| 1. |
- Ademark, Pia, et al.
(author)
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Hydrolytic properties of a beta-mannosidase purified from Aspergillus niger. J. Biotechnol. 75: 281-289.
- 1999
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In: Journal of Biotechnology. - 1873-4863. ; 75:2-3, s. 281-289
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Journal article (peer-reviewed)abstract
- A β-mannosidase was purified to homogeneity from the culture filtrate of Aspergillus niger. A specific activity of 500 nkat mg−1 and a 53-fold purification was achieved using ammonium sulfate precipitation, anion-exchange chromatography, and gel filtration. The isolated enzyme has an isoelectric point of 5.0 and appears to be a dimer composed of two 135-kDa subunits. It is a glycoprotein and contains 17% N-linked carbohydrate by weight. Maximal activity was observed at pH 2.4–5.0 and at 70°C. The β-mannosidase hydrolyzed β-1,4-linked manno-oligosaccharides of degree of polymerization (DP) 2–6 and also released mannose from polymeric ivory nut mannan and galactomannan. The Km and Vmax values for p-nitrophenyl-β-Image-mannopyranoside were 0.30 mM and 500 nkat mg−1, respectively. Hydrolysis of Image-galactose substituted manno-oligosaccharides showed that the β-mannosidase was able to cleave up to, but not beyond, a side group. An internal peptide sequence of 15 amino acids was highly similar to that of an Aspergillus aculeatus β-mannosidase belonging to family 2 of glycosyl hydrolases.
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| 2. |
- Ahlberger, Christer, 1956, et al.
(author)
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Consumption fantasies in Modern Literature 1820-1860. The making of the modern consumer
- 2010
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In: ESSHC 2010 – Material and Consumer Culture /MAT03: Homemaking, Cherishing and the Senses.
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Conference paper (peer-reviewed)abstract
- During the first half of the 19th century Sweden was undergoing a rapid integration with the capitalistic world economy. A fundamental part if this process was a profound change of consumption patterns among ordinary people. This change is the focus of our research project. Earlier research has focused on describing and explaining the concrete changes in consumption during this period. Today we have a reasonably good knowledge of the use of new commodities like colonial goods and textiles among different social groups and the sexes. On the other hand we still have little understanding of the context of the consumption. The methods and sources hitherto used in historical studies of emerging and changing consumption patterns simply do not allow us to fully analyse and interpret the attitudes and circumstances of the use of specific consumer items. Our research project takes as its point of departure a notion first conceived by the sociologist Werner Sombart and later developed by the historian Collin Campbell. Campbell claims in The romantic ethic and the Spirit of Modern Consumerism that the origins of the consumer society should be sought in the dreams for new commodities and the desire of satisfaction by the use of new commodities. The purchase creates however disappointment and frustration, since reality does not correspond to the hopes pinned in advance. From this frustration new needs and consumption fantasies are born. The aim of this project is to investigate how these consumption fantasies were created and what they consisted of. The British historian Maxine Berg stresses in Luxury and pleasure in eighteenth-century Britain the connection between our senses and modern consumption. She says that the ”representations of fashion are typically sexualized”. She quotes Sombart who claims that “sensuous pleasure and erotic pleasure are essentially the same”. When capitalism and industrialization extended the opportunities for consumption to the lower classes, this resulted in an obsession for fashion and luxury, a “sensual arousal”. Therefore you can say, that in the first half of the nineteenth century, along with the agrarian, the demographic and the industrial revolutions, Sweden experienced – along with other western countries – a sensual revolution. There is an extremely rich and currently underutilized source for understanding and analyzing the modern consumption society in contemporary literature. Nancy Armstrong, professor in literature, has shown in her study Desire and domestic fiction: a political history of the novel the great impact of the modern novel in 19th century England. Studies of Swedish contemporary literature, has convinced us that it can be used as a historical source. Hence our project has two specific goals: Firstly to deepen the understanding of the creation of the consumer society, and secondly to develop new methods using literature as a historical source: On the one hand, the Swedish fiction emerging during this time and pious literature, on the other.
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| 3. |
- Almgren, Matilda, et al.
(author)
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Fatigue after heart transplantation - a possible barrier to self-efficacy
- 2021
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In: Scandinavian Journal of Caring Sciences. - : Wiley. - 0283-9318 .- 1471-6712. ; 35:4, s. 1301-1308
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Journal article (peer-reviewed)abstract
- Rationale Recovery after heart transplantation is challenging and many heart recipients struggle with various transplant-related symptoms, side-effects of immunosuppressive medications and mental challenges. Fatigue has been reported to be one of the most common and distressing symptoms after heart transplantation and might therefore constitute a barrier to self-efficacy, which acts as a moderator of self-management. Aim To explore the prevalence of fatigue and its relationship to self-efficacy among heart recipients 1-5 years after transplantation. Research method An explorative cross-sectional design, including 79 heart recipients due for follow-up 1-5 years after transplantation. Three different self-assessment instruments were employed; The Multidimensional Fatigue Inventory-19, Self-efficacy for managing chronic disease 6-Item Scale and The Postoperative Recovery Profile. Ethical approval The study was approved by the Regional Ethics Board of Lund (Dnr. 2014/670-14/10) with supplementary approval from the Swedish Ethical Review Authority (Dnr. 2019-02769). Results The reported levels of fatigue for the whole group were moderate in all dimensions of the Multidimensional Fatigue Inventory-19, with highest ratings in the General Fatigue sub-scale. Those most fatigued were the groups younger than 50 years; pretransplant treatment with Mechanical Circulatory Support; not recovered or had not returned to work. Self-efficacy was associated with the sub-dimensions Mental Fatigue (rho = -0 center dot.649) and Reduced Motivation (rho = -0 center dot 617), which explained 40 center dot 1% of the variance when controlled for age and gender. Study limitations The small sample size constitutes a limitation. Conclusions The moderate levels of fatigue reported indicate that it is not a widespread problem. However, for those suffering from severe fatigue it is a troublesome symptom that affects the recovery process and their ability to return to work. Efforts should be made to identify those troubled by fatigue to enable sufficient self-management support.
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| 4. |
- Almgren, Matilda, et al.
(author)
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Self-efficacy, recovery and psychological wellbeing one to five years after heart transplantation: a Swedish cross-sectional study
- 2021
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In: European Journal of Cardiovascular Nursing. - : Oxford University Press (OUP). - 1474-5151 .- 1873-1953. ; 20:1
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Journal article (peer-reviewed)abstract
- Background Self-efficacy refers to a person ' s confidence in carrying out treatment-related activities and constitutes the foundation of self-management as well as long-term follow-up after heart transplantation. Exploring the heart recipients ' experiences by means of self-report instruments provides healthcare professionals with valuable information on how to supply self-management support after heart transplantation. Aims The aim was to explore self-efficacy in relation to the self-reported level of recovery and psychological wellbeing, among adult heart recipients, one to 5 years after transplantation. Methods This cross-sectional study includes 79 heart recipients, due for follow-up one to 5 years after transplantation. Three different self-assessment instruments were employed: the self-efficacy for managing chronic disease 6-item scale; the postoperative recovery profile; and the psychological general wellbeing instrument. Results The reported level of self-efficacy was high (median 8.3, maximum score 10). Significantly higher self-efficacy was seen among those who had returned to work (P = 0.003) and those without pre-transplant mechanical circulatory support (P = 0.033). In total, 65.5% (n = 52) reported being reasonably recovered, while 18.8% (n = 12) were not recovered. The median total psychological general wellbeing score was 108 (P-25 = 24,P-75 = 117), suggesting overall good psychological wellbeing in the whole group of heart recipients. Conclusion The heart transplant recipients in our study had an overall high level of self-efficacy. Low self-efficacy was found among those with a low self-reported level of recovery, pre-transplant treatment with mechanical circulatory support or who had not returned to work. This is important information for transplant professionals when helping heart recipients to balance their expectations about recovery.
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| 5. |
- Bagerius, Henric, 1974, et al.
(author)
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Methodological reflections on fiction in historical research : Skönlitteraturen i historievetenskapen – några metodologiska reflektioner
- 2013
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In: Historisk Tidskrift. - 0345-469X. ; 133:3, s. 384-410
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Journal article (peer-reviewed)abstract
- How can novels and short stories be used in historical research? There seems to be three different approaches to the relationship between fiction and society among Swedish historians today: Fiction as reflection of society, fiction as action that influences society and fiction as dialogue between text and society. The main advantage of using literary sources is that they can contribute to a deeper understanding of social phenomena. This is because novels and short stories are often biased, subjective and fictitious. Although the selection of appropriate novels and short stories for use in historical research raises questions of representativeness, similar methodological problems are part of all historical research. In general, it probably seems more proper to historians to choose realistic fiction that describes the contemporary society of the novelist, but this is not an absolute rule. Historians should not view the research methods employed to analyze fiction as particularly unique. Common historical approaches such as comparisons, argument analysis, discourse analysis of ideas, constructions and representations etc. can be applied to novels and short stories as well as to other types of written sources. In three readings of the same short story, 'Tvifvel' by Anne Charlotte Leffler, we provide three examples, based on different research interests, of how historians can analyze a fictional text. These examples also demonstrate different methodological approaches. One reading takes individual words and their meanings and connotations as a starting point. Another emphasizes dialogue in order to scrutinize the fictional characters' views and positions. A third reading focuses on key episodes in the story. As these readings show, fiction can be valuable in historical research by complicating, refining, and qualifying our understanding of the past.
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| 6. |
- Bagerius, Henric, 1974-, et al.
(author)
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Skönlitteraturen i historievetenskapen : några metodologiska reflektioner [Methodological reflections on fiction in historical research]
- 2013
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In: Historisk Tidskrift. - Stockholm : Svenska historiska föreningen. - 0345-469X .- 2002-4827. ; 133:3, s. 384-410
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Journal article (peer-reviewed)abstract
- How can novels and short stories be used in historical research? There seems to be three different approaches to the relationship between fiction and so- ciety among Swedish historians today: Fiction as reflection of society, fiction as action that influences society and fiction as dialogue between text and society. The main advantage of using literary sources is that they can contribute to a deeper understanding of social phenomena. This is because novels and short stories are often biased, subjective and fictitious. Although the selec- tion of appropriate novels and short stories for use in historical research raises questions of representativeness, similar methodological problems are part of all historical research. In general, it probably seems more proper to historians to choose realistic fiction that describes the contemporary society of the novelist, but this is not an absolute rule. Historians should not view the research methods employed to analyze fiction as particularly unique. Common historical approaches such as comparisons, argument analysis, discourse analysis of ideas, constructions and representations etc. can be ap- plied to novels and short stories as well as to other types of written sources. In three readings of the same short story, ‘Tvifvel’ by Anne Charlotte Lef- fler, we provide three examples, based on different research interests, of how historians can analyze a fictional text. These examples also demonstrate dif- ferent methodological approaches. One reading takes individual words and their meanings and connotations as a starting point. Another emphasizes dialogue in order to scrutinize the fictional characters’ views and positions. A third reading focuses on key episodes in the story. As these readings show, fiction can be valuable in historical research by complicating, refining, and qualifying our understanding of the past.
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| 7. |
- Bagerius, Henric, 1974, et al.
(author)
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Skönlitteraturen i historievetenskapen – några metodologiska reflektioner
- 2013
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In: Historisk Tidskrift. - 0345-469X. ; 133:3:3
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Journal article (peer-reviewed)abstract
- How can novels and short stories be used in historical research? There seems to be three different approaches to the relationship between fiction and so- ciety among Swedish historians today: Fiction as reflection of society, fiction as action that influences society and fiction as dialogue between text and society. The main advantage of using literary sources is that they can contribute to a deeper understanding of social phenomena. This is because novels and short stories are often biased, subjective and fictitious. Although the selec- tion of appropriate novels and short stories for use in historical research raises questions of representativeness, similar methodological problems are part of all historical research. In general, it probably seems more proper to historians to choose realistic fiction that describes the contemporary society of the novelist, but this is not an absolute rule. Historians should not view the research methods employed to analyze fiction as particularly unique. Common historical approaches such as comparisons, argument analysis, discourse analysis of ideas, constructions and representations etc. can be ap- plied to novels and short stories as well as to other types of written sources. In three readings of the same short story, ‘Tvifvel’ by Anne Charlotte Lef- fler, we provide three examples, based on different research interests, of how historians can analyze a fictional text. These examples also demonstrate dif- ferent methodological approaches. One reading takes individual words and their meanings and connotations as a starting point. Another emphasizes dialogue in order to scrutinize the fictional characters’ views and positions. A third reading focuses on key episodes in the story. As these readings show, fiction can be valuable in historical research by complicating, refining, and qualifying our understanding of the past.
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| 8. |
- Bagerius, Henric, 1974, et al.
(author)
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Vad vill vi med historielärarutbildningen?
- 2022
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In: Historisk tidskrift. - 0345-469X. ; 142:4
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Journal article (other academic/artistic)abstract
- En central del av verksamheten vid nästan alla institutioner som bedriver undervisning och forskning i historia är att utbilda historielärare. Historiker av facket diskuterar emellertid sällan frågor om lärarutbildningens innehåll och uppläggning, utöver de som knyter an till specifika historievetenskapliga sakområden. Vad behöver framtida historielärare kunna, och hur skiljer det sig eventuellt från vad framtida historiker bör kunna? Hur förhåller sig ämnesstudier till ämnesdidaktik och utbildningsvetenskap? Svaren på den typen av frågor har stor betydelse inte bara för lärarutbildningen utan för universitetsämnet historia och dess utövare i stort. Hur ska vi som historiker förhålla oss till det? Som en utgångspunkt för en sådan diskussion har en grupp historiker verksamma inom lärarutbildningen vid Göteborgs och Örebro universitet genomfört en inventering av historiedidaktiken i ämneslärarutbildningen vid tio av totalt sjutton svenska lärosäten där sådan utbildning med inriktning mot historia inom gymnasieskolan bedrivs idag. Med hjälp av publikt tillgänglig information och en enkät via epost till de ansvariga för utbildningarna har gruppen kartlagt historiedidaktiska kursmål och kurslitteratur, examensarbetenas inriktning och vem som undervisar i historiedidaktik. Medan det finns vissa gemensamma drag i hur målen för utbildningarna formuleras, visar genomgången på betydande variationer mellan lärosätena avseende kurslitteratur, examensarbeten och bemanning. Mot den bakgrunden diskuteras i denna idé- och debattartikel vad likheter och skillnader kan bero på samt om, och i så fall hur, det är ett problem att historielärarutbildningarna är så olika.
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| 9. |
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| 10. |
- Biru, Mulatu, et al.
(author)
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Caregiver-reported antiretroviral therapy non-adherence during the first week and after a month of treatment initiation among children diagnosed with HIV in Ethiopia
- 2017
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In: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV. - : Informa UK Limited. - 0954-0121. ; 29:4, s. 436-440
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Journal article (peer-reviewed)abstract
- To achieve optimal virologic suppression for children undergoing antiretroviral therapy (ART), adherence must be excellent. This is defined as taking more than 95% of their prescribed doses. To our knowledge, no study in Ethiopia has evaluated the level of treatment adherence at the beginning of the child's treatment. Our aim was therefore to evaluate caregiver-reported ART non-adherence among children and any predictors for this during the early course of treatment. We conducted a prospective cohort study of 306 children with HIV in eight health facilities in Ethiopia who were registered at ART clinics between 20 December 2014 and 20 April 2015. The adherence rate reported by caregivers during the first week and after a month of treatment initiation was 92.8% and 93.8%, respectively. Our findings highlight important predictors of non-adherence. Children whose caregivers were not undergoing HIV treatment and care themselves were less likely to be non-adherent during the first week of treatment (aOR = 0.17, 95% CI: 0.04, 0.71) and the children whose caregivers did not use a medication reminder after one month of treatment initiation (aOR = 5.21, 95% CI: 2.23, 12.16) were more likely to miss the prescribed dose. Moreover, after one month of the treatment initiation, those receiving protease inhibitor (LPV/r) or ABC-based treatment regimens were more likely to be non-adherent (aOR = 12.32, 95% CI: 3.25, 46.67). To promote treatment adherence during ART initiation in children, particular emphasis needs to be placed on a baseline treatment regimen and ways to issue reminders about the child's medication to both the health care system and caregivers. Further, large scale studies using a combination of adherence measuring methods upon treatment initiation are needed to better define the magnitude and predictors of ART non-adherence in resource-limited settings.
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