Skövde (2)
Karlstad University (2)
Kristianstad University College (1)
University West (1)
Jönköping University (1)
Högskolan Dalarna (1)
Swedish Museum of Natural History (1)
Blekinge Institute of Technology (1)
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Language
English (619)
Swedish (9)
Research subject (UKÄ/SCB)
Medical and Health Sciences (146)
Natural sciences (66)
Social Sciences (33)
Engineering and Technology (16)
Agricultural Sciences (2)

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