↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Lyytikäinen L. P) ;lar1:(su)"

Search: WFRF:(Lyytikäinen L. P) > Stockholm University

Result 1-3 of 3

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Ligthart, S., et al. (author) Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders 2018 In: American Journal of Human Genetics. - : Elsevier BV. - 0002-9297 .- 1537-6605. ; 103:5, s. 691-706 Journal article (peer-reviewed)
2.	Davies, G., et al. (author) Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function 2018 In: Nature Communications. - : Nature Publishing Group. - 2041-1723. ; 9:1 Journal article (peer-reviewed)abstract General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total N = 300,486; age 16-102) and find 148 genome-wide significant independent loci (P < 5 × 10-8) associated with general cognitive function. Within the novel genetic loci are variants associated with neurodegenerative and neurodevelopmental disorders, physical and psychiatric illnesses, and brain structure. Gene-based analyses find 709 genes associated with general cognitive function. Expression levels across the cortex are associated with general cognitive function. Using polygenic scores, up to 4.3% of variance in general cognitive function is predicted in independent samples. We detect significant genetic overlap between general cognitive function, reaction time, and many health variables including eyesight, hypertension, and longevity. In conclusion we identify novel genetic loci and pathways contributing to the heritability of general cognitive function.
3.	Evangelou, Evangelos, et al. (author) Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. 2018 In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 50:10, s. 1412-1425 Journal article (peer-reviewed)abstract High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-3 of 3

Refine your search

Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Schmidt, H. (2); Ford, I. (2); Li, S. (1); Liu, Y. (1); Wu, Y. (1); Yu, J. (1); show more...; Li, X. (1); Liu, T. (1); Willemsen, G (1); Davies, G (1); Kaprio, J (1); Peters, A (1); Vuoksimaa, E (1); Palviainen, T (1); Heinrich, J. (1); Huang, T. (1); Mahajan, A. (1); Wang, Y. (1); Zhu, G. (1); Sinisalo, J. (1); Gyllensten, Ulf B. (1); Melle, I (1); Djurovic, S (1); Larsson, Anders (1); Schnabel, R. (1); Luan, J. (1); Zhang, W. (1); Huang, J. (1); Abdollahi, M (1); Khaw, Kay-Tee (1); Balkau, B. (1); Langenberg, C. (1); Wareham, N. J. (1); Abbasi, A. (1); Karlsson, Magnus (1); Taylor, A. M. (1); Tanaka, T. (1); Amin, N (1); Yang, J. (1); Mueller, C. (1); Vandenput, Liesbeth, ... (1); Lorentzon, Mattias, ... (1); Scholz, M. (1); Nethander, Maria, 19 ... (1); Fischer, K. (1); Salomaa, Veikko (1); Jula, Antti (1); Perola, Markus (1); Corvin, A (1); Rujescu, D (1); show less...

University: Stockholm University (3)Undo refine; Karolinska Institutet (3); Uppsala University (2); Lund University (2); University of Gothenburg (1); Umeå University (1); show more...; Jönköping University (1); show less...

Language: English (3)

Research subject (UKÄ/SCB): Natural sciences (3); Medical and Health Sciences (3); Social Sciences (1)

Year: 2018 (3)

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view