| 1. |
- Aad, G, et al.
(författare)
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- 2015
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swepub:Mat__t
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| 2. |
- Schael, S., et al.
(författare)
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Electroweak measurements in electron positron collisions at W-boson-pair energies at LEP
- 2013
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Ingår i: Physics Reports. - : Elsevier BV. - 0370-1573 .- 1873-6270. ; 532:4, s. 119-244
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Forskningsöversikt (refereegranskat)abstract
- Electroweak measurements performed with data taken at the electron positron collider LEP at CERN from 1995 to 2000 are reported. The combined data set considered in this report corresponds to a total luminosity of about 3 fb(-1) collected by the four LEP experiments ALEPH, DELPHI, 13 and OPAL, at centre-of-mass energies ranging from 130 GeV to 209 GeV. Combining the published results of the four LEP experiments, the measurements include total and differential cross-sections in photon-pair, fermion-pair and four-fermion production, the latter resulting from both double-resonant WW and ZZ production as well as singly resonant production. Total and differential cross-sections are measured precisely, providing a stringent test of the Standard Model at centre-of-mass energies never explored before in electron positron collisions. Final-state interaction effects in four-fermion production, such as those arising from colour reconnection and Bose Einstein correlations between the two W decay systems arising in WW production, are searched for and upper limits on the strength of possible effects are obtained. The data are used to determine fundamental properties of the W boson and the electroweak theory. Among others, the mass and width of the W boson, m(w) and Gamma(w), the branching fraction of W decays to hadrons, B(W -> had), and the trilinear gauge-boson self-couplings g(1)(Z), K-gamma and lambda(gamma), are determined to be: m(w) = 80.376 +/- 0.033 GeV Gamma(w) = 2.195 +/- 0.083 GeV B(W -> had) = 67.41 +/- 0.27% g(1)(Z) = 0.984(-0.020)(+0.018) K-gamma - 0.982 +/- 0.042 lambda(gamma) = 0.022 +/- 0.019. (C) 2013 Elsevier B.V. All rights reserved.
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| 3. |
- Schael, S, et al.
(författare)
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Precision electroweak measurements on the Z resonance
- 2006
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Ingår i: Physics Reports. - : Elsevier BV. - 0370-1573 .- 1873-6270. ; 427:5-6, s. 257-454
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Forskningsöversikt (refereegranskat)abstract
- We report on the final electroweak measurements performed with data taken at the Z resonance by the experiments operating at the electron-positron colliders SLC and LEP. The data consist of 17 million Z decays accumulated by the ALEPH, DELPHI, L3 and OPAL experiments at LEP, and 600 thousand Z decays by the SLID experiment using a polarised beam at SLC. The measurements include cross-sections, forward-backward asymmetries and polarised asymmetries. The mass and width of the Z boson, m(Z) and Gamma(Z), and its couplings to fermions, for example the p parameter and the effective electroweak mixing angle for leptons, are precisely measured: m(Z) = 91.1875 +/- 0.0021 GeV, Gamma(Z) = 2.4952 +/- 0.0023 GeV, rho(l) = 1.0050 +/- 0.0010, sin(2)theta(eff)(lept) = 0.23153 +/- 0.00016. The number of light neutrino species is determined to be 2.9840 +/- 0.0082, in agreement with the three observed generations of fundamental fermions. The results are compared to the predictions of the Standard Model (SM). At the Z-pole, electroweak radiative corrections beyond the running of the QED and QCD coupling constants are observed with a significance of five standard deviations, and in agreement with the Standard Model. Of the many Z-pole measurements, the forward-backward asymmetry in b-quark production shows the largest difference with respect to its SM expectation, at the level of 2.8 standard deviations. Through radiative corrections evaluated in the framework of the Standard Model, the Z-pole data are also used to predict the mass of the top quark, m(t) = 173(+10)(+13) GeV, and the mass of the W boson, m(W) = 80.363 +/- 0.032 GeV. These indirect constraints are compared to the direct measurements, providing a stringent test of the SM. Using in addition the direct measurements of m(t) and m(W), the mass of the as yet unobserved SM Higgs boson is predicted with a relative uncertainty of about 50% and found to be less than 285 GeV at 95% confidence level. (c) 2006 Elsevier B.V. All rights reserved.
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| 4. |
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- 2019
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Tidskriftsartikel (refereegranskat)
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| 5. |
- Georgieva, Iskra, 1987, et al.
(författare)
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Hot planets around cool stars - two short-period mini-Neptunes transiting the late K-dwarf TOI-1260
- 2021
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Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 505:4, s. 4684-4701
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Tidskriftsartikel (refereegranskat)abstract
- We present the discovery and characterization of two sub-Neptunes in close orbits, as well as a tentative outer planet of a similar size, orbiting TOI-1260 - a low metallicity K6V dwarf star. Photometry from Transiting Exoplanet Survey Satellite(TESS) yields radii of R-b = 2.33 +/- 0.10 and R-c = 2.82 +/- 0.15 R-circle plus, and periods of 3.13 and 7.49 d for TOI-1260b and TOI-1260c, respectively. We combined the TESS data with a series of ground-based follow-up observations to characterize the planetary system. From HARPS-N high-precision radial velocities we obtain M-b = and M-c = M-circle plus. The star is moderately active with a complex activity pattern, which necessitated the use of Gaussian process regression for both the light-curve detrending and the radial velocity modelling, in the latter case guided by suitable activity indicators. We successfully disentangle the stellar-induced signal from the planetary signals, underlining the importance and usefulness of the Gaussian process approach. We test the system's stability against atmospheric photoevaporation and find that the TOI-1260 planets are classic examples of the structure and composition ambiguity typical for the 2-3 R-circle plus range.
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| 6. |
- Brenner, Richard, et al.
(författare)
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Multi Gigabit Wireless Data Transfer in Detectors at Future Colliders
- 2022
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Ingår i: Frontiers in Physics. - : Frontiers Media S.A.. - 2296-424X. ; 10
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Forskningsöversikt (refereegranskat)abstract
- The WADAPT (Wireless Allowing Data And Power Transmission) consortium has been formed to identify the specific needs of different projects that might benefit from wireless communication technologies with the objective of providing a common platform for research and development in order to optimize effectiveness and cost. Wireless technologies have developed extremely fast over the last decade and are now mature enough to be a promising alternative to cables and optical links, with a possibility of revolutionizing detector design. Although wireless readout has the qualities and properties to be used in many collider detectors, this article focuses on the transmission of large amount of data from vertex detectors at high rate, low power budget and in potential high radiation environment. For vertex detectors, the 60 GHz band has proven to be adequate and commercial products are already available, providing 6 Gbps data links. This technology allows efficient partitioning of detectors in topological regions of interest, with the possibility of adding intelligence on the detector to perform four-dimensional reconstruction of the tracks and vertices online, in order to attach the tracks to their vertex with great efficiency even in difficult experimental conditions, and conveniently substitutes a mass of materials (cables and connectors). Early transceiver module products have been successfully tested for signal confinement, crosstalk, electromagnetic immunity and resistance to radiation. In the long run, emerging 140 GHz bands could also be used for higher data rates (>100 Gbps) at future high energy and luminosity hadron colliders.
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| 7. |
- Desidera, S., et al.
(författare)
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TOI-179 : A young system with a transiting compact Neptune-mass planet and a low-mass companion in outer orbit
- 2023
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 675
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Tidskriftsartikel (refereegranskat)abstract
- Context. Transiting planets around young stars are key benchmarks for our understanding of planetary systems. One such candidate, TOI-179, was identified around the K dwarf HD 18599 by TESS.Aims. We present the confirmation of the transiting planet and the characterization of the host star and of the TOI-179 system over a broad range of angular separations.Methods. We exploited the TESS photometric time series, intensive radial velocity monitoring performed with HARPS, and deep high-contrast imaging observations obtained with SPHERE and NACO at VLT. The inclusion of Gaussian process regression analysis was effective to properly model the magnetic activity of the star and identify the Keplerian signature of the transiting planet.Results. The star, with an age of 400 & PLUSMN;100 Myr, is orbited by a transiting planet with period 4.137436 days, mass 24 & PLUSMN;7 M-& OPLUS;, radius 2.62(-0.12)(+0.15) R-& OPLUS;, and significant eccentricity (0.34(-0.09)(+0.07)). Adaptive optics observations identified a low-mass companion at the boundary between brown dwarfs and very low-mass stars (mass derived from luminosity 83(-6)(+4) M-J) at a very small projected separation (84.5 mas, 3.3 au at the distance of the star). Coupling the imaging detection with the long-term radial velocity trend and the astrometric signature, we constrained the orbit of the low-mass companion, identifying two families of possible orbital solutions.Conclusions. The TOI-179 system represents a high-merit laboratory for our understanding of the physical evolution of planets and other low-mass objects and of how the planet properties are influenced by dynamical effects and interactions with the parent star.
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| 8. |
- Lopergolo, D., et al.
(författare)
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Familial Alzheimer's disease associated with heterozygous NPC1 mutation
- 2023
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Ingår i: Journal of medical genetics. - 0022-2593.
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Tidskriftsartikel (refereegranskat)abstract
- Introduction NPC1 mutations are responsible for Niemann-Pick disease type C (NPC), a rare autosomal recessive neurodegenerative disease. Patients harbouring heterozygous NPC1 mutations may rarely show parkinsonism or dementia. Here, we describe for the first time a large family with an apparently autosomal dominant late-onset Alzheimer's disease (AD) harbouring a novel heterozygous NPC1 mutation.Methods All the five living siblings belonging to the family were evaluated. We performed clinical evaluation, neuropsychological tests, assessment of cerebrospinal fluid markers of amyloid deposition, tau pathology and neurodegeneration (ATN), structural neuroimaging and brain amyloid-positron emission tomography. Oxysterol serum levels were also tested. A wide next-generation sequencing panel of genes associated with neurodegenerative diseases and a whole exome sequencing analysis were performed.Results We detected the novel heterozygous c.3034G>T (p.Gly1012Cys) mutation in NPC1, shared by all the siblings. No other point mutations or deletions in NPC1 or NPC2 were found. In four siblings, a diagnosis of late-onset AD was defined according to clinical characterisation and ATN biomarkers (A+, T+, N+) and serum oxysterol analysis showed increased 7-ketocholesterol and cholestane-3 beta,5 alpha,6 beta-triol.Discussion We describe a novel NPC1 heterozygous mutation harboured by different members of a family with autosomal dominant late-onset amnesic AD without NPC-associated features. A missense mutation in homozygous state in the same aminoacidic position has been previously reported in a patient with NPC with severe phenotype. The alteration of serum oxysterols in our family corroborates the pathogenic role of our NPC1 mutation. Our work, illustrating clinical and biochemical disease hallmarks associated with NPC1 heterozygosity in patients affected by AD, provides relevant insights into the pathogenetic mechanisms underlying this possible novel association.
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| 9. |
- Nemolato, S., et al.
(författare)
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Immunoreactivity for thymosin beta 4 and thymosin beta 10 in the adult rat oro-gastrointestinal tract
- 2013
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Ingår i: European Journal of Histochemistry. - : PAGEPress Publications. - 1121-760X .- 2038-8306. ; 57:2, s. 106-111
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Tidskriftsartikel (refereegranskat)abstract
- Thymosin beta 4 (T beta 4) and thymosin beta 10 (T beta 10) are two members of the beta-thymosin family, involved in multiple cellular activities in different organs in multiple animal species. Here we report the expression pattern of T beta 4 and T beta 10 in rat tissues, in the gut and in annexed glands. The two peptide were differently expressed: T beta 4 was absent in salivary glands whereas T beta 10 was expressed in parotid and in submandibular glands. T beta 4 was mildly expressed in the tongue and in the oesophagus, where T beta 10 was absent. A similar expression was found in the stomach, ileum and colon mucosa. In pancreas T beta 4 reactivity was restricted to the Langerhans islet cells; T beta 4 was also detected in the exocrine cells. Both peptide were not expressed in liver cells. When the rat expression pattern in rat organs was compared to reactivity for T beta 4 and T beta 10 in humans, marked differences were found. Our data clearly indicate a species-specific expression of T beta 4 and T beta 10, characterized by the actual unpredictability of the expression of these peptides in different cells and tissues. The common high expression of T beta 4 in mast cells, both in humans and in rats, represents one of the few similarities between these two species.
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| 10. |
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